Results 91 to 100 of about 173,449 (258)

Computational identification and analysis of noncoding RNAs - Unearthing the buried treasures in the genome [PDF]

open access: yes, 2007
The central dogma of molecular biology states that the genetic information flows from DNA to RNA to protein. This dogma has exerted a substantial influence on our understanding of the genetic activities in the cells.
Vaidyanathan, P. P., Yoon, Byung-Jun
core  

Divergent lncRNAs take the lead on pluripotent cell differentiation [PDF]

open access: yes, 2016
[No abstract ...
Ballarino, Monica, Rosa, Alessandro
core   +1 more source

The fate of Arabidopsis thaliana homeologous CNSs and their motifs in the Paleohexaploid Brassica rapa. [PDF]

open access: yes, 2013
Following polyploidy, duplicate genes are often deleted, and if they are not, then duplicate regulatory regions are sometimes lost. By what mechanism is this loss and what is the chance that such a loss removes function?
Freeling, Michael   +3 more
core   +2 more sources

Downregulation of a novel long noncoding RNA TRPM2-AS promotes apoptosis in non–small cell lung cancer

open access: yesTumor Biology, 2017
Non–small cell lung cancer is one of the most common types of cancer, and the prognosis of non–small cell lung cancer is still poor. Recent evidence has proved that long noncoding RNA is involved in tumorigenesis.
Cheng Huang   +10 more
doaj   +1 more source

The State of Long Non-Coding RNA Biology

open access: yesNon-Coding RNA, 2018
Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals and other complex organisms is expressed in highly dynamic and cell-specific patterns to produce large numbers of intergenic, antisense and intronic long non ...
John S. Mattick
doaj   +1 more source

The role of noncoding RNAs in metabolic reprogramming of cancer cells

open access: yesCellular & Molecular Biology Letters, 2023
Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread.
Amir Safi   +7 more
doaj   +1 more source

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

open access: yes, 2019
The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored.
Bansal, V.   +13 more
core   +1 more source

Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions. [PDF]

open access: yesPLoS ONE, 2015
CCCTC binding factor (CTCF) is involved in organizing chromosomes into mega base-sized, topologically associated domains (TADs) along with other factors that define sub-TAD organization.
Ifeoma Jane Nwigwe   +3 more
doaj   +1 more source

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context [PDF]

open access: yes, 2018
Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling ...
Abdel-Rahman, Mohamed H.   +736 more
core   +3 more sources

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