Results 111 to 120 of about 33,716 (178)

Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR. Transient transfection technique was used to overexpress XIST in MCF-7 cells.
HOU Xia, ZHOU Yongan, TIAN Shuxiong, LI Chao, LI Min, REN Ruirui, HAN Yaxin, CHENG Jianping, LI Xingxing, LI Zhe, BAI Yuan   +10 more
openaire   +1 more source

Transcriptional stochasticity reveals multiple mechanisms of long non-coding RNA regulation at the Xist–Tsix locus

Nature Communications
Long noncoding RNAs (LncRNAs) are increasingly recognized as being involved in human physiology and diseases, but there is a lack of mechanistic understanding for the majority of lncRNAs.
Benjamin K. Kesler, John Adams, Gregor Neuert   +2 more
doaj   +1 more source

Prevalence of Diabetic Kidney Disease with Different Subtypes in Hospitalized Patients with Diabetes and Correlation Between eGFR and LncRNA XIST Expression in PBMCs. [PDF]

Diabetes Ther, 2023
Lin Y, Wu P, Guo L, Feng Q, Wang L, Lin X, Yang C, Liu N, Wen C, Li X, Ma X, Xue Y, Guan M.   +12 more
europepmc   +1 more source

Wenshen Yiqi Granule Alleviates Chronic Obstructive Pulmonary Disease via the Long Noncoding RNA‐XIST/MicroRNA‐200c‐3p Axis

Pulmonary Circulation
Chronic obstructive pulmonary disease (COPD) is a major challenge to global public health. Evidence showed that long noncoding RNA (lncRNA)‐XIST/microRNA (miRNA)‐200c‐3p axis regulated apoptosis and inflammation in cigarette smoke extract (CSE)‐exposed ...
Haoran Deng, Shiping Zhu, Fei Yu, Xue Song, Xinlai Jin, Xuchun Ding   +5 more
doaj   +1 more source

lncRNA XIST inhibition promotes M2 polarization of microglial and aggravates the spinal cord injury via regulating miR-124-3p / IRF1 axis. [PDF]

Heliyon, 2023
Yang J, Gong Z, Dong J, Bi H, Wang B, Du K, Zhang C, Chen L.   +7 more
europepmc   +1 more source

Correction to: Prevalence of Diabetic Kidney Disease with Different Subtypes in Hospitalized Patients with Diabetes and Correlation Between eGFR and LncRNA XIST Expression in PBMCs. [PDF]

Diabetes Ther, 2023
Lin Y, Wu P, Guo L, Feng Q, Wang L, Lin X, Yang C, Liu N, Wen C, Li X, Ma X, Xue Y, Guan M.   +12 more
europepmc   +1 more source

Remodeling of XIST regulatory landscape during primate evolution

International audienceUnraveling how gene regulations are remodeled during evolution is central to understanding how biological processes evolve. We explored this question in the frame of X-chromosome inactivation, a process under strong selective ...
Castel, Gaël, Morey, C\ue9line, Heard, Edith, Rognard, Clo\ue9, Loda, Agnese, Rougeulle, Claire, Rognard, Cloé, Savatier, Pierre, Cazottes, Emmanuel, Villacorta, Laura, Dong, Michael, Castel, Ga\uebl, Alfeghaly, Charbel, Aksoy, Ir\ue8ne, Aksoy, Irène, Necsulea, Anamaria, Morey, Céline   +16 more
core   +1 more source

LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling. [PDF]

Oncogene, 2023
Ma Y, Zhu Y, Shang L, Qiu Y, Shen N, Wang J, Adam T, Wei W, Song Q, Li J, Wicha MS, Luo M.   +11 more
europepmc   +1 more source

lncRNA XIST/miR‑129‑2‑3p axis targets CCP110 to regulate the proliferation, invasion and migration of endometrial cancer cells. [PDF]

Exp Ther Med, 2023
Chen S, Liang Y, Shen Y, Wang X.
europepmc   +1 more source

How does the Xist activator Rlim/Rnf12 regulate Xist expression?

The long non-coding RNA (lncRNA) Xist is crucially involved in a process called X chromosome inactivation (XCI), the transcriptional silencing of one of the two X chromosomes in female mammals to achieve X dosage compensation between the sexes.
Mehta, Poonam, Bach, Ingolf, Wang, Feng
core   +1 more source