Results 161 to 170 of about 33,716 (178)

LncRNA XIST: A Breakthrough in Inflammation-related Diseases

Current Medicinal Chemistry
Background: Long non-coding RNA (LncRNA) is a type of non-coding RNA that plays an important role in the body and accounts for the majority of RNA, and this non-coding RNA can regulate disease onset and progression with its wide range of functions. LncRNA Xist, also known as the long non-coding RNA X inactive specific transcript, is a member of them ...
Hailin, Wang, Lijun, Wang, Yiyang, Luo, Yibei, Gui, Wei, Wu, Jiale, Zhao, Xueqing, Li, Ruisi, Xiong, Yumin, He, Ding, Yuan, Chengfu, Yuan   +10 more
exaly   +3 more sources

LncRNA XIST regulates myocardial infarction by targeting miR‐130a‐3p

Journal of Cellular Physiology, 2018
AbstractThe study was used to probe long noncoding RNA X‐inactive specific transcript (lncRNA XIST) RNA expression profile and its influence on cell cycle, proliferation, and apoptosis in myocardial cells. We also aimed to explore the possible meditating relationship between XIST, PDE4D, and miR‐130a‐3p. Gene differential analysis was carried out using
Tao Zhou, Guowei Qin, Liehong Yang, Daokang Xiang, Suining Li   +4 more
openaire   +2 more sources

miR‐142‐5p protects against osteoarthritis through competing with lncRNA XIST

The Journal of Gene Medicine, 2020
AbstractBackgroundThe relevance between abnormal microRNA expression and osteoarthritis (OA) has been elaborated in recent studies. Hence, the present study aimed to assess the impact of miR‐142‐5p on chondrocyte growth and apoptosis.MethodsTo mimic OA‐like chondrocyte damage, interleukin (IL)‐1β was used for chondrocyte treatment.
Pengfei Sun, Yunpeng Wu, Xuezhou Li, Yuhua Jia   +3 more
openaire   +2 more sources

LncRNA XIST Promotes Pancreatic Cancer Proliferation Through miR‐133a/EGFR

Journal of Cellular Biochemistry, 2017
ABSTRACTAccording to recent studies, long non‐coding RNA X‐inactive specific transcript (XIST) is involved in the development and progression of many malignant tumors including pancreatic cancer. We validated the detailed role of XIST in human pancreatic cancer (PC) cell lines and PC tissues so as to determine its exact function and the mechanism by ...
Wei Wei, Yu Liu, Yebin Lu, Bo Yang, Ling Tang   +4 more
openaire   +2 more sources

Clinical significance of lncRNA XIST expression in cholangiocarcinoma and its effect on cell migration and invasion

Clinics and Research in Hepatology and Gastroenterology
Cholangiocarcinoma is a malignant tumor that occurs in the bile duct system, and the prognosis of patients is poor. Currently, research suggests that long non-coding RNAs (lncRNAs) in the treatment and prevention of cholangiocarcinoma. This study primarily focuses on the regulation and potential mechanism of the lncRNA XIST (XIST) in cholangiocarcinoma.
Chenxi Li, Yifei Dong, Yichuan Zhang, Caihong Wu   +3 more
openaire   +2 more sources

lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration

Molecular Therapy - Nucleic Acids, 2021
Minjie Wei, Miao He, Lin Zhao
exaly  

Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist

Phytomedicine, 2022
Yu Wang, Yu He, Bo Jin
exaly  

lncRNA XIST knockdown suppresses hypoxia/reoxygenation (H/R)‐induced apoptosis of H9C2 cells by regulating miR‐545‐3p/G3BP2

IUBMB Life, 2021

exaly  

High Expression of LncRNA XIST as an Index Helping to Diagnose Parkinson’s Disease

Neurophysiology, 2022
L. Zhang, G. Li, D. Lu, Q. Dai
openaire   +1 more source

Faculty Opinions recommendation of Challenges and perspectives for structural biology of lncRNAs-the example of the Xist lncRNA A-repeats.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2020
openaire   +1 more source