Results 21 to 30 of about 7,356,485 (255)

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B [PDF]

, 2008
The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5' and 3' non-coding regions (NCR), and in the NS5B coding sequence.
Diviney, Sinéad, Elliot, R., Evans, David John, Evans, D., Armstrong, V, Tuplin, Andrew, Evans, D.J., Struthers, Madeleine, Struthers, M., Elliott, Richard M., Diviney, S., Tuplin, A., Armstrong, V., Struthers, M, Simmonds, Peter, Elliott, Richard Michael, Armstrong, Victoria, Tuplin, A, Evans, David J., Simmonds, P., Diviney, S, Elliott, R.M., Simmonds, P, Evans, David John; id_orcid   +23 more
core   +1 more source

Human cancer long non-coding RNA transcriptomes. [PDF]

PLoS ONE, 2011
Once thought to be a part of the 'dark matter' of the genome, long non-coding RNAs (lncRNAs) are emerging as an integral functional component of the mammalian transcriptome.
Ewan A Gibb, Emily A Vucic, Katey S S Enfield, Greg L Stewart, Kim M Lonergan, Jennifer Y Kennett, Daiana D Becker-Santos, Calum E MacAulay, Stephen Lam, Carolyn J Brown, Wan L Lam   +10 more
doaj   +1 more source

The Regulatory Activity of Noncoding RNAs in ILCs

Cells, 2021
Innate lymphoid cells (ILCs) are innate lymphocytes playing essential functions in protection against microbial infections and participate in both homeostatic and pathological contexts, including tissue remodeling, cancer, and inflammatory disorders.
Alessio Grimaldi, Giuseppe Pietropaolo, Helena Stabile, Andrea Kosta, Cristina Capuano, Angela Gismondi, Angela Santoni, Giuseppe Sciumè, Cinzia Fionda   +8 more
doaj   +1 more source

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]

, 2013
: OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E., Callaghan, Anastasia J., Helen A. Vincent, Phillips, Jack O., Cary, Peter, Vincent, H., Peter D. Cary, Sobott, F., Jack O. Phillips, Frank Sobott, Vincent, Helen A., Henderson, Charlotte A., Stone, Carlanne, Alessandra Casamento, Henderson, Charlotte, Carlanne M. Stone, Anastasia J. Callaghan, Darren M. Gowers, Cary, Peter D., Charlotte A. Henderson, James E.N. Taylor, Casamento, A., Callaghan, Anastasia, Phillips, Jack, Gowers, Darren, Casamento, Alessandra, Stone, Carlanne M., Sobott, Frank, Gowers, Darren M.   +28 more
core   +1 more source

Assessment of the Cardiac Noncoding Transcriptome by Single-Cell RNA Sequencing Identifies FIXER, a Conserved Profibrogenic Long Noncoding RNA. [PDF]

, 2023
BACKGROUND Cardiac fibroblasts have crucial roles in the heart. In particular, fibroblasts differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation and interstitial fibrosis.
Bernasconi, R., Wigger, Leonore, Plaisance, Isabelle, Alexandre Sarre, Leonore Wigger, Pedrazzini, Thierry, Plaisance, I., Sarre, A., Wyss, Tania, Wyss, T., Panagiotis Chouvardas, Arantxa González, Pulido Quetglas, C., Aghagolzadeh, Parisa, Mohamed Nemir, Nemir, Mohamed, Bernasconi, Riccardo, Tania Wyss, Sarre, Alexandre, Wigger, L., Treibel, Thomas A, Riccardo Bernasconi, Pedrazzini, T., Thierry Pedrazzini, Nemir, M., González, Arantxa, Rory Johnson, Johnson, R., Pulido Quetglas, Carlos, Isabelle Plaisance, Chouvardas, P., Chouvardas, Panagiotis, Johnson, Rory, Thomas A. Treibel, Aghagolzadeh, P., Carlos Pulido Quetglas, Parisa Aghagolzadeh, González, A., Treibel, T.A.   +38 more
core   +1 more source

Integrated Profiling Revealed Potential Regulatory Networks Among Long Noncoding RNAs and mRNAs in Mucosal Gastric Cancer

Technology in Cancer Research & Treatment, 2020
Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient ...
Ke-kang Sun MD, Xiao-jun Shen MM, Dong Yang MM, Yang Jiao PhD, Xiao-yang Wu PhD   +4 more
doaj   +1 more source

Transcriptional network modulated by the prognostic signature transcription factors and their long noncoding RNA partners in primary prostate cancer

EBioMedicine, 2021
Background: Transcriptional regulators are seminal players in the onset and progression of prostate cancer. However, clarification of their underlying regulatory circuits and mechanisms demands considerable effort.
Mei Jiang, Yihang Cheng, Dan Wang, Yali Lu, Shaohua Gu, Chenji Wang, Yan Huang, Yao Li   +7 more
doaj   +1 more source

Review: Long non-coding RNA in livestock

Animal, 2020
Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi, M. Mielczarek, J. Szyda   +2 more
doaj   +1 more source

Long non-coding RNA and diseases [PDF]

Jichu yixue yu linchuang
Long non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.

doaj   +1 more source

MALAT1 Long Non-Coding RNA: Functional Implications

Non-Coding RNA, 2020
The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Gayatri Arun, Disha Aggarwal, David L. Spector   +2 more
doaj   +1 more source