Results 71 to 80 of about 215,538 (386)
LncRNAs in ocular neovascularizations
International Journal of Ophthalmology, 2019 The prevalence of eye diseases worldwide is dramatically increasing and represents a major concern in underdeveloped and developed regions. Ocular diseases, previously associated with a higher depression risk, also impose a substantial economic burden on affected families, thus early detection and/or accurate treatment in order to avoid and prevent ...
Min-Ting Chen, Yacouba Cissé, Lang Bai
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Beyond the RNA-dependent function of LncRNA genes
eLife, 2020 While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, the focus regarding their mechanisms of action has been primarily on the RNA product of these genes. Recent work on several lncRNAs genes demonstrates that not
Tamer Ali, Phillip Grote
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Divergent lncRNAs take the lead on pluripotent cell differentiation [PDF]
, 2016 [No abstract ...
Ballarino, Monica, Rosa, Alessandro
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LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
Virus Research, 2018 Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements.
Linlin Chen, Hongjun Li, Yan Zhou
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Archives of Medical Science, 2023 Introduction Long non-coding RNAs (lncRNAs) are implicated in endometriosis development. The aim of the study was to analyse the expression of lncRNA HOTAIR in the context of the risk of developing endometriosis. Material and methods The presented study
Tomasz Szaflik +4 more
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The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation [PDF]
, 2018 The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers.
A Busanello +51 more
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Cancer Management and Research, 2020 Zhiyuan Xu,1,* Hang Lv,2,* Yiping Wang,2 Can Hu,3 Shangqi Chen,3 Yian Du,1 Chengwei Shi,3 Xiangdong Cheng1 1Department of Gastric Surgery, Institute of Cancer and Basic Medicine, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang ...
Xu Z +7 more
doaj
Molecular Cancer, 2019 Hepatocellular carcinoma (HCC) is the most common malignant liver tumor with poor clinical outcomes. Increasing amount of long non-coding RNAs (lncRNAs) have been revealed to be implicated in the carcinogenesis and progression of HCC.
Yufeng Wang +10 more
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The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. [PDF]
, 2019 A major challenge in finding a cure for HIV-1/AIDS is the difficulty in identifying and eradicating persistent reservoirs of replication-competent provirus.
Chang, Kungyen +11 more
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The lncRNA epigenetics: The significance of m6A and m5C lncRNA modifications in cancer
Frontiers in Oncology, 2023 Most of our transcribed RNAs are represented by non-coding sequences. Long non-coding RNAs (lncRNAs) are transcripts with no or very limited protein coding ability and a length >200nt. They can be epigenetically modified. N6-methyladenosine (m6A), N1-methyladenosine (m1A), 5-methylcytosine (m5C), 7-methylguanosine (m7G) and 2’-O-methylation (Nm)
Vincenza Ylenia Cusenza +3 more
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