Results 91 to 100 of about 111,095 (213)
Long noncoding RNA in liver diseases [PDF]
Hepatology, 2014 The identification of the presence of large RNA transcripts that do not code for proteins but that may have biological functions has provided an important new perspective in gene regulation. These long noncoding RNAs (lncRNAs) are being increasingly recognized to contribute to many biological processes through diverse ...
Kenji, Takahashi +3 more
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Cytoplasmic functions of long noncoding RNAs [PDF]
WIREs RNA, 2018 Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found throughout the cell that lack protein‐coding function. Their functions are closely linked to their interaction with RNA‐binding proteins (RBPs) and nucleic acids. Nuclear lncRNAs have been studied extensively, revealing complexes with structural and regulatory roles that ...
Ji Heon, Noh +4 more
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Long noncoding RNAs in cell biology
Seminars in Cell & Developmental Biology, 2011 Whole genome transcriptomic analyses have identified large numbers of dynamically expressed long non-protein-coding RNAs (lncRNAs) in mammals and other animals whose functions are, as yet, largely unknown. Here we summarize the growing evidence that lncRNAs, like mRNAs, can be trafficked to and function in a wide variety of subcellular locations ...
Clark, Michael B., Mattick, John S.
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ZFAS1: a novel tumor-related long non-coding RNA
Cancer Cell International, 2018 Long non-coding RNAs (lncRNA) are classified as a kind of RNA, which are longer than 200 nucleotides in length and cannot be translated into proteins. Multiple studies have demonstrated that lncRNAs are involved in various cellular processes, including ...
Dan Dong +3 more
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, 2016 Wei Liu, Jun Ma, Yong Cheng, Hongbo Zhang, Wengguang Luo, Hongyan Zhang Department of Radiation Oncology, Anhui Provincial Hospital, Hefei, People’s Republic of China Abstract: Recently, accumulating evidence has suggested that long ...
Zhang H, Luo W, Ma J, Cheng Y, Liu W
core
Brazilian Journal of Medical and Biological ResearchIn our study, we aimed to reveal potential long non-coding RNAs (lncRNA) biomarkers in lung adenocarcinoma (LAD) using lncRNA-mediated competing endogenous RNAs (ceRNAs) network (LMCN).
T-G. Zhu +4 more
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, 2020 Introduction The aim of the present study was to investigate the roles of long noncoding RNA (lncRNA) MALAT1 in the development of sepsis-induced acute kidney injury (septic AKI) and the underlying mechanism. Material and methods The levels of MALAT1 in
Haibo Liu, Jinxia Li, Chao Li
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Long noncoding RNAs in biology and hematopoiesis
Blood, 2013 Abstract Genome and transcriptome sequencing have revealed a rich assortment of noncoding RNAs in eukaryote cells, including long noncoding RNAs (lncRNAs), which regulate gene expression independent of protein coding potential. LncRNAs modulate protein coding gene expression in many cell types by regulating multiple processes, including ...
Vikram R, Paralkar, Mitchell J, Weiss
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, 2002 We used an infectious cDNA clone of Porcine reproductive and respiratory syndrome virus (PRRSV) to investigate the presence of essential replication elements in the region of the genome encoding the structural proteins.
R. C. L. Olsthoorn +10 more
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Advances in the role of noncoding RNA in temporomandibular arthritis
Kouqiang hemian waike zazhiTemporomandibular joint osteoarthritis (TMJOA) is a common clinical disease. However, the pathogenesis of TMJOA is still unclear, and there is a lack of effective treatment, bringing great distress to patients.
WU Wenjing, SU Jiansheng
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