Results 91 to 100 of about 57,269 (250)

Pro-opiomelanocortin co-localizes with corticotropin-releasing factor in axon terminals of the noradrenergic nucleus locus coeruleus [PDF]

, 2006
We previously demonstrated that the opioid peptide, enkephalin, and corticotropin-releasing factor (CRF) are occasionally co-localized in individual axon terminals but more frequently converge on common dendrites in the locus coeruleus (LC).
Glaser, Julia D., Magtoto, Ronaldo, Reyes, Beverly A.S., van Bockstaele, Elisabeth K.   +3 more
core   +2 more sources

The futuristic manifolds of REM sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since one of its first descriptions 70 years ago, rapid eye movement sleep has continually inspired and excited new generations of sleep researchers. Despite significant advancements in understanding its neurocircuitry, underlying mechanisms and microstates, many questions regarding its function, especially beyond the early neurodevelopment ...
Liborio Parrino, Ivana Rosenzweig
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

A neural perspective on when and why trait greed comes at the expense of others [PDF]

, 2019
Depending on the point of view, conceptions of greed range from being a desirable and inevitable feature of a well-regulated, well-balanced economy to the root of all evil - radix omnium malorum avaritia (Tim 6.10).
Hewig, Johannes, Mussel, Patrick
core   +1 more source

Acute Effects of Oral Cannabinoids on Sleep and High‐Density EEG in Insomnia: A Pilot Randomised Controlled Trial

Journal of Sleep Research, EarlyView.
ABSTRACT Cannabinoids, particularly Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have gained popularity as alternative sleep aids; however, their effects on sleep architecture and next‐day function remain poorly understood. Here, in a pilot trial, we examined the effects of a single oral dose containing 10 mg THC and 200 mg CBD (THC/CBD) on ...
Anastasia Suraev, Iain S. McGregor, Danielle McCartney, Nathaniel S. Marshall, Chien‐Hui Kao, Rick Wassing, Angela L. D'Rozario, Keith K. H. Wong, Brendon J. Yee, Sheila Sivam, Richard C. Kevin, Ryan Vandrey, Christopher Irwin, Christopher J. Gordon, Delwyn Bartlett, Jonathon C. Arnold, Ronald R. Grunstein, Camilla M. Hoyos   +17 more
wiley   +1 more source

Comparing the Effect of Microinjection of Angiotensin II and Captopril to the Locus Coeruleus on Morphine Withdrawal Signs in Rat

مجله دانشکده پزشکی اصفهان, 2009
Background: Locus coeruleus is one of important involved sites in morphine withdrawal signs, contains high densities of Angiotensin II receptor binding sites.
Zohreh Azizolahi, Hojatollah Alaei, Mahmoud Hosseini, Ali Asghar Pilehvarian   +3 more
doaj  

Locus Coeruleus-Norepinephrine System: Spheres of Influence and Contribution to the Development of Neurodegenerative Diseases

Frontiers in Bioscience-Landmark
Locus coeruleus is a small bilateral nucleus in the brainstem. It is the main source of norepinephrine (noradrenaline) throughout the central nervous system (about 70% of all norepinephrine in the central nervous system), and, as shown in numerous ...
Vladimir Nikolaevich Nikolenko, Irina Dmitriyevna Borminskaya, Arina Timofeevna Nikitina, Maria Sergeevna Golyshkina, Negoriya Aliagayevna Rizaeva, Marine Valikovna Oganesyan   +5 more
doaj   +1 more source

Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football [PDF]

, 2017
IMPORTANCE: Players of American football may be at increased risk of long-term neurological conditions, particularly chronic traumatic encephalopathy (CTE).
Abdolmohammadi, Bobak, Alosco, Michael L., Alvarez, Victor E., Baugh, Christine M., Cantu, Robert C., Chaisson, Christine E., Cormier, Kerry A., Daneshvar, Daniel H., Goldstein, Lee E., Huber, Bertrand R., Katz, Douglas I., Kiernan, Patrick T., Kowall, Neil W., Kubilus, Caroline A., Martin, Brett M., McClean, Michael D., McHale, Lisa, McKee, Ann C., Mez, Jesse, Montenigro, Phillip H., Murphy, Lauren, Nowinski, Christopher J., Solomon, Todd M., Stein, Thor D., Stern, Robert A., Tripodis, Yorghos, Weuve, Jennifer   +26 more
core   +1 more source

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source

Fully automated MRI‐based analysis of the locus coeruleus in aging and Alzheimer's disease dementia using ELSI‐Net

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The locus coeruleus (LC) is linked to the development and pathophysiology of neurodegenerative diseases such as Alzheimer's disease (AD).
Max Dünnwald, Friedrich Krohn, Alessandro Sciarra, Mousumi Sarkar, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Annika Spottke, Johanna Brustkern, Michael T. Heneka, Frederic Brosseron, Falk Lüsebrink, Dorothea Hämmerer, Emrah Düzel, Klaus Tönnies, Steffen Oeltze‐Jafra, Matthew J. Betts   +23 more
doaj   +1 more source