Results 31 to 40 of about 333,263 (243)
CTP-controlled liquid–liquid phase separation of ParB
Journal of Molecular Biology, 2022 The ParABS system is supposed to be responsible for plasmid partitioning and chromosome segregation in bacteria. ParABS ensures a high degree of fidelity in inheritance by dividing the genetic material equally between daughter cells during cell division.
Babl, L. +5 more
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Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization
Frontiers in Chemistry, 2022 Biomineralization is a typical interdisciplinary subject attracting biologists, chemists, and geologists to figure out its potential mechanism. A mounting number of studies have revealed that the classical nucleation theory is not suitable for all ...
Da Qin, Zhen He, Peng Li, Shutian Zhang
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Effects of molecular weight and temperature on liquid–liquid phase separation in particles containing organic species and inorganic salts [PDF]
Atmospheric Chemistry and Physics, 2015 Atmospheric particles containing organic species and inorganic salts may undergo liquid–liquid phase separation when the relative humidity varies between high and low values.
Y. You, A. K. Bertram
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A Short Peptide Synthon for Liquid-Liquid Phase Separation
Nature Chemistry, 2020 Liquid-liquid phase separation of disordered proteins has emerged as a ubiquitous route to membraneless compartments in living cells, and similar coacervates may have played a role when the first cells formed. However, existing coacervates are typically made of multiple macromolecular components, and designing short peptide analogues capable of self ...
Manzar Abbas +4 more
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The effect of polymer length in liquid-liquid phase separation
Cell Reports Physical Science, 2023 Understanding the thermodynamics that drive liquid-liquid phase separation (LLPS) is quite important given the number of diverse biomolecular systems undergoing this phenomenon. Many studies have focused on condensates of long polymers, but very few systems of short-polymer condensates have been observed and studied.
Gilberto Valdes-Garcia +5 more
openaire +2 more sources
PLoS ONE, 2020 Some monoclonal antibodies undergo liquid-liquid phase separation owing to self-attractive associations involving electrostatic and other soft interactions, thereby rendering monoclonal antibodies unsuitable as therapeutics.
Tatsuji Matsuoka +3 more
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Liquid–Liquid Phase Separation and Protective Protein Aggregates in Bacteria
Molecules, 2023 Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles (MLOs) contribute to the spatiotemporal organization of various physiological processes in the cell.
Dorota Kuczyńska-Wiśnik +2 more
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Liquid-liquid crystalline phase separation of evolving amyloid fibrils
Physical Review Research, 2023 We study the conditions necessary for the onset of liquid-liquid crystalline phase separation (LLCPS) in a system of dynamically evolving amyloid fibrils whose kinetics is controlled by nucleation, growth and fragmentation.
Paride Azzari, Raffaele Mezzenga
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
LEF1 enhances β-catenin transactivation through IDR-dependent liquid–liquid phase separation
Life Science Alliance, 2023 This research elucidates the correlation between liquid–liquid phase separation (LLPS) of LEF1 with β-catenin and their transcriptional activation function, offering a novel therapeutic approach for the treatment of colorectal cancer through LLPS.
Bing Zhao +17 more
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