Results 101 to 110 of about 2,385 (193)

Relationship between age and expression of genes coding β-catenin (CTNNB1) (A), CacyBP/SIP (B), galectin-3 (LGALS3) (C) and LMP7 (PSMB8) (D) in the men heart.

, 2020
Relationship between age and expression of genes coding β-catenin (CTNNB1) (A), CacyBP/SIP (B), galectin-3 (LGALS3) (C) and LMP7 (PSMB8) (D) in the men heart.
Irena Kasacka (8520003), Wojciech Łebkowski (8520015), Żaneta Piotrowska (8520006), Alicja Lewandowska (8520012), Michał Niezgoda (8520009)   +4 more
core   +1 more source

Innate immune responses against P. yoelii in LMP7-deficient mice.

, 2013
(A) Splenic CD11c+ dendritic cells obtained from WT (upper panels) and LMP7-deficient mice (lower panels) 5 days after infection were analyzed for their expression of activation markers.
Makoto Hirai (227542), Hiroko Okada (391891), Hajime Hisaeda (391893), Liping Tu (391888), Kazutomo Suzue (115420), Bin Chou (391887), Chikako Shimokawa (391892), Tomoyo Taniguchi (391890), Takashi Imai (24800), Kunisuke Himeno (391889), Xuefeng Duan (391886)   +10 more
core   +1 more source

Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice

, 2017
New treatment options and drug targets for colorectal carcinoma are a pressing medical need. Inflammation and pro-inflammatory cytokines produced by Th1 and Th17 cells like IL-6, TNF, IL-17 and IL-23 promote the development and growth of colorectal ...
Thomas Brunner, Julia Koerner, Gröttrup, Marcus, Brunner, Thomas, Körner, Julia, Marcus Groettrup   +5 more
core   +1 more source

Inhibition of Immunoproteasome Attenuates NLRP3 Inflammasome Response by Regulating E3 Ubiquitin Ligase TRIM31

Cells
Excessive secretion of pro-inflammatory cytokines leads to the disruption of intestinal barrier in inflammatory bowel disease (IBD). The inflammatory cytokine tumor necrosis factor alpha (TNFα) induces the assembly of the NLRP3 inflammasome, resulting in
Yubin Lee, Boran Yoon, Sumin Son, Eunbin Cho, Kyung Bo Kim, Eun Young Choi, Dong-Eun Kim   +6 more
doaj   +1 more source

EXPRESSION OF GENES ENCODING IMMUNOPROTEASOME SUBUNITS INDUCIBLE BY MACROPHAGES INFECTED WITH M. bovis BGC AND M. Tuberculosis H37RV

Туберкулез и болезни лёгких, 2014
To study the effect of M. bovis BCG vaccine strain and virulent laboratory M. tuberculosis H37Rv strain on the expression of macrophageinducible immunoproteasome subunits, a real-time reverse-transcription polymerase chain reaction technique using cDNA ...
S. N. Andreevskaya, T. G. Smirnova, A. V. Timofeev, E. E. Larionova, L. N. Chernousova   +4 more
doaj  

MRI-based machine learning reveals proteasome subunit PSMB8-mediated malignant glioma phenotypes through activating TGFBR1/2-SMAD2/3 axis

Molecular Biomedicine
Gliomas are the most prevalent and aggressive neoplasms of the central nervous system, representing a major challenge for effective treatment and patient prognosis.
Dongling Pei, Zeyu Ma, Yuning Qiu, Minkai Wang, Zilong Wang, Xianzhi Liu, Long Zhang, Zhenyu Zhang, Ran Li, Dongming Yan   +9 more
doaj   +1 more source

Evaluation of substituted psoralenes as inhibitors of the LMP7 subunit of immunoproteasome [PDF]

, 2016
Proteasom je multikatalitični kompleks, ki homeostazo celice vzdržuje preko odstranjevanja nepravilno zvitih in poškodovanih proteinov ter drugih signalnih molekul, ki nastanejo tekom različnih celičnih procesov.
Rančnik, Pia
core  

UEG Week 2024 Moderated Posters

United European Gastroenterology Journal, Volume 12, Issue S8, Page 201-664, October 2024.
wiley   +1 more source

LMP2 ve LMP7 genlerinin obezite ile ı̇lişkisinin ı̇ncelenmesi

, 2020
67
openaire   +1 more source

Efficiency of bacterial killing is unaltered in β5i/LMP7^-/- leukocytes.

, 2016
(A) Analysis of phagocytosis of fluorochrome-labelled particles by BMM, determined by flow cytometry (each group with n = 3). (B) Analysis of the intracellular early phase of killing and (C) late phase of killing of D39Δcps by BMM. Therefore, BMM were co-
Peter-Michael Kloetzel (410911), Martin Witzenrath (167419), Felicia Kirschner (2622049), Katrin Reppe (599647), Nadine Andresen (2622046), Frédéric Ebstein (528304)   +5 more
core   +1 more source