Results 91 to 100 of about 6,745,034 (280)

Short-reads and long-reads require different annotation strategies.

open access: yes, 2015
Reads of various length (70–3,000 bp) were simulated with 1% error rate from mock community 160319967-stool1. (A) Predicted open reading frames (ORFs) were derived either via naïve 6-frame translation (6FT) or via the metagenomic gene finder Prodigal ...
Jonathan A. Eisen (93505)   +7 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

antimicrobial-peptide-cluster-reads

open access: yes, 2013
The raw reads that mapped to each sequence cluster given in antimicrobial-peptide-clusters.fasta.
Robert Scott Cornman (419049)   +3 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Mapping-based genome size estimation

open access: yesBMC Genomics
While the size of chromosomes can be measured under a microscope, obtaining the exact size of a genome remains a challenge. Biochemical methods and k-mer distribution-based approaches allow only estimations. An alternative approach to estimate the genome
Shakunthala Natarajan   +2 more
doaj   +1 more source

Genome sequence of a European Diplocarpon coronariae strain and in silico structure of the mating-type locus

open access: yesFrontiers in Plant Science
Diplocarpon coronariae is a fungal pathogen that is prevalent in low-input apple production. Over the past 15 years, it has become increasingly distributed in Europe. However, comprehensive insights into its biology and pathogenicity remain limited.
Sophie Richter   +13 more
doaj   +1 more source

Transcriptome assembly from long-read RNA-seq alignments with StringTie2

open access: yesGenome Biology, 2019
RNA sequencing using the latest single-molecule sequencing instruments produces reads that are thousands of nucleotides long. The ability to assemble these long reads can greatly improve the sensitivity of long-read analyses.
Sam Kovaka   +5 more
doaj   +1 more source

hAssembler: A hybrid de novo genome assembly approach for large genomes

open access: yesThe Indian Journal of Agricultural Sciences, 2020
Genome assembly is a process where large contigs and scaffolds are constructed from raw reads generated by sequencing machines. Based on the size of the generated reads they can be primarily categorized into short reads and long reads.
AMIT KAIRI   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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