Results 11 to 20 of about 3,770 (149)

Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function

Molecules, 2022
Acute kidney injury (AKI) induced by cisplatin (CP), a first-line anticancer drug for chemotherapy, is common. To date, there is an urgent need to find effective treatments to reduce the nephrotoxicity caused by CP.
Meng Zhou, Yanpeng Dai, Yong Ma, Yi Yan, Min Hua, Qi Gao, Xue Geng, Qian Zhou   +7 more
doaj   +2 more sources

Prenylation of Flavanones by an Aromatic Prenyltransferase from Fusarium globosum [PDF]

Molecules
Prenylation increases the structural diversity and biological activity of flavonoids. In this study, an aromatic prenyltransferase, FgPT1, was identified from Fusarium globosum.
Dingtao Tang, Jiajie Quan, Zhengjiao Gao, Bingfeng He, Yu Hou, Peipei Fan, Meidong Pan, Jiali Yang   +7 more
doaj   +3 more sources

Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms. [PDF]

PLoS ONE, 2013
The increased cancer risk associated with hormone therapies has encouraged many women to seek non-hormonal alternatives including botanical supplements such as hops (Humulus lupulus) and licorice (Glycyrrhiza spec.) to manage menopausal symptoms ...
Atieh Hajirahimkhan, Charlotte Simmler, Yang Yuan, Jeffrey R Anderson, Shao-Nong Chen, Dejan Nikolić, Birgit M Dietz, Guido F Pauli, Richard B van Breemen, Judy L Bolton   +9 more
doaj   +9 more sources

Spectroscopic and Docking Studies on the Binding of Liquiritigenin with Hyaluronidase for Antiallergic Mechanism

Scientifica, 2016
The inhibitory effect of liquiritigenin on hyaluronidase and its binding mechanism were investigated systematically by UV-vis absorption, fluorescence, and molecular modeling approaches.
Hua-jin Zeng, Ran Yang, Jing You, Ling-bo Qu, Yan-jun Sun   +4 more
doaj   +2 more sources

Simultaneous Determination and Pharmacokinetic Characterization of Glycyrrhizin, Isoliquiritigenin, Liquiritigenin, and Liquiritin in Rat Plasma Following Oral Administration of Glycyrrhizae Radix Extract

Molecules, 2019
Glycyrrhizae Radix is widely used as herbal medicine and is effective against inflammation, various cancers, and digestive disorders. We aimed to develop a sensitive and simultaneous analytical method for detecting glycyrrhizin, isoliquiritigenin ...
You Jin Han, Bitna Kang, Eun-Ju Yang, Min-Koo Choi, Im-Sook Song   +4 more
doaj   +2 more sources

Liquiritigenin Inhibits Tumor Growth and Vascularization in a Mouse Model of Hela Cells

Molecules, 2012
Angiogenesis is one of the crucial steps in the transition of a tumor from a small, harmless cluster of mutated cells to a large, malignant growth, capable of spreading to other organs throughout the body.
Yuxin Liu, Sirou Xie, Yu Wang, Kang Luo, Yang Wang, Yunqing Cai   +5 more
doaj   +2 more sources

Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women’s breast tissue

Scientific Reports, 2023
Breast cancer risk continues to increase post menopause. Anti-estrogen therapies are available to prevent postmenopausal breast cancer in high-risk women. However, their adverse effects have reduced acceptability and overall success in cancer prevention.
Atieh Hajirahimkhan, Caitlin Howell, Elizabeth T. Bartom, Huali Dong, Daniel D. Lantvit, Xiaoling Xuei, Shao-Nong Chen, Guido F. Pauli, Judy L. Bolton, Susan E. Clare, Seema A. Khan, Birgit M. Dietz   +11 more
doaj   +2 more sources

Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis

Molecules, 2020
Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities.
Geum Seok Jeong, Myung-Gyun Kang, Joon Yeop Lee, Sang Ryong Lee, Daeui Park, MyoungLae Cho, Hoon Kim   +6 more
doaj   +2 more sources

Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways

Medicines, 2019
Background: Liquiritin (LQ) and its aglycone, liquiritigenin (LQG), are major flavonoids in licorice root (Glycyrrhiza spp.). Our preliminary screening identified LQ and LQG, which promote melanin synthesis in the melanoma cells.
Takuhiro Uto, Tomoe Ohta, Akihisa Yamashita, Shunsuke Fujii, Yukihiro Shoyama   +4 more
doaj   +2 more sources

Liquiritigenin-loaded poly (acrylic acid)-carboxymethyl cellulose hydrogels: formulation optimization, performance evaluation, and assessment of therapeutic efficacy for wound healing and sepsis caused by wound bacterial infection [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionBacterial wound infections that lead to sepsis pose a major clinical challenge. This study aims to develop and optimize a novel cross-linked poly(acrylic acid)/carboxymethylcellulose sodium (PAA/CMC-Na) hydrogel encapsulating liquiritigenin ...
Xiang Meng, Xiang Meng, Muzhou Xue, Zequn Zeng, Wenbin Pei, Bing Gong   +5 more
doaj   +2 more sources