Results 21 to 30 of about 167,789 (348)
LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond
Journal of experimental & clinical cancer research : CR, 2022 DNA methylation is one of the most important epigenetic mechanisms to regulate gene expression, which is highly dynamic during development and specifically maintained in somatic cells.
Wanxu Huang +4 more
semanticscholar +1 more source
Comprehensive analysis of lncRNA expression profiles in rats with cerebral ischemia-reperfusion injury after treatment with 20(R)-ginsenoside Rg3 [PDF]
Journal of Integrative Neuroscience, 2022 This study was aimed at investigating the differentially expressions of long noncoding RNAs (lncRNAs) and mRNAs in the brains of a middle cerebral artery occlusion/reperfusion (MCAO/R) group and a MCAO/R + 20(R)-Rg3 group.
Yuan Yang +7 more
doaj +1 more source
A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma
Scientific Reports, 2022 Increased intracellular toxicity due to an imbalance in copper homeostasis caused by copper ion accumulation could regulate the rate of cancer cell growth and proliferation.
Genhao Zhang +2 more
semanticscholar +1 more source
Revealing protein–lncRNA interaction [PDF]
Briefings in Bioinformatics, 2015 Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs. The currently available knowledge is already drawing an intricate network of interactions, whose deregulation is ...
FERRE', FABRIZIO +2 more
openaire +5 more sources
Biological Function of Long Non-coding RNA (LncRNA) Xist
Frontiers in Cell and Developmental Biology, 2021 Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as
Wenlun Wang +7 more
semanticscholar +1 more source
Cell Death and Disease, 2022 Ferroptosis is a new type of cell death that has been recognized in recent years and is different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron homeostasis and lipid peroxidation of iron metabolism caused by large ...
Baofu Zhang +12 more
semanticscholar +1 more source
The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases [PDF]
Scientific Reports, 2017 AbstractWell characterized the connections among diseases, long non-coding RNAs (lncRNAs) and drugs are important for elucidating the key roles of lncRNAs in biological mechanisms in various biological states. In this study, we constructed a database called LNCmap (LncRNA Connectivity Map), available at http://www.bio-bigdata.com/LNCmap/, to establish ...
Haixiu Yang +11 more
openaire +3 more sources
Journal of Hematology & Oncology, 2022 Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu +12 more
semanticscholar +1 more source
Efficient and specific DNA oligonucleotide rRNA probe-based rRNA removal in Talaromyces marneffei
Mycology, 2022 Emerging evidence showed that lncRNAs play important roles in a wide range of biological processes of fungi such as Saccharomyces cerevisiae. However, systemic identification of lncRNAs in non-model fungi is a challenging task as the efficiency of rRNA ...
Xueyan Hu +3 more
doaj +1 more source
Annals of Urologic Oncology, 2022 Prostate cancer is most prevalent malignancy of males in the world. In recent years, long non-coding RNAs (lncRNAs) were identified, and their functions are associated with prostate cancer initiation and progression.
Hezhen Chu +5 more
doaj +1 more source