Results 21 to 30 of about 103,530 (319)
The lncRNA Pnky in the Brain [PDF]
Cell Stem Cell, 2015 Long noncoding RNAs (lncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract ...
Jenny Hsieh, Kyung-Ok Cho
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Oncology Letters, 2016 Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs composed of >200 nucleotides. Recent studies have revealed that lncRNAs exert an important role in the development and progression of cancer. In this review, the involvement of the most extensively investigated lncRNAs in cancers of the digestive, respiratory, reproductive, urinary and ...
Jin‑Shui Zhu +4 more
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The Role of LncRNAs in Uveal Melanoma [PDF]
Cancers, 2021 Uveal melanoma (UM) is an intraocular cancer tumor with high metastatic risk. It is considered a rare disease, but 90% of affected patients die within 15 years. Non-coding elements (ncRNAs) such as long non-coding RNAs (lncRNAs) have a crucial role in cellular homeostasis maintenance, taking part in many critical cellular pathways.
Paula Milán-Rois +3 more
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LncRNAs and CircRNAs in cancer
MedComm, 2022 AbstractIt is well known that noncoding RNAs (ncRNAs) cannot encode proteins, but they can play important regulatory roles in tumors by combining with proteins, RNAs, and DNAs. As more and more studies reveal the important roles and underlying mechanisms of long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) in cancer, their huge application ...
Xin Yin +5 more
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Stem Cells International, 2016 Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells ...
Shanshan Hu, Ge Shan
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Research Progress of RNA Molecules in Thyroid Cancer
Zhongliu Fangzhi Yanjiu, 2019 Thyroid cancer is the most common malignant tumor in the endocrine system, accounting for about 1% of all malignant tumors. At present, it has become a hot research topic to study the pathogenesis of thyroid cancer at the level of gene DNA.
LIN Lin, LIU Jianhua, WU Li'na
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LncRNA RP1-85F18.6 affects osteoblast cells by regulating the cell cycle
Open Life Sciences, 2020 A lncRNA RP1-85F18.6 was reported to affect cell growth by regulating the cell cycle. Here we tested whether it affects the proliferation of osteoblast cells by regulating the cell cycle. We determined the expression of RP1-85F18.6 in two osteoblast cell
Song Jiangtao, Song Wenrong, Zhang Lei
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Environmental Health and Preventive Medicine, 2022 Background: This study aimed to evaluate the correlation between long non-coding RNA (lncRNA)-related single nucleotide polymorphisms (SNPs) and susceptibility to silicosis.
Wei Wang +10 more
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Journal of Hepatocellular Carcinoma, 2021 Jiamin Cheng,1,* Yinyin Li,1,* Xiaohui Wang,2,* Zheng Dong,1 Yan Chen,1 Rui Zhang,1 Jiagan Huang,1 Xueyuan Jin,1 Jianfei Yao,2 Aifang Ge,2 Lele Song,2,3,* Yinying Lu,1 Zhen Zeng1 1Comprehensive Liver Cancer Department, The Fifth Medical ...
Cheng J +12 more
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Oncotarget, 2015 Long non-coding RNAs (lncRNAs) play key roles in diverse biological processes. Moreover, the development and progression of cancer often involves the combined actions of several lncRNAs. Here we propose a multi-step method for constructing lncRNA-lncRNA functional synergistic networks (LFSNs) through co-regulation of functional modules having three ...
Zishan Wang +7 more
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