Results 251 to 260 of about 26,671 (292)

Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research. [PDF]

J Virol
García-Rodríguez I, García-Dorival I, Alonso C, Cuesta-Geijo MÁ.   +3 more
europepmc   +1 more source

Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer. [PDF]

Signal Transduct Target Ther
Lim JH, Mun SJ, Kang HM, Yu WD, Oh SJ, Lee JY, Son YS, Lee S, Kim DS, Lee J, Kim SJ, Cho HS, Son MJ, Son MY, Jung CR.   +14 more
europepmc   +1 more source

Next-Generation Hydrogels for Biliary Organoid Engineering. [PDF]

Pharmaceuticals (Basel)
Marfoglia A, Sorrentino G.
europepmc   +1 more source

<i>DNASE1L3</i> Mediates Hepatocellular Carcinoma Tumor Growth and Organoid Models via the Wnt/<b>β</b>-Catenin Signaling Pathway. [PDF]

Oncol Res
Zhang S, Zhao Y, Geng L, Song F, Feng L, Jiang J, Cai Q, Fan F.   +7 more
europepmc   +1 more source

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Culture of Mouse Liver Ductal Organoids

2022
3D organoid culture has become a powerful tool and model for various human diseases, including liver diseases, such as non-alcoholic steatohepatitis (NASH). Hepatic organoids have significant advantages over traditional primary cell cultures. The hepatic progenitor cells can be induced to form hepatic organoids.
Junkai, Yan, Yunling, Tai, Huiping, Zhou
openaire   +2 more sources

Advances in liver organoids: model systems for liver disease

Archives of Pharmacal Research, 2022
Reliable in vitro models with human-derived cells that recapitulate in vivo-like physiologies are required for drug discovery and development to reduce the gap between the results of cell-based drug testing, animal testing, and human clinical trials. Liver organoid models have emerged as novel tools for hepatotoxicity evaluation, liver disease modeling,
Jaeseo Lee, Seon Ju Mun, Yongbo Shin, Seonbhin Lee, Myung Jin Son   +4 more
openaire   +2 more sources

Organoids for Liver Stage Malaria Research

Trends in Parasitology, 2020
Plasmodium parasites cause malaria and are maintained between Anopheles mosquitoes and mammalian hosts in a complex life cycle. Malaria parasites occupy tissue niches that can be difficult to access, and models to study them can be challenging to recapitulate experimentally, particularly for Plasmodium species that infect humans.
Ronan, Mellin, Justin A, Boddey
openaire   +2 more sources