Results 11 to 20 of about 32,095 (238)
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022 Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song +11 more
wiley +1 more source
Autism Research, Volume 15, Issue 12, Page 2250-2264, December 2022., 2022 Abstract A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response [PDR] and event‐related potential [ERP]) indices may provide meaningful ...
Yesol Kim +3 more
wiley +1 more source
Journal of Comparative Neurology, Volume 531, Issue 2, Page 314-335, February 2023., 2023 The main objective of this work was to obtain detailed information on the distribution and localization of the spexin (Spx) system in the sea bass brain. To this purpose, we first identified and characterized the spx1 gene and analyzed its expression in the central nervous system (CNS) of the European sea bass by using quantitative Real‐Time Polymerase
José A. Paullada‐Salmerón +2 more
wiley +1 more source
Glia, Volume 71, Issue 2, Page 377-390, February 2023., 2023 Main Points Aging‐related morphological changes in microglia (dystrophy) do not correlate with expression of universal senescence markers. Microglial dystrophy coincides with an aging‐related increase in microglial ferritin expression. Abstract Aging can cause morphological transformation in human microglia indicative of cell senescence, termed ...
Pauline Neumann +3 more
wiley +1 more source
PLoS Computational Biology, 2022 Apathy is a debilitating feature of many neuropsychiatric diseases, that is typically described as a reduction of goal-directed behaviour. Despite its prevalence and prognostic importance, the mechanisms underlying apathy remain controversial ...
Frank H Hezemans +14 more
doaj +1 more source
International Journal of Methods in Psychiatric Research, Volume 31, Issue 4, December 2022., 2022 Abstract Objective (1) investigate the associations of attention‐deficit/hyperactivity disorder (ADHD) with systolic and diastolic blood pressure, resting heart rate, pulse pressure (PP), physical fitness, and BMI; (2) explore whether cardiovascular risk factors and ADHD share genetic and environmental influences; (3) assess if pharmacological ...
Miguel Garcia‐Argibay +7 more
wiley +1 more source
Quantifying the contrast of the human locus coeruleus in vivo at 7 Tesla MRI.
PLoS ONE, 2019 The locus coeruleus is a small brainstem nucleus which contains neuromelanin cells and is involved in a number of cognitive functions such as attention, arousal and stress, as well as several neurological and psychiatric disorders.
Klodiana-Daphne Tona +3 more
doaj +1 more source
Modulation of physiological reflexes by pain: role of the locus coeruleus
Frontiers in Integrative Neuroscience, 2012 The locus coeruleus is activated by noxious stimuli, and this activation leads to inhibition of perceived pain. As two physiological reflexes, the acoustic startle reflex and the pupillary light reflex, are sensitive to noxious stimuli, this sensitivity,
Elemer eSzabadi
doaj +1 more source
Neural Plasticity, 2017 The locus coeruleus is connected to the dorsal hippocampus via strong fiber projections. It becomes activated after arousal and novelty, whereupon noradrenaline is released in the hippocampus.
Niels Hansen
doaj +1 more source
Nature Communications, 2022 Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Prokopis C. Prokopiou +13 more
doaj +1 more source