Results 31 to 40 of about 449,258 (311)

Effect of a reduction in glomerular filtration rate after nephrectomy on arterial stiffness and central hemodynamics: rationale and design of the EARNEST study [PDF]

, 2014
Background: There is strong evidence of an association between chronic kidney disease (CKD) and cardiovascular disease. To date, however, proof that a reduction in glomerular filtration rate (GFR) is a causative factor in cardiovascular disease is ...
Alam, Arena, Bahous, Benetos, Blacher, Blacher, Boudville, Briet, Charles J. Ferro, Charles R. Tomson, Chue, Chue, Daniel Zehnder, DeLoach, Doucende, Edwards, Eknoyan, Faul, Fehrman-Ekholm, Foley, Forbat, Frimodt-Moller, Garg, Go, Groenink, Grothues, Guerin, Hametner, Ian B. Wilkinson, Ibrahim, Jackson, John R. Cockcroft, Jonathan N. Townend, Kasiske, Krohn, Landray, Lang, Laurent, Laurie A. Tomlinson, Levey, Lewington, Luzardo, Maceira, Madero, Mafham, Mark, Martensson, Matsushita, Michels, Moody, Moody, Myerson, Nagueh, National Kidney Foundation, O'Brien, Patrick B. Mark, Richard P. Steeds, Rook, Rothwell, Savage, Schiffrin, Schiller, Segev, Tavakol, Townsend, Vickery, Wang, Wei, Weiss, Wiesmann, Wilkinson, William E. Moody, Yeon, Young   +73 more
core   +2 more sources

HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation

Signal Transduction and Targeted Therapy, 2021
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia.
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang, Jing Xu, Hong Yang, Yuanchang Hu, Jiannan Qiu, Liyong Pu, Jinhai Tang, Xuehao Wang   +10 more
doaj   +1 more source

Decision making around living and deceased donor kidney transplantation: a qualitative study exploring the importance of expected relationship changes [PDF]

, 2012
BACKGROUND: Limited data exist on the impact of living kidney donation on the donor-recipient relationship. Purpose of this study was to explore motivations to donate or accept a (living donor) kidney, whether expected relationship changes influence ...
Andrzej G Baranski, Anne M Stiggelbout, Ingrid B de Groot, Karen Schipper, null null, Paul J M van der Boog, Perla J Marang-van de Mheen, Sandra van Dijk   +7 more
core   +1 more source

Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing

Redox Biology, 2022
Single-cell RNA-sequencing (scRNA-seq) presents better insights into cell behavior in the context of a complex tumor microenvironment by profiling single-cell populations.
Xiaopei Hao, Zhiying Zheng, Hanyuan Liu, Yao Zhang, Junwei Kang, Xiangyi Kong, Dawei Rong, Guangshun Sun, Guoqiang Sun, Li Liu, Haibo Yu, Weiwei Tang, Xuehao Wang   +12 more
doaj   +1 more source

First two cases of living related liver transplantation with complicated anatomy of blood vessels in Beijing [PDF]

, 2004
Aim: Living related liver transplantation (LRLT) has been developed in response to the paediatric organ donor shortage. Though it has been succeeded in many centers worldwide, the safety of the donor is still a major concern, especially in donors with ...
Chen, CL, Fan, ST, Huang, YT, Lee, L, Wan, YL, Wu, WH, Yang, YM   +6 more
core   +1 more source

Defective efferocytosis by aged macrophages promotes STING signaling mediated inflammatory liver injury

Cell Death Discovery, 2023
Aged livers have shown aggravated liver ischemia and reperfusion (IR) injury. Timely efferocytosis of apoptotic cells is a key mechanism for avoiding excessive inflammation and tissue injury.
Haoran Hu, Xuyu Cheng, Fei Li, Zhu Guan, Jian Xu, Dongming Wu, Yiyun Gao, Xinyu Zhan, Ping Wang, Haoming Zhou, Zhuqing Rao, Feng Cheng   +11 more
doaj   +1 more source

Nogo-B is a key mediator of hepatic ischemia and reperfusion injury

Redox Biology, 2020
Nogo-B is an endoplasmic reticulum-residential protein with distinctive functions in different diseases. However, it remains unclear the role of Nogo-B in liver sterile inflammatory injury.
Jianhua Rao, Feng Cheng, Haoming Zhou, Wenjie Yang, Jiannan Qiu, Chao Yang, Xuehao Ni, Shikun Yang, Yongxiang Xia, Xiongxiong Pan, Feng Zhang, Ling Lu, Xuehao Wang   +12 more
doaj   +1 more source

Systems of donor transfer [PDF]

, 1993
The development of medical knowledge has resulted in a demand in society for donor organs, but the recruitment of donor organs for transplantation is difficult.
Akveld, J.E.M. (Hans), Charro, F.T. (Frank) de, Hessing, E. (Ellen)   +2 more
core   +1 more source

Patient-Benefactors Support New Kidney Transplant Center [PDF]

, 2017
December 14, 2017 was a landmark day at Jefferson: the ribbon cutting ceremony of the Nicoletti Kidney Transplant Center at Jefferson. This milestone venture – bringing together research, education and clinical care in one space – came to fruition thanks

core   +1 more source

A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury: a protocol of a randomised controlled trial [PDF]

, 2017
Background: Optimal treatment for established renal failure is living donor kidney transplantation. However this pathway exposes healthy individuals to significant reduction in nephron mass via major surgical procedure.
Aitken, Emma, Clancy, Marc, Ghita, Ryan, Mackinnon, Shona   +3 more
core   +1 more source