Results 1 to 10 of about 81,804 (294)

Long-term potentiation and long-term depression: a clinical perspective [PDF]

open access: yesClinics, 2011
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Timothy V.P. Bliss, Sam F. Cooke
doaj   +6 more sources

Long-Term Potentiation: The Accidental Discovery. [PDF]

open access: yesHippocampus
ABSTRACTLong‐term potentiation (LTP), is a type of synaptic plasticity now considered essential for learning and memory. Here I tell the story of how I accidentally discovered in 1966 in the laboratory of Per Andersen in Oslo, Norway, because I was not looking for it. It just emerged.
Lømo T.
europepmc   +3 more sources

The Pathway-Selective Dependence of Nitric Oxide for Long-Term Potentiation in the Anterior Cingulate Cortex of Adult Mice [PDF]

open access: yesBiomedicines
Nitric oxide (NO) is a key diffusible messenger in the mammalian brain. It has been proposed that NO may diffuse in retrograde into presynaptic terminals, contributing to the induction of hippocampal long-term potentiation (LTP).
Qi-Yu Chen   +3 more
doaj   +2 more sources

Involvement of CX3CL1/CX3CR1 signaling in spinal long term potentiation. [PDF]

open access: yesPLoS ONE, 2015
The long-term potentiation (LTP) of spinal C-fiber-evoked field potentials is considered as a fundamental mechanism of central sensitization in the spinal cord.
Chao Bian   +3 more
doaj   +1 more source

Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity

open access: yesEuropean Journal of Cell Biology, 2023
Dendritic spines form the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Morphological changes of dendritic spines contribute to major forms of synaptic plasticity such as long-term potentiation (LTP) or depression (LTD ...
Anika Heinze, Marco B. Rust
doaj   +1 more source

Long-Term Potentiation and Memory [PDF]

open access: yesPhysiological Reviews, 2004
Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
Lynch, M. A., Ma, Lynch
openaire   +3 more sources

Long-term potentiation in isolated dendritic spines. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:In brain, N-methyl-D-aspartate (NMDA) receptor (NMDAR) activation can induce long-lasting changes in synaptic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor (AMPAR) levels.
Amadou T Corera   +2 more
doaj   +1 more source

Core-Shell Dual-Gate Nanowire Charge-Trap Memory for Synaptic Operations for Neuromorphic Applications

open access: yesNanomaterials, 2021
This work showcases the physical insights of a core-shell dual-gate (CSDG) nanowire transistor as an artificial synaptic device with short/long-term potentiation and long-term depression (LTD) operation.
Md. Hasan Raza Ansari   +2 more
doaj   +1 more source

Purkinje cells translate subjective salience into readiness to act and choice performance

open access: yesCell Reports, 2021
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain.
Lorenzo Bina   +4 more
doaj   +1 more source

Rapid Recovery From Cortical Blindness Caused by an Old Cerebral Infarction

open access: yesFrontiers in Neurology, 2020
When the primary visual cortex (V1) is damaged, cortical blindness results. However, visual information obtained from the superior colliculus (SC) or direct thalamic afferents to higher visual cortices produces unconscious visual functions called ...
Katsuei Shibuki   +5 more
doaj   +1 more source

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