Results 11 to 20 of about 33,666 (150)

LncRNA XIST promotes neovascularization in diabetic retinopathy by regulating miR-101-3p/VEGFA [PDF]

Archives of Endocrinology and Metabolism
Objective: This study sought to investigate the regulation of long noncoding RNA (lncRNA) XIST on the microRNA (miR)-101-3p/vascular endothelial growth factor A (VEGFA) axis in neovascularization in diabetic retinopathy (DR).
Weina Fu, Yunyan Ye, Feng Hu
doaj   +3 more sources

Effect of lncRNA XIST on acute myeloid leukemia cells via miR-142-5p-PFKP axis

Hematology
Acute myeloid leukemia (AML) is the common blood cancer in hematopoietic system-related diseases and has a poor prognosis. Studies have shown that long non-coding RNAs (lncRNAs) are closely related to the pathogenesis of a variety of diseases, including ...
Zhaozhi Jiang, Tingting Liu, Youhong Wang, Jiao Li, Lusheng Guo   +4 more
exaly   +4 more sources

lncRNA XIST Interacts with Regulatory T Cells within the Tumor Microenvironment in Chronic Hepatitis B-Associated Hepatocellular Carcinoma [PDF]

Türk Patoloji Dergisi
Objective: Alterations in the expression of several long non-coding RNAs (lncRNAs) have been shown in chronic hepatitis B-associated hepatocellular carcinoma (CHB-HCC).
Burcin PEHLIVANOGLU, Anil AYSAL, Cihan AGALAR, Tufan EGELI, Mucahit OZBILGIN, Tarkan UNEK, Ilkay Tugba UNEK, Ilhan OZTOP, Safiye AKTAS, Ozgul SAGOL   +9 more
doaj   +3 more sources

Knockdown of lncRNA XIST Ameliorates IL-1β-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-κB Signaling Pathway

Cardiovascular Therapeutics, 2022
Background. The effect of lncRNA X inactive-specific transcript (XIST) inducing cardiovascular diseases on deep vein thrombosis (DVT) and its mechanism has not been reported.
Guangxin Cao, Hua Zhou, Dong Wang, Lei Xu   +3 more
doaj   +2 more sources

LncRNA Jpx induces Xist expression in mice using both trans and cis mechanisms. [PDF]

PLoS Genetics, 2018
Mammalian X chromosome dosage compensation balances X-linked gene products between sexes and is coordinated by the long noncoding RNA (lncRNA) Xist. Multiple cis and trans-acting factors modulate Xist expression; however, the primary competence factor ...
Sarah Carmona, Benjamin Lin, Tristan Chou, Katti Arroyo, Sha Sun   +4 more
doaj   +2 more sources

CVB3 regulates Treg cell pyroptosis through the lncRNA XIST/miR-195-5p/caspase-1 molecular axis

Immunobiology
Viral myocarditis (VMC) is characterized by severe cardiac inflammation and is a major cause of congestive heart failure and sudden cardiac death in healthy young people.
Yan Zhang, Lei Yang, Huiting Mu, Na Li, Xuejia Wang, Hualan Lei, Mingjie Pang   +6 more
doaj   +2 more sources

LncRNA XIST facilitates the odontogenic differentiation of dental pulp stem cells via the FUS/ZBTB16 [PDF]

Journal of Applied Oral Science
Objective This study aims to explore the regulatory mechanism of long noncoding RNA X inactive specific transcript (lncRNA XIST) in the odontogenic differentiation of human dental pulp stem cells (hDPSCs).
Ruiqing CHENG, Honglei SUN, Xiaotong QIAO, Xuefang CHEN   +3 more
doaj   +2 more sources

LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

Cancer Cell International, 2018
Background The abnormal expression of non-coding RNAs (ncRNAs), such as microRNAs and long ncRNAs, often contribute to the development of cancers.
Ran Xu, Xuan Zhu, Fangzhi Chen, Changkun Huang, Kai Ai, Hongtao Wu, Lei Zhang, Xiaokun Zhao   +7 more
doaj   +2 more sources

Prognostic role of long non-coding RNA XIST expression in patients with solid tumors: a meta-analysis

Cancer Cell International, 2018
Background The aberrant expression of long non-coding RNA (lncRNA) X inactivate-specific transcript (XIST) has been demonstrated to be involved in the tumourigenesis and the development of various cancers.
Huihui Mao, Kai Wang, Yuehua Feng, Jun Zhang, Lili Pan, Yuxia Zhan, Haijun Sheng, Guanghua Luo   +7 more
doaj   +2 more sources

LncRNA Xist通过调控SDF-1/CXCR4轴促进大鼠骨髓间充质干细胞增殖与迁移 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨lncRNA Xist在大鼠骨髓间充质干细胞（BMSC）增殖和迁移中的作用及其可能机制。【方法】取3周龄的雌性SD大鼠的股骨和胫骨，分离BMSC细胞，体外培养并鉴定。设计并筛选对lncRNA Xist沉默效率高的siRNA；利用Lipo2000分别将si-Xist和si-NC转染入实验组（si-Xist组）和对照组（si-NC组）BMSC中。CCK-8实验检测各组BMSC增殖能力。划痕及Transwell迁移实验检测各组BMSC横向和纵向迁移能力。qPCR验证lncRNA ...
段亚妮, 木拉提·阿比来列提, 朱雁秋, 唐镭蕾, 朱俊颖, 覃杰   +5 more
doaj   +1 more source