Results 31 to 40 of about 3,770 (149)

Pharmacological characterization of liquiritigenin, a chiral flavonoid in licorice

Research in Pharmaceutical Sciences, 2016
Liquiritigenin is a chiral flavonoid present in plant based food, nutraceuticals, and traditional medicines. It is also an important ingredient present in licorice.
Samaa Alrushaid, Neal M Davies, Stephanie E Martinez, Casey L Sayre   +3 more
doaj   +1 more source

Investigation on the simultaneous inhibition of advanced glycation end products, 4-methylimidazole and hydroxymethylfurfural in thermal reaction meat flavorings by liquiritigenin, liquiritin and glycyrrhizic acid and possible pathways

, 2023
The inhibitory effects of liquiritigenin, liquiritin and glycyrrhizic acid against the hazards during the preparation of thermal reaction beef flavoring were investigated using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
Zhiyong He, Peng Deng, Chen, Qiuming, ÖZ, Emel, He, Zhiyong, Wang, Qifan, Jie Chen, Zeng, Maomao, Qifan Wang, Fatih Oz, Chang, Haolong, Chen, Jie, Zhaojun Wang, Emel Oz, ÖZ, Fatih, Wang, Zhaojun, Fang Qin, Qin, Fang, Qiuming Chen, Maomao Zeng, Haolong Chang, Deng, Peng   +21 more
core   +1 more source

Liquiritigenin reduces blood glucose level and bone adverse effects in hyperglycemic adult zebrafish [PDF]

, 2019
Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia that induces other pathologies including diabetic retinopathy and bone disease.
Luzi L., Terruzzi I., Mariotti M., Carnovali M., Banfi G.   +4 more
core   +2 more sources

Stereospecific pharmacokinetic characterization of liquiritigenin in the rat

Research in Pharmaceutical Sciences, 2017
Liquiritigenin is a chiral flavonoid present in licorice and other medicinal plants. The nature of its biological fate with respect to the individual enantiomers has not been examined.
Samaa Alrushaid, Neal M Davies, Stephanie E Martinez, Casey L Sayre   +3 more
doaj   +1 more source

Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5HT3A receptors due to the action of flavonoids

Frontiers in Pharmacology, 2015
The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of gastrointestinal motility disorders, cachexia and nausea.
Robin eHerbrechter, Paul M Ziemba, Katrin M Hoffmann, Hanns eHatt, Markus eWerner, Guenter eGisselmann   +5 more
doaj   +1 more source

Combined computational approaches for developing new anti-Alzheimer drug candidates: 3D-QSAR, molecular docking and molecular dynamics studies of liquiritigenin derivatives

Heliyon, 2022
Butyrylcholinesterase is an acetylcholine-degrading enzyme involved in the memorization process, which is becoming an interesting target for the symptomatic treatment of Alzheimer's disease.
Hassan Nour, Ossama Daoui, Oussama Abchir, Souad ElKhattabi, Salah Belaidi, Samir Chtita   +5 more
doaj   +1 more source

C5-Hydroxylation of liquiritigenin is catalyzed selectively by CYP1A2

, 2011
C5-Hydroxylation of liquiritigenin is catalyzed selectively by CYP1A21. Liquiritigenin (7,4'-dihydroxyflavone), the primary active component of a traditional Chinese medicine Glycyrrhizae radix, has a wide range of pharmacological activities.
Tu, Cai-Xia, Hu, Ying, Wang, Ao-Xue, Liu, Hui-Xin, Hui-XinLiu, Liu, Yong, Qi, Xiao-Yi, Yang, Ling   +7 more
core   +1 more source

Production of Sinorhizobium meliloti nod Gene Activator and Repressor Flavonoids from Medicago sativa Roots

Molecular Plant-Microbe Interactions, 1998
During symbiosis between leguminous plants and rhizobia, flavonoids exuded by the plants act as chemoattractants and nodulation (nod) gene regulators in the other partner.
José Angelo Silveira Zuanazzi, Pierre Henri Clergeot, Jean-Charles Quirion, Henri-Philippe Husson, Adam Kondorosi, Pascal Ratet   +5 more
doaj   +1 more source

Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats

Molecules, 2015
Most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or unchanged forms. Metabolic and pharmacokinetic studies are therefore necessary to understand the pharmacological mechanisms of polyphenols. Jumihaidokuto (
Takashi Matsumoto, Yousuke Matsubara, Yasuharu Mizuhara, Kyoji Sekiguchi, Junichi Koseki, Kazuaki Tsuchiya, Hiroaki Nishimura, Junko Watanabe, Atsushi Kaneko, Kazuya Maemura, Tomohisa Hattori, Yoshio Kase   +11 more
doaj   +1 more source

Quantitative Analysis of Flavonoids in Glycyrrhiza uralensis Fisch by 1H-qNMR

Journal of Analytical Methods in Chemistry, 2021
Objective. To establish a method for simultaneous determination of liquiritin, liquiritigenin, and isoliquiritinin glycyrrhizin using hydrogen nuclear magnetic resonance quantitative technology (1H-qNMR). Methodology.
Ping Yu, Qian Li, Yanmei Feng, Yuying Chen, Sinan Ma, Xiaoqin Ding   +5 more
doaj   +1 more source