Correction: Human liver organoids are susceptible to Plasmodium vivax infection. [PDF]
Nitaramorn N +5 more
europepmc +1 more source
Tissue engineering of vascularised human liver organoids: study of morphology phenotypic expression and metabolomics of transitional co-cultures of hepatic/endothelial progenitors [PDF]
Leonard J. Nelson +7 more
openalex +1 more source
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li +12 more
wiley +1 more source
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang +11 more
wiley +1 more source
Temporal proteomic profiling of iPSC-derived human liver organoids reveals optimal maturation for drug metabolism and toxicology. [PDF]
Yang S, Hao J, Ooka M, Xia M.
europepmc +1 more source
Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies [PDF]
Sandro Nuciforo +12 more
openalex +1 more source
Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen +11 more
wiley +1 more source
Protocol for generating liver organoids containing Kupffer cells using human iPSCs. [PDF]
Li Y, Nie Y, Taniguchi H.
europepmc +1 more source
Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids [PDF]
Bing Zhao +17 more
openalex +1 more source

