Results 101 to 110 of about 162,179 (208)

Computational identification and analysis of noncoding RNAs - Unearthing the buried treasures in the genome [PDF]

, 2007
The central dogma of molecular biology states that the genetic information flows from DNA to RNA to protein. This dogma has exerted a substantial influence on our understanding of the genetic activities in the cells.
Vaidyanathan, P. P., Yoon, Byung-Jun
core  

Smoking affects gene expression in blood of patients with ischemic stroke. [PDF]

, 2019
ObjectiveThough cigarette smoking (CS) is a well-known risk factor for ischemic stroke (IS), there is no data on how CS affects the blood transcriptome in IS patients.MethodsWe recruited IS-current smokers (IS-SM), IS-never smokers (IS-NSM), control ...
Ander, Bradley P, Cheng, Xiyuan, Ferino, Eva, Hull, Heather, Jickling, Glen C, Sharp, Frank R, Stamova, Boryana   +6 more
core   +2 more sources

Advances in the role of noncoding RNA in temporomandibular arthritis

Kouqiang hemian waike zazhi
Temporomandibular joint osteoarthritis (TMJOA) is a common clinical disease. However, the pathogenesis of TMJOA is still unclear, and there is a lack of effective treatment, bringing great distress to patients.
WU Wenjing, SU Jiansheng
doaj   +1 more source

The non-coding RNA landscape of plasma cell dyscrasias [PDF]

, 2020
Despite substantial advancements have been done in the understanding of the pathogenesis of plasma cell (PC) disorders, these malignancies remain hard-to-treat.
Azab, Kareem A, et al,, Morelli, Eugenio, Rocca, Roberta   +3 more
core   +1 more source

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]

, 2019
Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D., Newburn, Laura R., White, K. Andrew   +2 more
core   +1 more source

Identification and function of long non-coding RNA

Frontiers in Cellular Neuroscience, 2013
Long non-coding (lnc) RNAs are defined as non-protein coding RNAs distinct from housekeeping RNAs such as tRNAs, rRNAs, and snRNAs, and independent from small RNAs with specific molecular processing machinery such as micro- or piwi-RNAs.
Carl eErnst, Cynthia C Morton
doaj   +1 more source

Noncoding elements in wheat defence response to fusarium head blight

Scientific Reports
Wheat (Triticum aestivum L.) is a major source of global food security while various stressors, including biotic and abiotic factors, directly affect its production.
Tugdem Muslu, Kadriye Kahraman, Bala Ani Akpinar, Halise Busra Cagirici, Egan Jaronski, Cliff Bradley, Hikmet Budak   +6 more
doaj   +1 more source

Distributions of Triplets in Genetic Sequences [PDF]

, 1997
Distributions of triplets in some genetic sequences are examined and found to be well described by a 2-parameter Markov process with a sparse transition matrix.
Boon, David Kessler, Ido Kanter, Kanter, Li, Mandelbrot, Perline, Schenkel, Shi, Shtrikman, Yu Shi   +10 more
core   +3 more sources

Long non-coding RNA Databases in Cardiovascular Research

Genomics, Proteomics & Bioinformatics, 2016
With the rising interest in the regulatory functions of long non-coding RNAs (lncRNAs) in complex human diseases such as cardiovascular diseases, there is an increasing need in public databases offering comprehensive and integrative data for all aspects ...
Frank Rühle, Monika Stoll
doaj   +1 more source

A new cancer/testis long noncoding RNA, the OTP-AS1 RNA

Scientific Reports
The orthopedia homeobox (OTP) gene encodes a homeodomain-containing transcription factor involved in brain development. OTP is mapped to human chromosome 5q14.1.
Iuliia K. Karnaukhova, Dmitrii E. Polev, Larisa L. Krukovskaya, Andrei A. Makashov, Alexey E. Masharsky, Olga V. Nazarenko, Irina V. Poverennaya, Vsevolod J. Makeev, Ekaterina B. Akulova, Andrei P. Kozlov   +9 more
doaj   +1 more source