Results 31 to 40 of about 111,095 (213)

Panning for Long Noncoding RNAs [PDF]

Biomolecules, 2013
The recent advent of high-throughput approaches has revealed widespread transcription of the human genome, leading to a new appreciation of transcription regulation, especially from noncoding regions. Distinct from most coding and small noncoding RNAs, long noncoding RNAs (lncRNAs) are generally expressed at low levels, are less conserved and lack ...
Li Yang, Xiao-Ou Zhang, Shanshan Zhu
openaire   +3 more sources

Long Noncoding RNA Plasmacytoma Variant Translocation 1 Is Increased in Multiple Myeloma and Correlates With Lower Induction Response

Technology in Cancer Research & Treatment, 2020
Objective: This study aimed to investigate the correlation of long noncoding RNA plasmacytoma variant translocation 1 with clinical features and prognosis in patients with multiple myeloma.
Pei Li MD, Xiyao Han MD, Yinghua Xie MM, Yihan Liu MD   +3 more
doaj   +1 more source

LINC00467: an oncogenic long noncoding RNA

Cancer Cell International, 2022
Long non-coding RNAs (lncRNAs) have been found to play essential roles in the cell proliferation, fission and differentiation, involving various processes in humans.
Xuyu Chen, Qian Luo, Yanan Xiao, Jing Zhu, Yirao Zhang, Jie Ding, Juan Li   +6 more
doaj   +1 more source

Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome [PDF]

, 2015
This work was supported by the Biotechnology and Biological Sciences Research Council and The Wellcome Trust. A.N. was supported by the Swiss National Science Foundation (Grant: PZ00P3_142636). H.K. was supported by the European Research Council Starting
Ness, Rob W, Keightley, Peter D, Kaessmann, H., Keightley, P. D., Halligan, D. L., Ness, R. W., Wiberg, R.A., Wiberg, Ralf Axel Wilhelm, Halligan, Daniel L, Ness, R.W., Keightley, P.D., Keightley, Peter D., Kaessmann, Henrik, Wiberg, R. A., Wiberg, R Axel W, Ness, Rob W., Necsulea, A., Halligan, D.L., Halligan, Daniel L., Necsulea, Anamaria   +19 more
core   +1 more source

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B [PDF]

, 2008
The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5' and 3' non-coding regions (NCR), and in the NS5B coding sequence.
Diviney, Sinéad, Elliot, R., Evans, David John, Evans, D., Armstrong, V, Tuplin, Andrew, Evans, D.J., Struthers, Madeleine, Struthers, M., Elliott, Richard M., Diviney, S., Tuplin, A., Armstrong, V., Struthers, M, Simmonds, Peter, Elliott, Richard Michael, Armstrong, Victoria, Tuplin, A, Evans, David J., Simmonds, P., Diviney, S, Elliott, R.M., Simmonds, P   +22 more
core   +1 more source

Long noncoding RNAs and neuroblastoma

Oncotarget, 2015
Neuroblastoma is a disease that affects infants and despite intense multimodal therapy, high-risk patients have low survival rates (
Gaurav Kumar, Pandey, Chandrasekhar, Kanduri   +1 more
openaire   +3 more sources

Long Noncoding RNAs in Atherosclerosis

Journal of Atherosclerosis and Thrombosis, 2016
Long noncoding RNAs (lncRNAs) were a group of non-protein-coding RNAs ＞200 nucleotides and participated in biological processes and pathophysiological conditions in vivo or in vitro. Recently, more and more lncRNAs interfering with the progress of atherosclerosis were identified and characterized in the atherogenic cells such as vascular smooth muscle ...
Jian, Liguo, Jian, Dongdong, Chen, Qishan, Zhang, Li   +3 more
openaire   +3 more sources

Role of Related Regulatory Long Noncoding RNAs on Mammalian Spermatogenesis

Reproductive and Developmental Medicine, 2017
Long noncoding RNAs (lncRNAs) are transcribed by RNA molecules, which are longer than 200 nucleotides that lack an open reading frame of significant length and possess no obvious protein-coding capacity.
Kang-Sheng Liu, Xiao-Dong Mao, Feng Pan, Ling-Juan Gao, Xiu-Feng Ling   +4 more
doaj   +1 more source

The Regulatory Activity of Noncoding RNAs in ILCs

Cells, 2021
Innate lymphoid cells (ILCs) are innate lymphocytes playing essential functions in protection against microbial infections and participate in both homeostatic and pathological contexts, including tissue remodeling, cancer, and inflammatory disorders.
Alessio Grimaldi, Giuseppe Pietropaolo, Helena Stabile, Andrea Kosta, Cristina Capuano, Angela Gismondi, Angela Santoni, Giuseppe Sciumè, Cinzia Fionda   +8 more
doaj   +1 more source

Human cancer long non-coding RNA transcriptomes. [PDF]

PLoS ONE, 2011
Once thought to be a part of the 'dark matter' of the genome, long non-coding RNAs (lncRNAs) are emerging as an integral functional component of the mammalian transcriptome.
Ewan A Gibb, Emily A Vucic, Katey S S Enfield, Greg L Stewart, Kim M Lonergan, Jennifer Y Kennett, Daiana D Becker-Santos, Calum E MacAulay, Stephen Lam, Carolyn J Brown, Wan L Lam   +10 more
doaj   +1 more source