Results 91 to 100 of about 2,385 (193)

A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus.

PLoS ONE, 2011
Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a β-Herpesvirus that infects the majority of the world's population and causes disease in neonates and immunocompromised adults.
Sarah Hutchinson, Stuart Sims, Geraldine O'Hara, Jon Silk, Uzi Gileadi, Vincenzo Cerundolo, Paul Klenerman   +6 more
doaj   +1 more source

Expression of genes coding for β-catenin, CacyBP/SIP, galectin-3 and LMP7 in men hearts (mean ± SE).

, 2020
The correlation between expression of gene coding for β-catenin, CacyBP/SIP, galectin-3, LMP7 and individual’s age.
Irena Kasacka (8520003), Wojciech Łebkowski (8520015), Żaneta Piotrowska (8520006), Alicja Lewandowska (8520012), Michał Niezgoda (8520009)   +4 more
core   +1 more source

Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models

Lipids in Health and Disease, 2011
Background Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases.
Papasian Christopher J, Badr Mostafa Z, Reis Julia C, Tan Xiaoyu, Qureshi Asaf A, Morrison David C, Qureshi Nilofer   +6 more
doaj   +1 more source

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis.

, 2010
BACKGROUND AND AIMS: Inflammatory bowel disease (IBD), comprising Crohn s disease and ulcerative colitis, is characterised by chronic relapsing inflammation of the gut.
Schmidt, N;Gonzalez, E;Visekruna, A;Kuhl, AA;Loddenkemper, C;Mollenkopf, H;Kaufmann, SH;Steinhoff, U;Joeris, T
core   +1 more source

ASOCIACIÓN DE LOS POLIMORFISMOS LMP2 rs17587 Y LMP7 rs2071543 EN TEJIDOS DE PACIENTES CON LINFOMAS HODGKIN Y NO HODGKIN INFECTADOS POR EL VIRUS DE EPSTEIN BARR

, 2022
Introducción: El virus de Epstein Barr (VEB) tiene una distribución mundial, presenta alto potencial oncogénico celular, manipulando las vías de crecimiento, supervivencia y diferenciación de las células B de manera predominante, con progresión a ...
Jaime Palomares-Marin (12867511), Jesús Morales-Martínez (12867540), Iván Isidro Hernández-Cañaveral (12867551), Karel César Licona-Lasteros (12867491), Ramón Franco-Topete (5836217), Gerardo Cazarez-Navarro (12867536), Sergio Yair Rodríguez Preciado (12867548)   +6 more
core   +1 more source

Replacement of proteasome subunits X and Y by LMP7 and LMP2 induced by interferon-γ for acquirement of the functional diversity responsible for antigen processing [PDF]

, 1994
Proteasomes catalyze the non-lysosomal, ATP-dependent selective breakdown of ubiquitinated proteins and are thought to be responsible for MHC class I-restricted antigen presentation.
Hendil, Klaus B., Kinya Akiyama, Klavs B. Hendil, Kagawa, S., Tanaka, K., Kagawa, Susumu, Shimbara, Naoki, Ichihara, A., Takashina, Makoto, Tamura, Tomohiro, Akiyama, K., Poul Kristensen, Susumu Kagawa, Naoki Shimbara, Akira Ichihara, Tomohiro Tamura, Takashima, M., Hendil, Klavs B., Tanaka, Keiji, Kristensen, Poul, Keiji Tanaka, Akiyama, Kinya, Shimbara, N., Ichihara, Akira, Makoto Takashina   +24 more
core   +1 more source

Expression of immune subunits LMP2 and LMP7 in cytokeratin 18 containing cells of IDC sample.

, 2014
(Panels A) Mouse mAbs to cytokeratin 18, rabbit pAbs to LMP2. (Panels B) Mouse mAbs to cytokeratin 18, rabbit pAbs to LMP7. IDC, invasive ductal carcinoma. Scale bar, 100 µm.
Elena M. Slonimskaya (646538), Irina V. Kondakova (646542), Olga V. Savenkova (646539), Nikolay G. Gornostaev (646541), Alexey M. Kulikov (646540), Yulia V. Lyupina (646536), Elena E. Shashova (646535), Svetlana A. Glushchenko (646537), Natalia P. Sharova (646543)   +8 more
core   +1 more source

Relationship between age and intensity of immunohistochemical reaction in the man’s heart: Immunoreaction against β-catenin in intercalated discs (A), immunoreaction against β-catenin in cardiomyocytes cytoplasm (B), immunoreaction against CacyBP/SIP in cardiomyocytes (C), immunoreaction against galectin-3 in cardiomyocytes (D) immunoreaction against LMP7 in cardiomyocytes (E), immunoreaction against LMP7 in the interstitial cells (F).

, 2020
Relationship between age and intensity of immunohistochemical reaction in the man’s heart: Immunoreaction against β-catenin in intercalated discs (A), immunoreaction against β-catenin in cardiomyocytes cytoplasm (B), immunoreaction against CacyBP/SIP in ...
Irena Kasacka (8520003), Wojciech Łebkowski (8520015), Żaneta Piotrowska (8520006), Alicja Lewandowska (8520012), Michał Niezgoda (8520009)   +4 more
core   +1 more source

Sequences, annotation and single nucleotide polymorphism of the major histocompatibility complex in the domestic cat.

PLoS ONE, 2008
Two sequences of major histocompatibility complex (MHC) regions in the domestic cat, 2.976 and 0.362 Mbps, which were separated by an ancient chromosome break (55-80 MYA) and followed by a chromosomal inversion were annotated in detail.
Naoya Yuhki, James C Mullikin, Thomas Beck, Robert Stephens, Stephen J O'Brien   +4 more
doaj   +1 more source

Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 (beta 1i), MECL1 (beta 2i) and LMP7 (beta 5i)

, 2008
Objectives. Autoantibodies against the 20S-proteasome display a broad diversity with a remarkably low frequency of individual cross-reactivity against the different subunits of the proteasome. Although their pathogenic and diagnostic significance remains
Egerer, K., Feist, E., Scheffler, S., Reiter, K., Soza, A., Burmester, G. R., Kuckelkorn, U., Doerner, T.   +7 more
core   +1 more source