Results 31 to 40 of about 923,622 (282)
Cells, 2022 Membrane-enclosed organelle compartmentalization is not the only way by which cell processes are spatially organized. Phase separation is emerging as a new driver in the organization of membrane-less compartments and biological processes.
Klizia Maccaroni +3 more
doaj +1 more source
Crystal templating through liquid–liquid phase separation [PDF]
Chemical Communications, 2015 Fluff-like crystal growth of water in 1,2-dichloroethylene.
Mosses, Joanna +4 more
openaire +4 more sources
Kinase regulation by liquid–liquid phase separation
Trends in Cell Biology, 2023 Liquid-liquid phase separation (LLPS) is emerging as a mechanism of spatiotemporal regulation that could answer long-standing questions about how order is achieved in biochemical signaling. In this review we discuss how LLPS orchestrates kinase signaling, either by creating condensate structures that are sensed by kinases or by direct LLPS of kinases ...
Tania P. López-Palacios +1 more
openaire +2 more sources
Microfluidic characterization of macromolecular liquid-liquid phase separation [PDF]
Lab on a Chip, 2020 AbstractLiquid-liquid phase separation plays important roles in the compartmentalization of cells. Developing an understanding of how phase separation is encoded in biomacromolecules requires quantitative mapping of their phase behavior. Given that such experiments require large quantities of the biomolecule of interest, these efforts have been lagging
Anne Bremer +2 more
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Computation of liquid-liquid equilibria and phase stabilities: implications for RH-dependent gas/particle partitioning of organic-inorganic aerosols [PDF]
, 2010 Semivolatile organic and inorganic aerosol species partition between the gas and aerosol particle phases to maintain thermodynamic equilibrium. Liquid-liquid phase separation into an organic-rich and an aqueous electrolyte phase can occur in the aerosol ...
Marcolli, C. +3 more
core +3 more sources
Phase separation processes in polymer solutions in relation to membrane formation [PDF]
, 1996 This review covers new experimental and theoretical physical research related to the formation of polymeric membranes by phase separation of a polymer solution, and to the morphology of these membranes.
Berg, J.W.A. van den +3 more
core +2 more sources
Does Liquid-Liquid Phase Separation Drive Peptide Folding? [PDF]
Chemical Science, 2020 Proline-arginine (PR) dipeptide repeats have been shown to undergo liquid-liquid phase separation and are an example of a growing number of intrinsically disordered proteins that can assemble into membraneless organelles. These structures have been posited as a nucleation site for pathogenic protein aggregation.
Dean N. Edun +2 more
openaire +3 more sources
Comprehensive Regulation of Liquid–Liquid Phase Separation of Polypeptides
Molecules, 2023 The elucidation of the molecular driving forces responsible for Liquid–liquid Phase Separation (LLPS) of proteins and nucleic acids within living cells is crucial for understanding its biological functions and its role in related diseases. In the present
Yanwei Wang +3 more
doaj +1 more source
Modeling the gas-particle partitioning of secondary organic aerosol: the importance of liquid-liquid phase separation [PDF]
, 2012 The partitioning of semivolatile organic compounds between the gas phase and aerosol particles is an important source of secondary organic aerosol (SOA).
Seinfeld, J. H., Zuend, A.
core +3 more sources
Liquid–liquid phase separation in human health and diseases
Signal Transduction and Targeted Therapy, 2021 Emerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless organelles in eukaryotic cells (also known as biomolecular condensates or droplets).
Bin Wang +6 more
doaj +1 more source