Results 11 to 20 of about 7,356,485 (255)

Long Noncoding RNAs in Metabolic Syndrome Related Disorders [PDF]

Mediators of Inflammation, 2016
Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (
Magdalena Losko, Jerzy Kotlinowski, Jolanta Jura   +2 more
doaj   +2 more sources

Functional insights into long antisense noncoding RNA Kcnq1ot1 mediated bidirectional silencing

, 2008
The prevailing view has been that noncoding antisense RNA primarily regulates the transcriptional activity of its sense counterpart, however, a subset of long noncoding antisense RNAs, such as Kcnq1ot1 and Air, have been shown to regulate the ...
Kanduri, Chandrasekhar,
core   +7 more sources

애기 장대에서 잎의 노화 관련 long noncoding RNA (lncRNA)의 조절 역할의 글로벌 분석

, 2021
식물,노화,애기장대,전사체,Long noncoding RNA,lncRNA,leaf senescence,Arabidopsis, senescence-associated long noncoding RNA ...
Jungyeon Kim
core   +1 more source

KCNQ1OT1: An Oncogenic Long Noncoding RNA

Biomolecules, 2021
Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle, Qi Qi, Suryakant Niture, Deepak Kumar   +3 more
doaj   +1 more source

Long Noncoding RNA Plasmacytoma Variant Translocation 1 Is Increased in Multiple Myeloma and Correlates With Lower Induction Response

Technology in Cancer Research & Treatment, 2020
Objective: This study aimed to investigate the correlation of long noncoding RNA plasmacytoma variant translocation 1 with clinical features and prognosis in patients with multiple myeloma.
Pei Li MD, Xiyao Han MD, Yinghua Xie MM, Yihan Liu MD   +3 more
doaj   +1 more source

Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome [PDF]

, 2015
This work was supported by the Biotechnology and Biological Sciences Research Council and The Wellcome Trust. A.N. was supported by the Swiss National Science Foundation (Grant: PZ00P3_142636). H.K. was supported by the European Research Council Starting
Ness, Rob W, Keightley, Peter D, Kaessmann, H., Keightley, P. D., Halligan, D. L., Ness, R. W., Wiberg, R.A., Wiberg, Ralf Axel Wilhelm, Halligan, Daniel L, Ness, R.W., Keightley, P.D., Keightley, Peter D., Kaessmann, Henrik, Wiberg, R. A., Wiberg, R Axel W, Ness, Rob W., Necsulea, A., Halligan, D.L., Halligan, Daniel L., Necsulea, Anamaria, Wiberg, R. Axel W., Ness RW, Keightley PD, Wiberg RA, Necsulea A, Kaessmann H, Halligan DL   +26 more
core   +2 more sources

LINC00467: an oncogenic long noncoding RNA

Cancer Cell International, 2022
Long non-coding RNAs (lncRNAs) have been found to play essential roles in the cell proliferation, fission and differentiation, involving various processes in humans.
Xuyu Chen, Qian Luo, Yanan Xiao, Jing Zhu, Yirao Zhang, Jie Ding, Juan Li   +6 more
doaj   +1 more source

Flnc: Machine Learning Improves the Identification of Novel Long Noncoding RNAs from Stand-Alone RNA-Seq Data

, 2022
Long noncoding RNAs (lncRNAs) play critical regulatory roles in human development and disease. Although there are over 100,000 samples with available RNA sequencing (RNA-seq) data, many lncRNAs have yet to be annotated.
Kwon, Euijin, Zhou, Chan, Li, Zixiu, Fitzgerald, Katherine A, Zhou, Peng, Weng, Zhiping   +5 more
core   +1 more source

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15 [PDF]

, 2023
Summary: The noncoding genome presents a largely untapped source of new biological insights, including thousands of long noncoding RNA (lncRNA) loci. While lncRNA dysregulation has been reported in myeloid malignancies, their functional relevance remains
Michelle Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Michael Heuser, Dorit Borchert, Dirk Heckl, Robert Winkler, Jan-Henning Klusmann, Marit Willemijn Vermunt, Leah Schüler, Marie-Laure Yaspo, Konstantin Schuschel, Eniko Regenyi, Dirk Reinhardt, Oriol Alejo   +15 more
core   +4 more sources

Role of Related Regulatory Long Noncoding RNAs on Mammalian Spermatogenesis

Reproductive and Developmental Medicine, 2017
Long noncoding RNAs (lncRNAs) are transcribed by RNA molecules, which are longer than 200 nucleotides that lack an open reading frame of significant length and possess no obvious protein-coding capacity.
Kang-Sheng Liu, Xiao-Dong Mao, Feng Pan, Ling-Juan Gao, Xiu-Feng Ling   +4 more
doaj   +1 more source