Results 61 to 70 of about 173,449 (258)

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. [PDF]

, 2016
Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across multiple tumour types. However, to date, cancer profiling has largely focused on protein-coding genes, which
Backofen, Rolf, Cao, Xuhong, Chinnaiyan, Arul M, Collins, Colin, Feng, Felix Y, Gawronski, Alexander, Han, Sumin, Hayes, Daniel F, Hosono, Yasuyuki, Iyer, Matthew K, Kregel, Steven, Ma, Teng, Malik, Rohit, Niknafs, Yashar S, Pierce, Lori J, Pitchiaya, Sethuramasundaram, Poliakov, Anton, Prensner, John R, Rae, James M, Sahinalp, Cenk S, Siebenaler, Ronald F, Singhal, Udit, Speers, Corey, Uhl, Michael, Wilder-Romans, Kari, Xiao, Lanbo, Zhang, Chao, Zhao, Shuang G   +27 more
core   +1 more source

Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia [PDF]

, 2015
Long non-coding RNAs (lncRNAs) are important regulators of gene expression that influence almost every step in the life cycle of genes, from transcription to mRNA splicing, RNA decay, and translation.
Ballarino, Monica, Fatica, Alessandro, Morlando, Mariangela   +2 more
core   +2 more sources

Long Noncoding RNA Regulation of Pluripotency

Stem Cells International, 2016
Pluripotent stem cells (PSCs) represent a unique kind of stem cell, as they are able to indefinitely self-renew and hold the potential to differentiate into any derivative of the three germ layers.
Alessandro Rosa, Monica Ballarino
doaj   +1 more source

ALDB: a domestic-animal long noncoding RNA database. [PDF]

PLoS ONE, 2015
Long noncoding RNAs (lncRNAs) have attracted significant attention in recent years due to their important roles in many biological processes. Domestic animals constitute a unique resource for understanding the genetic basis of phenotypic variation and ...
Aimin Li, Junying Zhang, Zhongyin Zhou, Lei Wang, Yujuan Liu, Yajun Liu   +5 more
doaj   +1 more source

Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum. [PDF]

, 2015
BackgroundPlasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging.
Bunnik, Evelien M, Le Roch, Karine G, Lonardi, Stefano, Lu, Xueqing Maggie, Nasseri, Sara, Pokhriyal, Neeti   +5 more
core   +2 more sources

LncRNA-GAS5 Inhibits Expression of miR 103 and Ameliorates the Articular Cartilage in Adjuvant-Induced Arthritis in Obese Mice

Dose-Response, 2020
We explored whether long noncoding RNA growth arrest-specific transcript 5 (LncRNA-GAS5) small interfering RNA (siRNA) reduced cartilage destruction in obese mice with adjuvant-induced arthritis.
Hongwei Chen, Chuan He, Yan Liu, Xiaolin Li, Chaoju Zhang, Qunyan Qin, Qixiong Pang   +6 more
doaj   +1 more source

Research Progress on Plant Long Non-Coding RNA

Plants, 2020
Non-coding RNAs (ncRNAs) that were once considered “dark matter” or “transcriptional noise” in genomes are research hotspots in the field of epigenetics.
Ling Wu, Sian Liu, Haoran Qi, Heng Cai, Meng Xu   +4 more
doaj   +1 more source

Long noncoding RNA in liver diseases [PDF]

Hepatology, 2014
The identification of the presence of large RNA transcripts that do not code for proteins but that may have biological functions has provided an important new perspective in gene regulation. These long noncoding RNAs (lncRNAs) are being increasingly recognized to contribute to many biological processes through diverse ...
Kenji, Takahashi, Irene, Yan, Hiroaki, Haga, Tushar, Patel   +3 more
openaire   +2 more sources

Long Non-Coding RNA MEG3 in Metal Carcinogenesis

Toxics, 2023
Most transcripts from human genomes are non-coding RNAs (ncRNAs) that are not translated into proteins. ncRNAs are divided into long (lncRNAs) and small non-coding RNAs (sncRNAs).
Zhuo Zhang, Sophia Shi, Jingxia Li, Max Costa   +3 more
doaj   +1 more source

Retracted: Functional Analysis of Serum Long Noncoding RNAs in Patients with Atrial Fibrillation [PDF]

, 2023
Disease Markers
openalex   +1 more source