Results 261 to 270 of about 739,569 (400)

The Long non-coding RNA MALAT1 functions as a competing endogenous RNA to regulate vascular remodeling by sponging miR-145-5p/HK2 in hypertension

, 2023
Jiangyong Yang, Guojun Jiang, Ling Huang, Zhongyi Liu, Rengui Jiang, Gang Cao, Jun Cao, Hengqing Zhu, Lemei Chen, Xiaohong Chen, Fang Pei   +10 more
openalex   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development. [PDF]

Commun Biol
Mattiske D, Bernard P, Gradie PE, Behringer RR, Overbeek PA, J O'Neill R, Phillips T, Stewart M, Youngson N, Tarulli G, Pask AJ.   +10 more
europepmc   +1 more source

Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA

Genomics, Proteomics & Bioinformatics, 2017
Iain M. Dykes, C. Emanueli
semanticscholar   +1 more source

SAT-403 Identification of exosomal long non-coding RNAs in patients with IgA nephropathy through high-throughput sequencing analysis

, 2020
Guo Ningru, Qi Zhou, Xue‐kun Huang, Jing Yu, Qingfang Han, Baoting Nong, Yan Xiong, Pan-Hong Liang, J. Li, Min Feng, J. Lv, Y. QIONGQIONG   +11 more
openalex   +1 more source

Long non-coding RNAs in cancer

Non-coding RNA Research, 2019
openaire   +2 more sources

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

The syntenic long non-coding RNA DANCR is an essential regulator of zebrafish development and a human melanoma oncogene. [PDF]

PLoS Genet
Jones SME, Coe EA, Shapiro M, Gallacher KM, Sosa KC, Nikolaou N, Ulitsky I, Kelsh RN, Vance KW.   +8 more
europepmc   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

DRBD3 regulates long non-coding RNA abundance and cryptic splice site selection in trypanosomes. [PDF]

Cell Mol Life Sci
Ceballos-Pérez G, Gómez-Liñán C, Sánchez-Luque FJ, Pérez-Victoria JM, Estévez AM.   +4 more
europepmc   +1 more source