Results 141 to 150 of about 33,716 (178)

lncRNA XIST induces Aβ accumulation and neuroinflammation by the epigenetic repression of NEP in Alzheimer’s disease

open access: yesJournal of Neurogenetics, 2022
Alzheimer’s disease (AD) is the leading cause of dementia globally, but effective treatment is lacking. We aimed to explore lncRNA XIST role in AD and the mechanisms involved in the effect of changes in lncRNA XIST on the expression of Aβ-degrading ...
Cheng Chang
exaly   +4 more sources
Some of the next articles are maybe not open access.

Related searches:

The Role of LncRNA XIST in Gynecologic Cancers

Current Cancer Therapy Reviews, 2023
Abstract: Long non-coding RNAs (lncRNAs) are non-coding RNAs longer than 200 nucleotides that act by targeting translational and post-translational modifications, epigenetic regulators, and chromatin remodeling complexes. There has been increasing evidence that the lncRNA X-inactive specific transcript (lncRNA Xist) via targeting miRNAs and ...

exaly   +2 more sources

3D genomic regulation of lncRNA and Xist in X chromosome

Seminars in Cell and Developmental Biology, 2019
Long noncoding RNAs (lncRNAs) act as important regulators in cardiovascular diseases, neural degenerative disease, or cancers, by localizing and spreading across chromatins. lncRNA can regulate the 3D architecture of the enhancer cluster at the target gene locus, relevant to analogous lncRNA-protein coding gene pairs.
Yi-Ming Zeng
exaly   +3 more sources

LncRNA Xist, X-chromosome Instability and Alzheimer’s Disease

Current Alzheimer Research, 2020
Neurodegenerative Diseases (NDD) are the major contributors to age-related causes of mental disability on a global scale. Most NDDs, like Alzheimer’s Disease (AD), are complex in nature - implying that they are multi-parametric both in terms of heterogeneous clinical outcomes and underlying molecular paradigms.
Debashis Mukhopadhyay, Kaushik Chanda
exaly   +3 more sources

Home - About - Disclaimer - Privacy