Results 31 to 40 of about 31,890 (261)

The Gilmorehill Mystery: A Location-Based Game for Campus Exploration [PDF]

open access: yes, 2021
The University of Glasgow accommodates a large number of new students every year. Arriving at a new campus can seem daunting at first, as it is always a challenge to navigate a university’s many buildings and pathways. Although in-person and self-guided online campus tours are currently offered by the University, in-person tours require advance booking
Kieran Swedlund, Matthew Barr
openaire   +1 more source

Design Framework for Social Interaction with Location-based Games

open access: yesInternational Journal of Serious Games, 2022
Location-based games invite players to have new forms of meaningful social interactions with others and provide opportunities for players to engage with their own neighbourhood’s public space.
Xavier Fonseca   +2 more
doaj  

Design of a Mobile Augmented Reality Platform with Game-Based Learning Purposes

open access: yesInformation, 2020
Augmented reality (AR) is an emergent technology that overlays virtual objects into the real environment. Lately, AR is gaining prominence in education because of its increasing affordability through computers or mobile technologies.
Maria Cristina Costa   +2 more
doaj   +1 more source

Promoting Navigation Health Literacy at the Intersection of Schools and Communities. Development of the Game-Based Intervention Nebolus

open access: yesFrontiers in Public Health, 2021
Emerging empirical evidence indicates a limited health literacy for a substantial proportion of children and adolescents. Although it is generally agreed upon promoting health literacy as early as possible in the lifespan, there is a lack of ...
Kevin Dadaczynski   +5 more
doaj   +1 more source

A Game of Pawns [PDF]

open access: yesLogical Methods in Computer Science
We introduce and study pawn games, a class of two-player zero-sum turn-based graph games. A turn-based graph game proceeds by placing a token on an initial vertex, and whoever controls the vertex on which the token is located, chooses its next location ...
Guy Avni   +2 more
doaj   +1 more source

Location-based Games as Exergames - From Pokémon To The Wizarding World

open access: yesInternational Journal of Serious Games, 2020
Exergames, i.e. games which aim to increase player’s physical activity, are a prominent sub-category of serious games (SGs). Recently, location-based games (LBGs) similar to Pokémon GO have gained the attention of exergame designers as they have been ...
Samuli Laato   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Analysis of wheelchair falls in team sports at the Paralympic Games: video-based descriptive comparison between the Rio 2016 and Tokyo 2020 games

open access: yesBMJ Open, 2022
Objectives To identify the fall characteristics of athletes in wheelchair rugby and wheelchair basketball during the Tokyo 2020 Paralympic Games and descriptively compare these with those of the Rio 2016 Paralympic Games.Design Cross-sectional analysis ...
Yukio Urabe   +15 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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