Results 101 to 110 of about 215,538 (386)

Roles of LncRNAs in Viral Infections [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections.
Chan Ding, Weiwei Liu
openaire   +3 more sources

Epithelial-mesenchymal transition-related genes in coronary artery disease

Open Medicine, 2022
Epithelial-mesenchymal transition (EMT) is critical in the development of coronary artery disease (CAD). However, landscapes of EMT-related genes have not been fully established in CAD.
Xu Xiang, Zou Renchao, Liu Xiaoyong, Liu Jia, Su Qianqian   +4 more
doaj   +1 more source

Study of LncRNA BANCR expression in tumor tissues and adjacent normal tissues in gastric cancer patients

Advanced Biomedical Research, 2023
Background: Long non-coding RNAs (lncRNAs) have emerged as crucial regulators in various biological processes, including cancer development and progression.
Raha Nikanfar, Rozhin Dabbaghi, Ali Rajabi, Shahriar Hashemzadeh, Behzad Baradaran, Shahram Teimourian, Reza Safaralizadeh   +6 more
doaj   +1 more source

lncRNA ZFAS1 promotes lung fibroblast-to-myofibroblast transition and ferroptosis via functioning as a ceRNA through miR-150-5p/SLC38A1 axis

Aging, 2020
Pulmonary fibrosis (PF) is a lethal fibrotic lung disease. The role of lncRNAs in multiple diseases has been confirmed, but the role and mechanism of lncRNA zinc finger antisense 1 (ZFAS1) in the progression of PF need to be elucidated further.
Yanni Yang, W. Tai, Nihong Lu, Ting Li, Yongjun Liu, Wenjuang Wu, Zhengkun Li, Lin Pu, Xiaoyuan Zhao, Tao Zhang, Zhaoxing Dong   +10 more
semanticscholar   +1 more source

Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum. [PDF]

, 2015
BackgroundPlasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging.
Bunnik, Evelien M, Le Roch, Karine G, Lonardi, Stefano, Lu, Xueqing Maggie, Nasseri, Sara, Pokhriyal, Neeti   +5 more
core   +2 more sources

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

Advanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang, Xinyu Jiang, Xiaobo Yuan, Zhipeng Zhou, Zhenwei Zhao, Longfei Wang, Wu Jiao, Wenxue Ye, Qingxin Song   +8 more
wiley   +1 more source

Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease

Journal of Integrative Neuroscience, 2023
Background: Alzheimer’s disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Lining Su, Yixuan Zhang, Yanbing Wang, Huiping Wei   +3 more
doaj   +1 more source

Targeting of polycombs to DNA in EMT [PDF]

, 2017
We here describe the conceptual advance provided by the study by Battistelli and coworkers (PMID: 27452518), that shed light on a molecular mechanism of Polycomb targeting in the biological process known as Epithelial-to-Mesenchymal Transition (EMT ...
Battistelli, Cecilia, Cicchini, Carla, Tripodi, Marco   +2 more
core   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1

Molecular Cancer, 2019
Long noncoding RNAs (lncRNAs) have emerged as critical players in cancer progression, but their functions in colorectal cancer (CRC) metastasis have not been systematically clarified.
Yingmin Wu, Xiangling Yang, Zhuojia Chen, Lin Tian, Guan-min Jiang, Feng Chen, Jiexin Li, Panpan An, Linlin Lu, Nan Luo, Jun Du, H. Shan, Huanliang Liu, Hongsheng Wang   +13 more
semanticscholar   +1 more source