Results 101 to 110 of about 33,716 (178)

X-inactive-specific transcript of peripheral blood cells is regulated by exosomal Jpx and acts as a biomarker for female patients with hepatocellular carcinoma

Therapeutic Advances in Medical Oncology, 2017
Background: Long noncoding ribonucleic acid (lncRNA) X-inactive-specific transcript (Xist) was reported to affect cell proliferation and metastasis in hepatocellular carcinoma (HCC).
Xiang Ma, Tingdong Yuan, Chao Yang, Zusen Wang, Yunjin Zang, Liqun Wu, Likun Zhuang   +6 more
doaj   +1 more source

Functional Characterization of Human LncRNA JPX [PDF]

, 2019
OF THE DISSERTATIONFunctional Characterization of Human LncRNA JPXByHeather KarnerDoctor of Philosophy in Biological SciencesUniversity of California, Irvine, 2019Assistant Professor Sha Sun, Chair Long noncoding RNAs are present in all eukaryotes, but ...
Karner, Heather
core   +1 more source

Developing a ceRNA-based lncRNA-miRNA-mRNA regulatory network to uncover roles in skeletal muscle development

Frontiers in Bioinformatics
The precise role of lncRNAs in skeletal muscle development and atrophy remain elusive. We conducted a bioinformatic analysis of 26 GEO datasets from mouse studies, encompassing embryonic development, postnatal growth, regeneration, cell proliferation ...
Wang Wenlun, Wang Wenlun, Yu Chaohang, Huang Yan, Li Wenbin, Zhou Nanqing, Hu Qianmin, Wu Shengcai, Yuan Qing, Yu Shirui, Zhang Feng, Zhu Lingyun   +11 more
doaj   +1 more source

Subtype-specific lncRNA signatures: MALAT1 and XIST in breast cancer

Demiroglu Science University Florence Nightingale Journal of Medicine
Objectives: The objective of this study was to assess and compare metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and X-inactive specific transcript (XIST) expression among breast cancer molecular subtypes in vitro, and to evaluate their potential association with subtype-specific biological characteristics. Materials and methods: The
openaire   +1 more source

Xist ribonucleoproteins promote female sex-biased autoimmunity

Autoimmune diseases disproportionately affect females more than males. The XX sex chromosome complement is strongly associated with susceptibility to autoimmunity.
Goldman, Daniel W.,, Sjöberg, Ronald, Chung, Lorinda S.,, Srinivasan, Suhas, Chang, Sarah, Sjöberg, Ronald,, Wutz, Anton,, Casey, Kerriann M., Belk, Julia A., Chang, Howard Y.,, Li, Rui,, Kraft, Katerina,, Chang, Sarah,, Feng, Allan, Chung, Lorinda S., Casey, Kerriann M.,, Srinivasan, Suhas,, Käller Lundberg, Emma,, Zhao, Yanding,, Petri, Michelle, Feng, Allan,, Zhao, Yanding, Dou, Diana R.,, Abe, Brian T.,, Hellström, Cecilia,, Petri, Michelle,, Chen, Derek C., Dou, Diana R., Fiorentino, David F.,, Utz, Paul J.,, Yu, Bingfei,, Abe, Brian T., Zhao, Yang,, Shah, Ami A.,, Goldman, Daniel W., Chen, Derek C.,, Li, Rui, Hellström, Ceke, Yu, Bingfei, Shah, Ami A., Belk, Julia A.,, Kraft, Katerina, Wutz, Anton, et al.   +43 more
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Identification of a Xist silencing domain 1 by Tiling CRISPR [PDF]

, 2019
Despite the essential roles of long noncoding RNAs (lncRNAs) in development and disease, methods determine lncRNA cis-elements are lacking. Here, we developed a screening method named “Tiling CRISPR” to identify lncRNA functional domains.
Wang, Yang, Zhong, Yang, Zhou, Yingyao, Tanaseichuk, Olga, Wilkinson, Jeremy, Li, Zhizhong, Zhao, Jing Crystal   +6 more
core  

Transcription Factor ETS1 Promotes Glioma Cell Growth by Activating LncRNA XIST

Zhongliu Fangzhi Yanjiu
Objective To explore the biological function and downstream mechanism of ETS1 in glioma. Methods Bioinformatics and immunohistochemistry were used to analyze the differential expression characteristics of ETS1 in gliomas; qRT-PCR was employed to detect ...
LUO Ran, LUO Wenyi, LU Mingkai, ZHOU Meng, LIU Yanting, TIAN Chunlei   +5 more
doaj   +1 more source

LncRNA-seq data

, 2019
The statistical analysis on lncRNA transcriptome revealed that several lncRNAs are differentially expressed between RBM3-overexpressing and control ...
Lei Wang (6656), Bin-Feng Cheng (693876), Mian Wang (153332), Wei-Dong Li (223291), Hai-Jie Yang (7304588), Xin Yuan (174619), Shuang-Ping Ma (5167160), Bing-Bing Lei (7304866)   +7 more
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Emodin Regulates lncRNA XIST/miR-217 Axis to Protect Myocardial Ischemia-Reperfusion Injury. [PDF]

Oxid Med Cell Longev, 2023
Huang S, Xue L, Mou Q.
europepmc   +1 more source

Long Noncoding RNA XIST Promotes Osteosarcoma Progression by Targeting Ras-Related Protein RAP2B via miR-320b

, 2018
Abnormal expression of long noncoding RNAs (lncRNAs) often contributes to the unrestricted growth and invasion of cancer cells. lncRNA X-inactive specific transcript (XIST) expression is upregulated in several cancers; however, its underlying mechanism ...
Gong-Yi Lv, Xiao-Lin Zhang, Jun Miao
core   +1 more source