Results 121 to 130 of about 12,025 (204)

Inhaled treatment of COPD: a Delphi consensus statement

International Journal of COPD, 2017
Vincent Ninane,1 Jean-Louis Corhay,2 Paul Germonpré,3 Wim Janssens,4 Guy F Joos,5 Giuseppe Liistro,6 Walter Vincken,7 Sandra Gurdain,8 Evelyne Vanvlasselaer,8 An Lehouck8 1Department of Respiratory Medicine, Saint-Pierre Hospital, Universit ...
Ninane V, Corhay JL, Germonpré P, Janssens W, Joos GF, Liistro G, Vincken W, Gurdain S, Vanvlasselaer E, Lehouck A   +9 more
doaj  

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media

Respirology Case Reports, Volume 14, Issue 8, August 2026.
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri, Naoki Takemoto, Toshiya Minakata, Motohiko Suzuki, Yoshiyuki Ozawa, Hirotsugu Ohkubo   +5 more
wiley   +1 more source

Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease

International Journal of COPD, 2018
Donald P Tashkin,1 Nicholas J Gross2 1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Department of Medicine, University Medical Research LLC, Saint Francis Hospital and Medical Center, Hartford, CT, USA Abstract:
Tashkin DP, Gross NJ
doaj  

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Chemogenetic Activation of G12 Signaling Thickens the Epidermis With Enhanced Barrier Function

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
In this study, we investigated the role of G12 signaling in the epidermis using a keratinocyte‐specific chemogenetic approach. Activation of G12 signaling promoted keratinocyte differentiation and enhanced epidermal barrier function by upregulating filaggrin, claudin‐1, and ceramide.
Nozomi Kamakura, Natsumi Hirai, Kaito Arai, Yaxin Du, Toshiaki Kogame, Yusuke Ohno, Akio Kihara, Kenji Kabashima, Asuka Inoue   +8 more
wiley   +1 more source

Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau, Anders M. Grejs, Martin A. S. Meyer, Lars P. K. Andersen, Sören Möller, Simon Mølstrøm, Jacob E. Møller, Henrik Schmidt, Steffen Christensen, Jesper Kjærgaard, Christian Hassager, Bodil S. Rasmussen, Jo B. Andreasen   +12 more
wiley   +1 more source

Impact and prevention of severe exacerbations of COPD: a review of the evidence

International Journal of COPD, 2017
David MG Halpin,1 Marc Miravitlles,2 Norbert Metzdorf,3 Bartolomé Celli4 1Department of Respiratory Medicine, Royal Devon and Exeter Hospital, Exeter, UK; 2Pneumology Department, Hospital Universitari Vall d’Hebron, CIBER de Enfermedades ...
Halpin DMG, Miravitlles M, Metzdorf N, Celli B   +3 more
doaj  

Managing Asthma Well and Sustainably – Patient Perspectives Explored

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Context Asthma affects 300 million people worldwide. The widespread use of short‐acting beta2‐agonist (SABA) relievers, commonly delivered via pressurised metered dose inhalers (pMDIs), is contrary to evidence‐based guidelines. SABA overuse is associated with poor asthma control and high carbon emissions.
Imogen Le Couteur, Sean Docking, Katy Bell, Alexandra Barratt, Rebecca Haddock, Darlene Cox, Kate Wylie, Luise Kazda   +7 more
wiley   +1 more source

Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit

Journal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1394-1402, August 2026.
ABSTRACT Aim To evaluate adherence to the Sydney Children's Hospital Network (SCHN) Asthma‐Acute Management Practice Guideline in the management of paediatric patients presenting to a metropolitan emergency department (ED). Methods A cross‐sectional retrospective audit of 153 paediatric ED presentations with acute asthma between March 2023 and February
Yasmine Toufaili, Nounu Sarukkali
wiley   +1 more source

Revefenacin, a Long-Acting Muscarinic Antagonist, Does Not Prolong QT Interval in Healthy Subjects: Results of a Placebo- and Positive-Controlled Thorough QT Study. [PDF]

Clin Pharmacol Drug Dev, 2020
Borin MT, Barnes CN, Darpo B, Pendyala S, Xue H, Bourdet DL.   +5 more
europepmc   +1 more source