Results 21 to 30 of about 6,019,478 (263)

Three Liquid-Liquid Phase Separation-Related Genes Associated with Prognosis in Glioma [PDF]

open access: yesPharmacogenomics and Personalized Medicine
Ling Lv,1 Xin Zhang,1 Yajun Liu,1 Xutong Zhu,2 Ruihan Pan,1 Lifa Huang1 1Department of Neurosurgery, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, People’s ...
Lv L   +5 more
doaj   +1 more source

An Overview of Liquid-Liquid Phase Separation and Its Mechanisms in Sepsis [PDF]

open access: yesJournal of Inflammation Research
Meiling Cao,1,* Xinyi Zhang,2,* Xiaohan Wang,2,* Danyang Zhao,2 Mingyue Shi,2 Jiahui Zou,2 Lei Li,3 Hongkun Jiang2 1Department of Neonatology, The First Hospital of China Medical University, Shenyang, Liaoning, 110001, People’s Republic of ...
Cao M   +7 more
doaj   +1 more source

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]

open access: yes, 2007
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core   +6 more sources

Liquid - liquid flows in microchannels [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Dore, V   +3 more
core   +6 more sources

Liquid–liquid phase separation in autophagy

open access: yesJournal of Cell Biology, 2020
Liquid–liquid phase separation (LLPS) compartmentalizes and concentrates biomacromolecules into distinct condensates. Liquid-like condensates can transition into gel and solid states, which are essential for fulfilling their different functions. LLPS plays important roles in multiple steps of autophagy, mediating the assembly of autophagosome formation
Nobuo N. Noda, Zheng Wang, Hong Zhang
openaire   +2 more sources

Liquid–liquid phase separation within fibrillar networks

open access: yesNature Communications, 2023
Complex fibrillar networks mediate liquid–liquid phase separation of biomolecular condensates within the cell. Mechanical interactions between these condensates and the surrounding networks are increasingly implicated in the physiology of the condensates
Jason X. Liu   +5 more
doaj   +1 more source

When liquid-liquid phase separation meets viral infections

open access: yesFrontiers in Immunology, 2022
Eukaryotic cells have both membranous and membraneless organelles. While the formation mechanism of membranous organelles is well understood, the formation mechanism of membraneless organelles remains unknown.
Wenqiang Wei   +10 more
doaj   +1 more source

Does Liquid-Liquid Phase Separation Drive Peptide Folding? [PDF]

open access: yes, 2020
Proline-arginine (PR) dipeptide repeats have been shown to undergo liquid-liquid phase separation and are an example of a growing number of intrinsically disordered proteins that can assemble into membraneless organelles.
Meredith R., Flanagan   +2 more
core   +1 more source

Liquid–liquid phase separation in artificial cells [PDF]

open access: yesInterface Focus, 2018
Abstract Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of intracellular compartmentalization. Because the mechanisms driving phase separations are grounded in physical interactions, they can be recreated within less complex systems consisting of only a few simple components, to serve as artificial ...
Charles D. Crowe, Christine D. Keating
openaire   +2 more sources

Targeting viral liquid–liquid phase separation [PDF]

open access: yesNature Reviews Microbiology, 2021
Two recent studies provide evidence that liquid–liquid phase separation during viral replication is a target for antiviral therapy.
openaire   +2 more sources

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