Results 61 to 70 of about 111,095 (213)

LncATLAS database for subcellular localization of long noncoding RNAs [PDF]

, 2017
The subcellular localization of long noncoding RNAs (lncRNAs) holds valuable clues to their molecular function. However, measuring localization of newly discovered lncRNAs involves time-consuming and costly experimental methods.
Carlevaro Fita, Joana, Palumbo, Emilio, Hermoso Pulido, Toni, Emilio Palumbo, Rory Johnson, Hermoso Pulido, Antonio, Joana Carlevaro-Fita, Guigó Serra, Roderic, Mas Ponte, David, Carlevaro-Fita, Joana, Mas-Ponte, David, Johnson, Rory, David Mas-Ponte, Roderic Guigo, Guigo, Roderic, Toni Hermoso Pulido   +15 more
core   +1 more source

Long Noncoding RNA Regulation of Pluripotency

Stem Cells International, 2016
Pluripotent stem cells (PSCs) represent a unique kind of stem cell, as they are able to indefinitely self-renew and hold the potential to differentiate into any derivative of the three germ layers.
Alessandro Rosa, Monica Ballarino
doaj   +1 more source

Long Noncoding RNAs in Cardiovascular Disease

Current Opinion in Cardiology, 2019
Purpose of review Here, we review recent findings on the role of long noncoding RNAs (lncRNAs) in cardiovascular disease (CVD). In addition, we highlight some of the latest findings in lncRNA biology, providing an outlook for future avenues of lncRNA research in CVD. Recent findings
Kohlmaier, Alexander, Holdt, Lesca M., Teupser, Daniel   +2 more
openaire   +2 more sources

Long Noncoding RNAs in Cancer Pathways [PDF]

Cancer Cell, 2016
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional mutations within the noncoding genome, with profound effects on the expression of long noncoding RNAs (lncRNAs). While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, we now understand that lncRNAs drive many ...
Adam M, Schmitt, Howard Y, Chang
openaire   +2 more sources

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15 [PDF]

, 2023
The noncoding genome presents a largely untapped source of new biological insights, including thousands of long noncoding RNA (lncRNA) loci. While lncRNA dysregulation has been reported in myeloid malignancies, their functional relevance remains to be ...
Klusmann, J., Reinhardt, D., Winkler, R., Vermunt, M., Borchert, D., Heuser, M., Yaspo, M. ; https://orcid.org/, Bhayadia, R., Alejo, O., Regenyi, E., Ng, M., Schuschel, K., Issa, H., Schüler, L., Heckl, D., Verboon, L.   +15 more
core   +2 more sources

Prognostic value and clinical significance of long noncoding RNA CASC2 in human malignancies: a meta-analysis

, 2018
Juan Cai,1,* Xueliang Zuo,2,* Zhiqiang Chen,3,4,* Wenying Zhao,1 Yiping Zhu,1 Zhengxiang Zhang,1 Xiaobing Ye1 1Department of Oncology, The First Affiliated Hospital, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, China; 2Department of ...
Zhu Y, Zuo X, Cai J, Zhao W, Wenying Zhao, Ye X, Zhiqiang Chen, Juan Cai, Zhengxiang Zhang, Chen Z, Zhang Z, Yiping Zhu, Xiaobing Ye, Xueliang Zuo   +13 more
core   +1 more source

Roles of long noncoding RNA in triple‐negative breast cancer

, 2023
Introduction Long noncoding RNAs (lncRNAs) play crucial roles in regulating various hallmarks in cancers. Triple‐negative (Estrogen receptor, ER; Human epidermal growth factor receptor 2, HER2; Progesterone receptor, PR) breast cancer (TNBC) is the most ...
Soha, Kazi, Pillai, Suja, Das, Plabon Kumar, Siddika, Ayesha, Farhadul Islam, Khan Mohammad Rashel, Rashel, Khan Mohammad, Suja Pillai, Plabon Kumar Das, Abdul Auwal, Rahman, Md Arifur, Ayesha Siddika, Auwal, Abdul, Islam, Farhadul, Kazi Soha, Md. Arifur Rahman   +15 more
core   +1 more source

Long noncoding RNAs in cardiometabolic disorders

FEBS Letters, 2022
The advancement of medical technology has led not only to an increase in life expectancy but also to a rise in aging‐related diseases. Aging promotes metabolic disorders, in turn affecting cardiovascular health. Derailment of biological processes in the pancreas, liver, adipose tissue, and skeletal muscle impairs glucose and lipid metabolism, and ...
Rio P. Juni, Kelly C. 't Hart, Riekelt H. Houtkooper, Reinier A. Boon   +3 more
openaire   +3 more sources

Noncoding RNAs Associated with Therapeutic Resistance in Pancreatic Cancer

Biomedicines, 2021
Therapeutic resistance is an inevitable impediment towards effective cancer therapies. Evidence accumulated has shown that the signaling pathways and related factors are fundamentally responsible for therapeutic resistance via regulating diverse cellular
Seung Wan Son, Mun Gyu Song, Ba Da Yun, Jong Kook Park   +3 more
doaj   +1 more source

ALDB: a domestic-animal long noncoding RNA database. [PDF]

PLoS ONE, 2015
Long noncoding RNAs (lncRNAs) have attracted significant attention in recent years due to their important roles in many biological processes. Domestic animals constitute a unique resource for understanding the genetic basis of phenotypic variation and ...
Aimin Li, Junying Zhang, Zhongyin Zhou, Lei Wang, Yujuan Liu, Yajun Liu   +5 more
doaj   +1 more source