Results 101 to 110 of about 32,095 (238)

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Gorenstein locus of minuscule Schubert varieties [PDF]

open access: yesarXiv, 2007
In this article, we describe explicitely the Gorenstein locus of all minuscule Schubert varieties. This proves a special case of a conjecture of A. Woo and A. Yong (see math.AG/0603273) on the Gorenstein locus of Schubert varieties.
arxiv  

Developing Conflict Monitoring Abilities Predict Children's Revision of an Intuitive Theory

open access: yesChild Development, EarlyView.
ABSTRACT We investigated the role of children's conflict monitoring skills in revising an intuitive scientific theory. Children aged 5 to 9 (N = 177; 53% girls, data collected in Germany from 2019‐2023) completed computer‐based tasks on water displacement, a concept prone to misconceptions.
Elfriede R. Holstein   +3 more
wiley   +1 more source

Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus

open access: yesCell Reports, 2018
Summary: Preclinical work has long focused on male animals, though biological sex clearly influences risk for certain diseases, including many psychiatric disorders.
Bernard Mulvey   +8 more
doaj  

Locus coeruleus co‐activation patterns at rest show higher state persistence in patients with dissociative seizures: A Pilot Study

open access: yesEpilepsia Open
Objective Dissociative seizures are paroxysmal disruptions of awareness and behavioral control in the context of affective arousal. Alterations in stress‐related endocrine function have been demonstrated, but the timescale of dissociation suggests that ...
Samantha Weber   +3 more
doaj   +1 more source

Locus of indeterminacy of the Prym map [PDF]

open access: yesarXiv, 2001
We provide an easy characterization for the locus of indeterminacy of the Prym map in terms of the dual graphs of stable curves. As a corollary, we show that the closure of the Fridman-Smith locus coincides with the locus of indeterminacy of the Prym map.
arxiv  

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

open access: yesCell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus

open access: yesCell Reports, 2019
Summary: Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We find that ASL is prominently expressed in the nucleus locus coeruleus (LC), the central
Shaul Lerner   +34 more
doaj  

On isotropic divisors on irreducible symplectic manifolds [PDF]

open access: yesarXiv, 2013
Let X be an irreducible symplectic manifold and L a divisor on X. Assume that L is isotropic with respect to the Beauville-Bogomolov quadratic form. We define the rational Lagrangian locus and the movable locus on the universal deformation space of the pair (X, L). We prove that the rational Lagrangian locus is empty or coincide with the movable locus.
arxiv  

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