Liquid–liquid phase separation in hepatocellular carcinoma
Frontiers in Cell and Developmental BiologyLiquid-liquid phase separation (LLPS) drives the formation of membraneless intracellular compartments within both cytoplasm and nucleus. These compartments can form distinct physicochemical environments, and in particular display different concentrations
Jianguo Xu +5 more
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Liquid-liquid phase separation drives skin barrier formation [PDF]
Science, 2020 Phase separation can be skin deep The skin's barrier arises from proliferative cells that generate a perpetual upward flux of terminally differentiating epidermal cells. Cells nearing the body surface suddenly lose their organelles, becoming dead cellular ghosts called squames.
Felipe Garcia Quiroz +6 more
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cAMP Buffering via Liquid–Liquid Phase Separation [PDF]
Function, 2021 Manuela Zaccolo
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Liquid–Liquid Phase Separation in Crowded Environments [PDF]
International Journal of Molecular Sciences, 2020 Biomolecular condensates play a key role in organizing cellular fluids such as the cytoplasm and nucleoplasm. Most of these non-membranous organelles show liquid-like properties both in cells and when studied in vitro through liquid–liquid phase separation (LLPS) of purified proteins.
Alain A. M. André, Evan Spruijt
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Modeling Elastically Mediated Liquid-Liquid Phase Separation [PDF]
Physical Review Letters, 2020 We propose a continuum theory of the liquid-liquid phase separation in an elastic network where phase-separated microscopic droplets rich in one fluid component can form as an interplay of fluids mixing, droplet nucleation, network deformation, thermodynamic fluctuation, \emph{etc}.
Xuefeng Wei +3 more
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Phase-separation phenomena in solutions of poly(2,6-dimethyl-1,4-phenylene oxide). I. Thermodynamic parameters of solutions in toluene [PDF]
, 1977 New experimental data have been collected on thermodynamic properties of solutions of poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) in toluene. The Flory-Huggins interaction parameters g have been determined from light scattering measurements.
Koenhen, D.M., Smolders, C.A.
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Liquid–liquid phase separation in autophagy
Journal of Cell Biology, 2020 Liquid–liquid phase separation (LLPS) compartmentalizes and concentrates biomacromolecules into distinct condensates. Liquid-like condensates can transition into gel and solid states, which are essential for fulfilling their different functions. LLPS plays important roles in multiple steps of autophagy, mediating the assembly of autophagosome formation
Nobuo N. Noda, Zheng Wang, Hong Zhang
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Phase separation in polymer solutions. I. Liquid-liquid phase separation of PPO poly (2, 6-dimethyl 1, 4-phenylene oxide) in binary mixtures with toluene and ternary mixtures with toluene and ethyl alcohol [PDF]
, 1972 In the system poly(2, 6-dimethy1-1, 4-phenylene oxide) (PPO)-toluene three phase separation lines can be detected: the melting point curve, the cloud point curve, and the spinodial.
Emmerik, P.T. van, Smolders, C.A.
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Liquid–liquid phase separation in artificial cells [PDF]
Interface Focus, 2018 Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of intracellular compartmentalization. Because the mechanisms driving phase separations are grounded in physical interactions, they can be recreated within less complex systems consisting of only a few simple components, to serve as artificial microcompartments.
Charles D. Crowe, Christine D. Keating
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Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]
, 2009 © 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey +112 more
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