Results 41 to 50 of about 57,269 (250)

Localization of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]

, 2014
The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Corteen, Nicole L, Metzger, Friedrich, Seifi, Mohsen, Swinny, Jerome D, van der Want, Johannes J   +4 more
core   +3 more sources

Locus coeruleus features are linked to vagus nerve stimulation response in drug-resistant epilepsy

Frontiers in Neuroscience
The locus coeruleus–norepinephrine system is thought to be involved in the clinical effects of vagus nerve stimulation. This system is known to prevent seizure development and induce long-term plastic changes, particularly with the release of ...
Alexandre Berger, Alexandre Berger, Alexandre Berger, Elise Beckers, Elise Beckers, Vincent Joris, Vincent Joris, Gaëtan Duchêne, Venethia Danthine, Nicolas Delinte, Nicolas Delinte, Inci Cakiroglu, Siya Sherif, Enrique Ignacio Germany Morrison, Andres Torres Sánchez, Andres Torres Sánchez, Benoit Macq, Laurence Dricot, Gilles Vandewalle, Riëm El Tahry, Riëm El Tahry   +20 more
doaj   +1 more source

Locus coeruleus complex of the family Delphinidae [PDF]

, 2018
The locus coeruleus (LC) is the largest catecholaminergic nucleus and extensively projects to widespread areas of the brain and spinal cord. The LC is the largest source of noradrenaline in the brain.
Arbelo, Manuel, Bernaldo De Quir\uf3s, Yara, Bombardi, Cristiano, Cozzi, Bruno, Fern\ue1ndez, Antonio, Herr\ue1ez, Pedro, Sacchini, Simona   +6 more
core   +2 more sources

The Locus Coeruleus Noradrenaline System in Delirium

Frontiers in Aging Neuroscience, 2021
Delirium is a brain state involving severe brain dysfunction affecting cognitive and attentional capacities. Our opinion statement review aims to elucidate the relationship between abnormal arousal and locus coeruleus (LC) activity in cognitive ...
Niels Hansen, Alina Isabel Rediske
doaj   +1 more source

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira, Buée, Luc, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles R., Hof, Patrick R., Jovanov-Milošević, Nataša, Leko, Mirjana Babić, Silva, Rohan de, Wischik, Claude M., Wray, Selina, Šimić, Goran   +11 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia

Annals of Neurology, EarlyView.
Objective Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair‐bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract.
Anna‐Sophie Hofer, Lennart H. Stieglitz, Marc Bolliger, Linard Filli, Adrian Cathomen, Romina Willi, Irina Lerch, Iris Krüsi, Melina Giagiozis, Christian Meyer, Martin Schubert, Michèle Hubli, Thomas M. Kessler, László Demkó, Christian R. Baumann, Lukas Imbach, Markus F. Oertel, Andrea Prusse, Alina Kiseleva, Luca Regli, Martin E. Schwab, Armin Curt   +21 more
wiley   +1 more source

Selective WGA uptake in the hippocampus from the locus coeruleus of DBH-WGA transgenic mice

Frontiers in Behavioral Neuroscience, 2012
We generated transgenic mice in which a transsynaptic tracer, wheat germ agglutinin (WGA), was specifically expressed in the locus coeruleus neurons under the control of the dopamine-β-hydroxylase gene promoter. WGA protein was produced in more than 95%
Susan G eWalling, Robert A.M. Brown, Nobuhiko eMIYASAKA, Yoshihiro eYoshihara, Carolyn W Harley   +4 more
doaj   +1 more source

Adrenergic signalling to astrocytes in anterior cingulate cortex contributes to pain-related aversive memory in rats

Communications Biology, 2023
Chemogenetic and optogenetic profiling in a rat model of acute pain-related unpleasantness suggests that colorectal distention-induced place aversion is mediated by locus coeruleus noradrenergic signalling to astrocytes in anterior cingulate cortex.
Zafar Iqbal, Zhuogui Lei, Aruna S. Ramkrishnan, Shu Liu, Mahadi Hasan, Mastura Akter, Yuk Yan Lam, Ying Li   +7 more
doaj   +1 more source

Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus

Frontiers in Aging Neuroscience, 2022
Chronic sleep disruption is a risk factor for Alzheimer’s disease (AD), yet mechanisms by which sleep disturbances might promote or exacerbate AD are not understood.
Henry Nick, Polina Fenik, Yan Zhu, Sigrid Veasey   +3 more
doaj   +1 more source