Results 31 to 40 of about 161,633 (199)

Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data

Nucleic Acids Res., 2020
An updated Lnc2Cancer 3.0 (http://www.bio-bigdata.net/lnc2cancer or http://bio-bigdata.hrbmu.edu.cn/lnc2cancer) database, which includes comprehensive data on experimentally supported long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) associated
Yue Gao, Shipeng Shang, Shuang Guo, Xin Li, Hanxiao Zhou, Hongjia Liu, Yue Sun, Junwei Wang, Peng Wang, Hui Zhi, Xia Li, Shangwei Ning, Yunpeng Zhang   +12 more
semanticscholar   +1 more source

Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model

Platelets, 2019
Platelet hyperaggregation and hypercoagulation are associated with increase of thrombogenic risk, especially in patients with type 2 diabetes (T2D).
Ming Zhou, Meng Gao, Yanwei Luo, Rong Gui, Hongwen Ji   +4 more
doaj   +1 more source

The lncRNA Neat1 promotes activation of inflammasomes in macrophages

Nature Communications, 2019
The inflammasome has an essential function in innate immune, responding to a wide variety of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several inflammasomes.
Pengfei Zhang, Limian Cao, Rongbin Zhou, Xiaolu Yang, Mian Wu   +4 more
semanticscholar   +1 more source

Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma

Oncogene, 2020
RNA methylation is an important epigenetic modification. Recent studies on RNA methylation mainly focus on the m6A modification of mRNA, but very little is known about the m5C modification.
Zhen Sun, Songlei Xue, Meiying Zhang, Hui Xu, Xuming Hu, Shihao Chen, Yangyang Liu, M. Guo, H. Cui   +8 more
semanticscholar   +1 more source

An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells

Epigenetics, 2018
Long noncoding RNAs (lncRNAs) are critical regulators of cell biology whose alteration can lead to the development of diseases such as cancer. The potential role of lncRNAs and their epigenetic regulation in response to platinum treatment are largely ...
Olga Vera, Carlos Rodriguez-Antolin, Javier de Castro, Florian A. Karreth, Thomas A. Sellers, Inmaculada Ibanez de Caceres   +5 more
doaj   +1 more source

Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer

International Journal of Molecular Sciences, 2019
Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth and metastasis.
Liye Wang, Kwang Bog Cho, Yan Li, Gabriel Tao, Zuoxu Xie, Bin Guo   +5 more
semanticscholar   +1 more source

Long noncoding RNA expression in the cervix mid-pregnancy is associated with the length of gestation at delivery

Epigenetics, 2018
Infants born preterm are at increased risk of multiple morbidities and mortality. Why some women deliver preterm remains poorly understood. Prior studies have shown that cervical microRNA expression and DNA methylation are associated with the length of ...
Heather H. Burris, Allan C. Just, Miriam J. Haviland, Dayna T. Neo, Andrea A. Baccarelli, Alexandra E. Dereix, Kasey J. Brennan, Rodosthenis S. Rodosthenous, Steven J. Ralston, Jonathan L. Hecht, Michele R. Hacker   +10 more
doaj   +1 more source

LncRNA-Encoded Peptide: Functions and Predicting Methods

Frontiers in Oncology, 2021
Long non-coding RNA (lncRNA) was originally defined as the representative of the non-coding RNAs and unable to encode. However, recent reports suggest that some lncRNAs actually contain open reading frames that encode peptides. These coding products play
Jiani Xing, Haizhou Liu, Wei Jiang, Lihong Wang   +3 more
semanticscholar   +1 more source

The roles of miRNA, lncRNA and circRNA in the development of osteoporosis

Biological Research, 2020
Osteoporosis is a common metabolic bone disease, influenced by genetic and environmental factors, that increases bone fragility and fracture risk and, therefore, has a serious adverse effect on the quality of life of patients.
Yang Yang, Yujiao Wang, Wang Fang, Linhui Yuan, Guo Ziqi, Zhichen Wei, Wang Zirui, Shengwang Wang   +7 more
semanticscholar   +1 more source

Analysis of lcnRNAHomebox transcript antisense RNA (HOTAIR) expression in Polish women with endometriosis

Archives of Medical Science, 2023
Introduction Long non-coding RNAs (lncRNAs) are implicated in endometriosis development. The aim of the study was to analyse the expression of lncRNA HOTAIR in the context of the risk of developing endometriosis. Material and methods The presented study
Tomasz Szaflik, Hanna Romanowicz, Dariusz Trzmielak, Marianna Makowska, Beata Smolarz   +4 more
doaj   +1 more source