Results 41 to 50 of about 189,052 (363)

Cost-effectiveness analysis of capecitabine maintenance therapy plus best supportive care vs. best supportive care alone as first-line treatment of newly diagnosed metastatic nasopharyngeal carcinoma

Frontiers in Public Health, 2023
ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han, Xiaomeng Lan, Kun Tian, Xi Shen, Jinlan He, Nianyong Chen   +5 more
doaj   +1 more source

Advances in liquid biopsy in neuroblastoma

Fundamental Research, 2022
Even with intensive treatment of high-risk neuroblastoma (NB) patients, half of high-risk NB patients still relapse. New therapies targeting the biological characteristics of NB have important clinical value for the personalized treatment of NB. However, the current biological markers for NB are mainly analyzed by tissue biopsy.
Zhenjian Zhuo, Lei Lin, Lei Miao, Meng Li, Jing He   +4 more
openaire   +3 more sources

Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy

Breast Cancer Research, 2019
Background Breast cancer patients under neoadjuvant chemotherapy includes a heterogeneous group of patients who eventually develop distal disease, not detectable by current methods.
Alba Rodríguez-Martínez, Diego de Miguel-Pérez, Francisco Gabriel Ortega, José Luis García-Puche, Inmaculada Robles-Fernández, José Exposito, Jordi Martorell-Marugan, Pedro Carmona-Sáez, María del Carmen Garrido-Navas, Christian Rolfo, Hugh Ilyine, José Antonio Lorente, Marta Legueren, María José Serrano   +13 more
doaj   +1 more source

Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study. [PDF]

, 2016
BackgroundThis article describes a pilot study evaluating a novel liquid biopsy system for non-small cell lung cancer (NSCLC) patients. The electric field-induced release and measurement (EFIRM) method utilizes an electrochemical biosensor for detecting ...
Akin, David, Dong, Gaochao, Dong, Jingsi, Feng, Ziding, Li, Canjun, Li, Yin, Liang, Hao, Pu, Dan, Qiao, Youlin, Qin, Changlong, Qiu, Xiaoming, Sun, Tong, Tang, Xiaojun, Wan, Huajing, Wang, Xi, Wei, Fang, Wong, David TW, Xu, Lin, Yan, QingXiang, Zhang, Wenbiao, Zhen, Yan, Zhou, Qinghua, Zhu, Daxing   +22 more
core   +1 more source

The liquid biopsy in lung cancer [PDF]

Genes & Cancer, 2017
The incidence of lung cancer has significantly increased over the last century, largely due to smoking, and remains the most common cause of cancer deaths worldwide. This is often due to lung cancer first presenting at late stages and a lack of curative therapeutic options at these later stages.
Guillermo A. Herrera, Jungmi W. Yun, Rodney E. Shackelford, Youmna E. Moufarrej, Anvesh R. Kompelli, Junaid Ansari, Jonathan Steven Alexander   +6 more
openaire   +3 more sources

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation

Journal for ImmunoTherapy of Cancer, 2022
Cancer-related deaths are mainly caused by metastatic spread of tumor cells from the primary lesion to distant sites via the blood circulation.
Klaus Pantel, Catherine Alix-Panabières
doaj   +1 more source

Metabolomic Characterization of Human Model of Liver Rejection Identifies Aberrancies Linked to Cyclooxygenase (COX) and Nitric Oxide Synthase (NOS) [PDF]

, 2019
BACKGROUND Acute liver rejection (ALR), a significant complication of liver transplantation, burdens patients, healthcare payers, and the healthcare providers due to an increase in morbidity, cost, and resources.
Bettcher, Lisa, Ceballos, Brian, Ekser, Burcin, Ellensberg, Matthew, Elliott, Campbell M., Kubal, Chandrashekhar A., Maluccio, Mary A., Mangus, Richard S., Pepin, Robert, Raftery, Daniel, Saxena, Romil, Skill, Nicholas J.   +11 more
core   +1 more source

Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer [PDF]

, 2020
Background: Prostate cancer exhibits severe clinical heterogeneity and there is a critical need for clinically implementable tools able to precisely and noninvasively identify patients that can either be safely removed from treatment pathways or those ...
Bapat, Bharati, Brewer, Daniel, Clark, Jeremy, Connell, Shea P, Cooper, Colin, Hurst, Rachel, Mills, Robert, O'Reilly, Eve, Perry, Antoinette, Tuzova, Alexandra, Webb, Martyn, Zhao, Fang   +11 more
core   +1 more source

Tyrosine Kinase Inhibitors Could Be Effective Against Non-small Cell Lung Cancer Brain Metastases Harboring Uncommon EGFR Mutations

Frontiers in Oncology, 2020
Background: The significance of uncommon epidermal growth factor receptor (EGFR) mutations in patients with non-small cell lung cancer (NSCLC) and brain metastasis (BM) remains unclear.
Chunhua Ma, Juncheng Zhang, Juncheng Zhang, Dongjiang Tang, Dongjiang Tang, Xin Ye, Xin Ye, Jing Li, Ning Mu, Zhi Li, Renzhong Liu, Liang Xiang, Liang Xiang, Chuoji Huang, Chuoji Huang, Rong Jiang   +15 more
doaj   +1 more source

Liquid Biopsy in Oral Cancer [PDF]

International Journal of Molecular Sciences, 2018
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a complex process, in which heterogeneity plays an important role in the development and progression of the disease. This review provides an overview of the current biological and clinical significance of circulating tumour cells (CTCs), circulating tumour DNA (ctDNA),
Óscar Rapado-González, María Mercedes Suárez-Cunqueiro, María Mercedes Suárez-Cunqueiro, Rafael López-López, Laura Muinelo-Romay, Jose-Luis Lopez-Cedrun, Fatima Lousada-Fernandez   +6 more
openaire   +3 more sources