Results 121 to 130 of about 1,819 (163)

Protein quality control and antigen presentation in the development of hepatitis B-related hepatocellular carcinoma. [PDF]

Front Pharmacol
An L, Han Y, Sun X, Wang L, Guo L.
europepmc   +1 more source

Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice. [PDF]

J Neuroinflammation
Sironi F, Tortarolo M, Mazzucchi S, Camporeale L, Freschi M, Arcadipane E, De Giovanetti G, Kurosaki M, Terao M, Parlanti P, Podini P, Gentile F, Bonetto V, Cappello V, Riva N, Quattrini A, Bendotti C.   +16 more
europepmc   +1 more source

Out of the Cold: Does the Immunoproteasome Play a Role in Kidney Graft Function after Cold Storage? [PDF]

Kidney360
O'Connor PM.
europepmc   +1 more source

Defining the Molecular Intricacies of Human Papillomavirus-Associated Tonsillar Carcinoma. [PDF]

Cancer Control
Sethi S.
europepmc   +1 more source

Step-by-step: the CD8 T cell journey in leishmaniasis. [PDF]

mBio
Fowler EA, Novais FO.
europepmc   +1 more source

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LMP7 inhibits the activation of NLRP3 inflammasome through interaction with NLRP3

Biochemical and Biophysical Research Communications, 2020
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) by coding pattern recognition receptors (PRRs). As a well-known inflammasome, NLRP3 plays an essential role in helping the host immune response and driving antiviral processes.
Jing Jin, Wenbiao Wang, Aixin Li
exaly   +3 more sources

LMP7 polymorphism in Japanese patients with sarcoidosis and Behçet's disease

Human Immunology, 1996
To evaluate the influence of the MHC-linked LMP7 gene on disease susceptibility in HLA class I and class II-associated diseases, the distribution of LMP7 alleles was determined using the PCR-RFLP method in 69 Japanese patients with Behçet's disease, 65 patients with sarcoidosis, and 100 unrelated healthy controls.
M, Ishihara, S, Ohno, N, Mizuki, N, Yamagata, T, Ishida, T, Naruse, A, Ando, H, Inoko   +7 more
openaire   +2 more sources

No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM

Diabetes, 1997
Results from a recent study suggested that polymorphisms within the HLA class II genes LMP2 and LMP7 were associated with the susceptibility for developing IDDM, and that this association could not be explained by linkage disequilibrium to HLA-DR or -DQ genes.
D E, Undlien, H E, Akselsen, G, Joner, K, Dahl-Jørgensen, O, Søvik, K S, Rønningen, E, Thorsby   +6 more
openaire   +2 more sources

Divergent intron arrangement in theMB1/LMP7 proteasome gene pair

Immunogenetics, 1996
We sequenced the human MB1 gene from a cosmid clone mapping to chromosome 14q11.2-12. The gene spans about 6 kilobases and contains three exons and two introns. There was no evidence of an alternative leader exon, which is a characteristic of the major histocompatibility complex (MHC)-encoded LMP7 gene, the closest relative of MB1, with which it shares
S, Abdulla, S, Beck, M, Belich, A, Jackson, T, Nakamura, J, Trowsdale   +5 more
openaire   +2 more sources