Results 121 to 130 of about 57,269 (250)
Biochemical and Physiological Effects of Galanin in Health and Disease
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
CTE neuropathology alone is associated with dementia and cognitive symptoms
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION This studyexamined the independent contribution of chronic traumatic encephalopathy (CTE) neuropathology to symptoms. METHODS The sample included 614 brain donors with (n = 366) and without (n = 248) autopsy‐confirmed CTE. Brain donors with other major neurodegenerative disease diagnoses were excluded.
Rachael M. Layden +21 more
wiley +1 more source
The beneficial effects of meditation: contribution of the anterior cingulate and locus coeruleus [PDF]
, 2013 Nancy A. Craigmyle
openalex +1 more source
Brain and Behavior, Volume 16, Issue 1, January 2026.Dexmedetomidine at 25 µg/kg effectively reverses working and spatial memory deficits in a streptozotocin (STZ)‐induced rat model of Alzheimer's disease, restoring Y‐maze alternation and Morris Water Maze performance. Higher doses show no clear benefit, highlighting Dex‐25 as a promising neuroprotective candidate.
Mina Mohasel‐Roodi +5 more
wiley +1 more source
Nature Communications, 2018 Neurons of the locus coeruleus (LC) are implicated in attention and arousal. Here the authors use CRISPR/Cas9 to disrupt dopamine beta hydroxylase in LC neurons and see this reduces LC-evoked sleep-to-wake transitions and wake length.
Hiroshi Yamaguchi +3 more
doaj +1 more source
Effect of sensory deprivation and locus coeruleus phasic electrical stimulation following the deflection of adjacent whisker on response properties of principal whisker related-neurons in layer IV of rat barrel cortex [PDF]
Background: Barrel cortex of rodents is responsible for sensory information processing via facial whiskers. Locus coeruleus (LC), main source of cortical norepinephrine (NE), influences tactile sensory processing.
آفرینش, محمدرضا +4 more
core
AAV‐PHP.eB Peripheral Delivery and Central Expression in Cre Mice
Journal of Comparative Neurology, Volume 534, Issue 1, January 2026.Retro‐orbital injection of AAV‐PHP.eB‐FLEX‐tdTomato into four different strains of Cre mice produced various and distinct patterns of transduction efficiency and tropism across brain regions and cell types. We found many target neurons expressing tdTomato in most but not all strains, along with a low level of nonspecific (Cre‐independent) expression ...
Haidong Zhu, Joel C. Geerling
wiley +1 more source
Addiction Biology, Volume 31, Issue 1, January 2026.ABSTRACT The insular cortex (IC) is known to underlie drug seeking and relapse for multiple drug classes, yet the precise role the IC plays in opioid use disorder (OUD) remains unclear. In preclinical models of OUD, inhibition of the IC has produced conflicting results, such that in some cases the IC seems to promote opioid seeking whereas in others ...
Rachel E. Clarke +8 more
wiley +1 more source