Results 21 to 30 of about 32,095 (238)
Attention: The grounds of self‐regulated cognition
WIREs Cognitive Science, Volume 14, Issue 1, January/February 2023., 2023 What is attention? Attention is a mechanism for canalizing information processing toward the conscious and voluntary regulation of actions, thoughts and emotions. Abstract Everyone knows what paying attention is, yet not everybody knows what this means in cognitive and brain function terms.
M. Rosario Rueda +2 more
wiley +1 more source
Acta Neuropathologica Communications, 2018 Degeneration of noradrenergic locus coeruleus neurons occurs during the prodromal phase of Parkinson’s disease and contributes to a variety of non-motor symptoms, e.g. depression, anxiety and REM sleep behavior disorder.
Martin Timo Henrich +9 more
doaj +1 more source
Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity
Acta Neuropathologica Communications, 2020 The locus coeruleus is the major source of noradrenaline to the brain and contributes to a wide range of physiological and cognitive functions including arousal, attention, autonomic control, and adaptive behaviour.
Sanne Simone Kaalund +6 more
doaj +1 more source
The geometry of spontaneous spiking in neuronal networks [PDF]
Journal of Nonlinear Science, 2012, 2011 The mathematical theory of pattern formation in electrically coupled networks of excitable neurons forced by small noise is presented in this work. Using the Freidlin-Wentzell large deviation theory for randomly perturbed dynamical systems and the elements of the algebraic graph theory, we identify and analyze the main regimes in the network dynamics ...
arxiv +1 more source
Acta Anaesthesiologica Scandinavica, Volume 67, Issue 1, Page 66-75, January 2023., 2023 Abstract Background Abnormal sleep is commonly observed in the ICU and is associated with delirium and increased mortality. If sedation is necessary, it is often performed with gamma‐aminobutyric acid agonists such as propofol or midazolam leading to an absence of restorative sleep.
Jakob Oxlund +5 more
wiley +1 more source
Hypothesis review: Alzheimer's overture guidelines
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Brain aging with ADNC and sporadic Alzheimer's disease (sAD) form a prevalent continuum unique to humans. Molecular changes affecting cell membranes, cytoskeleton, synapses, lipid and protein metabolism, energy metabolism, neuroinflammation, cell cycle, astrocytes, microglia, and blood vessels precede and occur in parallel with early ADNC; and they are
Isidro Ferrer
wiley +1 more source
Biology, 2022 Alzheimer’s disease (AD), which is characterized by extracellular accumulation of amyloid-beta peptide and intracellular aggregation of hyperphosphorylated tau, is the most common form of dementia.
Dilek Mercan, Michael Thomas Heneka
doaj +1 more source
The Locus Coeruleus Noradrenaline System in Delirium
Frontiers in Aging Neuroscience, 2021 Delirium is a brain state involving severe brain dysfunction affecting cognitive and attentional capacities. Our opinion statement review aims to elucidate the relationship between abnormal arousal and locus coeruleus (LC) activity in cognitive ...
Niels Hansen, Alina Isabel Rediske
doaj +1 more source
Neuromelanin-MRI using 2D GRE and deep learning: considerations for improving the visualization of substantia nigra and locus coeruleus [PDF]
arXiv, 2023 An optimized clinically feasible neuromelanin-MRI imaging protocol for visualising the SN and LC simultaneously using deep learning reconstruction is presented. We optimize flip-angle for optimal combined SN and LC depiction. We also experimented with combinations of anisotropic and isotropic in-plane resolution, partial vs full echoes and the number ...
arxiv
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source