Results 81 to 90 of about 2,423 (198)
Heat Shock Up-Regulates lmp2 and lmp7 and Enhances Presentation of Immunoproteasome-Dependent Epitopes [PDF]
The Journal of Immunology, 2006 Abstract The heat shock response is a canonical regulatory pathway by which cellular stressors such as heat and oxidative stress alter the expression of stress-responsive genes. Some of these stress-responsive genes (heat shock proteins and MHC class I (MHC I)-related chains) play a significant role in the immune system. In this study,
Margaret K, Callahan +3 more
openaire +2 more sources
Expression of immune subunits LMP2 and LMP7 in cytokeratin 18 containing cells of IDC sample.
, 2014 (Panels A) Mouse mAbs to cytokeratin 18, rabbit pAbs to LMP2. (Panels B) Mouse mAbs to cytokeratin 18, rabbit pAbs to LMP7. IDC, invasive ductal carcinoma. Scale bar, 100 µm.
Elena M. Slonimskaya (646538) +8 more
core +1 more source
, 2020 Relationship between age and expression of genes coding β-catenin (CTNNB1) (A), CacyBP/SIP (B), galectin-3 (LGALS3) (C) and LMP7 (PSMB8) (D) in the men heart.
Irena Kasacka (8520003) +4 more
core +1 more source
Expression of Immunoproteasome Subunit LMP7 in Breast Cancer and Its Association with Immune-Related Markers [PDF]
Cancer Research and Treatment, 2019 In the presence of interferon, proteasome subunits are replaced by their inducible counterparts to form an immunoproteasome (IP) plays a key role in generation of antigenic peptides presented by MHC class I molecules, leading to elicitation of a T cell‒mediated immune response.
Lee, Miseon +8 more
openaire +2 more sources
Clinical and Translational Medicine, Volume 14, Issue 12, December 2024.CircHipk3‐mediated macrophage pyroptosis acts as a critical upstream regulator of inflammatory cytokines and matrix metalloproteinases (MMPs), significantly contributing to abdominal aortic aneurysm (AAA) formation and rupture. CircHipk3 enhances NLRP3 inflammasome activation by interacting with Stat3 and degrading Ptbp1 mRNA, thereby inhibiting ...
Donghua Cai +8 more
wiley +1 more source
Role of immunoproteasomes in cross-presentation. [PDF]
, 2006 The evidence that proteasomes are involved in the processing of cross-presented proteins is indirect and based on the in vitro use of proteasome inhibitors.
Uzi Gileadi +10 more
core +1 more source
Nomenclature for Factors of the HLA System, 2026
HLA, Volume 107, Issue 3, March 2026.
Steven G. E. Marsh +14 more
wiley +1 more source
Scientific Reports, 2017 Merkel cell carcinoma (MCC) is a rare and aggressive, yet highly immunogenic skin cancer. The latter is due to its viral or UV-associated carcinogenesis. For tumor progression MCC has to escape the host’s immuno-surveillance, e.g.
Cathrin Ritter +8 more
doaj +1 more source
Recent Developments and Evolving Therapeutic Strategies in KMT2A‐Rearranged Acute Leukemia
Cancer Medicine, Volume 13, Issue 20, October 2024.ABSTRACT Background Rearrangements of the histone‐lysine‐N‐methyltransferase (KMT2A), previously referred to as mixed‐lineage leukemia (MLL), are among the most common chromosomal abnormalities in patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), involving numerous different fusion partners.
Lei Yin +4 more
wiley +1 more source
Resistance of LMP7-deficient mice to infection with P. yoelii.
, 2013 (A) Parasitemia (two left panels) and survival ratio (right panel) was monitored in the indicated mice infected with PyL. Each symbol represents parasitemia from an individual mouse, and the numbers or “s” represent day of mouse death or mice survival ...
Makoto Hirai (227542) +10 more
core +1 more source