Results 101 to 110 of about 111,095 (213)

Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer

, 2023
Liver cancer is the second leading cause of cancer-related death globally, with limited treatment options. Recent studies have demonstrated the critical role of long noncoding RNAs (lncRNAs) in the pathogenesis of liver cancers.
Jiangao Fan, Huiping Zhou, Weidong Chen, Yanyan Wang, Jing Zeng, Phillip B. Hylemon   +5 more
core   +1 more source

Identification and function of long non-coding RNA

Frontiers in Cellular Neuroscience, 2013
Long non-coding (lnc) RNAs are defined as non-protein coding RNAs distinct from housekeeping RNAs such as tRNAs, rRNAs, and snRNAs, and independent from small RNAs with specific molecular processing machinery such as micro- or piwi-RNAs.
Carl eErnst, Cynthia C Morton
doaj   +1 more source

Inhibition of HCV translation by disrupting the structure and interactions of the viral CRE and 3' X-tail [PDF]

, 2015
A phylogenetically conserved RNA structure within the NS5B coding region of hepatitis C virus functions as a cis-replicating element (CRE). Integrity of this CRE, designated SL9266 (alternatively 5BSL3.2), is critical for genome replication. SL9266 forms
Struthers, M, Tuplin, AK, Tuplin, Andrew, Bentley, K, Struthers, Madeleine, Cook, J, Cook, Jonathan, Evans, DJ, Evans, David J., Struthers, Madeline, Bentley, Kirsten, Cook, Jonathan P.   +11 more
core   +1 more source

Noncoding elements in wheat defence response to fusarium head blight

Scientific Reports
Wheat (Triticum aestivum L.) is a major source of global food security while various stressors, including biotic and abiotic factors, directly affect its production.
Tugdem Muslu, Kadriye Kahraman, Bala Ani Akpinar, Halise Busra Cagirici, Egan Jaronski, Cliff Bradley, Hikmet Budak   +6 more
doaj   +1 more source

Noncoder : a web interface for exon array-based detection of long non-coding RNAs

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Uchida, Shizuka, Gellert, Pascal, Ponomareva, Yuliya   +3 more
core   +1 more source

Long non-coding RNA Databases in Cardiovascular Research

Genomics, Proteomics & Bioinformatics, 2016
With the rising interest in the regulatory functions of long non-coding RNAs (lncRNAs) in complex human diseases such as cardiovascular diseases, there is an increasing need in public databases offering comprehensive and integrative data for all aspects ...
Frank Rühle, Monika Stoll
doaj   +1 more source

Chromosome fusions triggered by noncoding RNA

, 2016
Chromosomal fusions are common in normal and cancer cells and can produce aberrant gene products that promote transformation. The mechanisms driving these fusions are poorly understood, but recurrent fusions are widespread.
Bracht, John R, John R. Bracht (277573), Keerthi Shetty (2819902), Nowacki, Mariusz, Derek M. Clay (2819890), Grace J. Uttarotai (2819887), Wang, Xing, Xiao Chen (260187), Chen, Xiao, Sierra S. McCloud (2819899), Wang, Jingmei, Shetty, Keerthi, Laura F. Landweber (19272), Callihan, Evan C, Uttarotai, Grace J, Clay, Derek M, Evan C. Callihan (2819893), Xing Wang (154377), Jingmei Wang (2819896), Landweber, Laura F, Mariusz Nowacki (129438), McCloud, Sierra S   +21 more
core   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
I. M. Jones, Gould, EA, Tuplin, Andrew, Gould, E. A., A. Buckley, E. A. Gould, A. Tuplin, Tuplin, A., Jones, I. M., Jones, I. M. (Ian M.), Buckley, A., Gould, E., T. S. Gritsun, Jones, IM, Gritsun, T. S., Tuplin, A, Evans, DJ, Evans, David J., Gritsun, TS, D. J. Evans, Evans, D. J., Buckley, A   +21 more
core   +1 more source

Upregulation of long noncoding RNA LINC00152 promotes proliferation and metastasis of esophageal squamous cell carcinoma

, 2019
Yi Yang,1,* Xiangwei Sun,2,* Chuang Chi,3 Yu Liu,3 Chaoxi Lin,3 Deyao Xie,3 Xian Shen,2 Xiaoming Lin31Department of Clinical Skills Experiments Center, Wenzhou Medical University, Wenzhou, Zhejiang 325035, People’s Republic of China; 2Department of
Liu Y, Xie D, Yang Y, Lin C, Chi C, Lin X, Sun X, Shen X   +7 more
core  

Long noncoding RNA expression profiling in cancer : challenges and opportunities

, 2019
In recent years, technological advances in transcriptome profiling revealed that the repertoire of human RNA molecules is more diverse and extended than originally thought.
Lorenzi, Lucia, Everaert, Celine, Speleman, Franki, Vandesompele, Jo, Decock, Anneleen, Avila Cobos, Francisco, Lefever, Steve, Verboom, Karen, Helsmoortel, Hetty, Volders, Pieter-Jan, Mestdagh, Pieter   +10 more
core   +1 more source