Results 101 to 110 of about 8,390 (226)

The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study. [PDF]

, 2015
The establishment and maintenance of neuronal circuits depends on tight regulation of synaptic contacts. We hypothesized that CNTNAP2, a protein associated with autism, would play a key role in this process.
Gdalyahu, Amos, Geschwind, Daniel H, Golshani, Peyman, Lazaro, Maria, Penagarikano, Olga, Trachtenberg, Joshua T   +5 more
core   +2 more sources

Lis1 finds new digs on the desmosome [PDF]

Journal of Cell Biology, 2011
![Figure][1] The centrosomal protein Lis1 (green) localizes to the cortex of differentiated epithelial cells. A protein that stabilizes microtubules also helps maintain desmosomes, [Sumigray et al.][2] report.
openaire   +2 more sources

Linking secretion and cytoskeleton in immunity– a case for Arabidopsis TGNap1

BioEssays, Volume 46, Issue 11, November 2024.
Intracellular trafficking, particularly in defense, depends on F‐actin and microtubules (MTs). Cytoskeleton‐Organelle Bridging Proteins (COBPs) link vesicles to these structures, ensuring directional transport. While the specifics of this association are unclear, TGNap1 has been identified as a crucial MT‐binding COBP for defense trafficking ...
Deepak D. Bhandari, Federica Brandizzi
wiley   +1 more source

Supporting process reuse in PROMENADE [PDF]

, 2002
Process reuse (the ability to construct new processes by assembling already built ones) and process harvesting (the ability to build generic processes that may be further reused, from existing ones) are two crucial issues in process technology.
Franch Gutiérrez, Javier, Ribó Trujillo, Josep M.   +1 more
core   +1 more source

Comparative structural study on axonemal and cytoplasmic dyneins

Cytoskeleton, Volume 81, Issue 11, Page 681-690, November 2024.
Abstract Axonemal dyneins are the driving force of motile cilia, while cytoplasmic dyneins play an essential role in minus‐end oriented intracellular transport. Their molecular structure is indispensable for an understanding of the molecular mechanism of ciliary beating and cargo transport. After some initial structural analysis of cytoplasmic dyneins,
Noemi Zimmermann, Takashi Ishikawa
wiley   +1 more source

Antecedents and outcomes of consumer environmentally friendly attitudes and behaviour [PDF]

, 2010
With the intensification of problems relating to the environment, a growing number of consumers are becoming more ecologically conscious in their preferences and purchases of goods.
Aitken L., Bentler P.M., Byrne B.M., Constantinos N. Leonidou, Dunlap R.E., Eigner S., Ellen P.S., Festinger L., Flatters P., García-Rosell J.-C., Hair J.F., Hofstede G., Hofstede G., Jones A., Kim Y., Kline R.B., Leonidas C. Leonidou, Levin G., Light H., Mayer F.S., McCarty J., Melillo W., Newell S.J., Nigbur D., Nisbet E.K., Nunnally J.C., O'Neill J., Olga Kvasova, Olli E., Paim L., Paladino A., Pickett G.M., Porritt J., Schuhwerk M.E., Shabecoff P., Sinha J.B.P., Sohr S., Solomon M., Triandis H.C.   +38 more
core   +3 more sources

WONOEP appraisal: Genetic insights into early onset epilepsies

Epilepsia, Volume 65, Issue 11, Page 3138-3154, November 2024.
Abstract Early onset epilepsies occur in newborns and infants, and to date, genetic aberrations and variants have been identified in approximately one quarter of all patients. With technological sequencing advances and ongoing research, the genetic diagnostic yield for specific seizure disorders and epilepsies is expected to increase.
Anne Quatraccioni, Silvia Cases‐Cunillera, Ganna Balagura, Matthew Coleman, Laura Rossini, James D. Mills, Pablo M. Casillas‐Espinosa, Solomon L. Moshé, Raman Sankar, Stéphanie Baulac, Jeffrey L. Noebels, Stéphane Auvin, Terence J. O'Brien, David C. Henshall, Özlem Akman, Aristea S. Galanopoulou   +15 more
wiley   +1 more source

Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein

Cell Reports, 2015
Axonal transport is essential for neuronal function, and defects in transport are associated with multiple neurodegenerative diseases. Aberrant cyclin-dependent kinase 5 (CDK5) activity, driven by the stress-induced activator p25, also is observed in ...
Eva Klinman, Erika L.F. Holzbaur
doaj   +1 more source

Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes [PDF]

, 2019
Cytoplasmic dynein is a minus-end-directed microtubule-based motor that acts at diverse subcellular sites. During mitosis, dynein localizes simultaneously to the mitotic spindle, spindle poles, kinetochores and the cell cortex.
Cheeseman, Iain M, Monda, Julie Kathryn
core   +1 more source

Diagnostic work‐up in malformations of cortical development

Developmental Medicine &Child Neurology, Volume 66, Issue 8, Page 974-989, August 2024.
Malformations of cortical development (MCDs) represent a heterogeneous spectrum of disorders, characterized by abnormal development of the cerebral cortex. Many MCDs are of genetic origin, although acquired factors can lead to similar phenotypes. In this narrative review, we provide an overview of the diagnostic approach to MCD, illustrated with ...
Ellen Rijckmans, Katrien Stouffs, Anna C. Jansen   +2 more
wiley   +1 more source