Results 81 to 90 of about 6,745,034 (280)

Scaffolding of long read assemblies using long range contact information

open access: yesBMC Genomics, 2017
Background Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies.
Jay Ghurye   +4 more
doaj   +1 more source

ParMap, an Algorithm for the Identification of Complex Genomic Variations in Nextgen Sequencing Data [PDF]

open access: yes, 2010
Next-generation sequencing produces high-throughput data, albeit with greater error and shorter reads than traditional Sanger sequencing methods. This complicates the detection of genomic variations, especially, small insertions and deletions.
Raul Rabadan   +4 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Other title: Kansas Reads to Preschoolers Program

open access: yes, 2007
application/pdf; On the toolkits: "Compiled by the Kansas Center for the Book and the Kansas Reads to Preschoolers Committee."; Includes bibliographical references.A set of 5 documents provided by the Kansas Center for the Book and the Kansas State ...
Kansas Center for the Book.
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

p300 ChIP-seq peaks using uni- and multi-reads

open access: yes, 2019
ChIP-seq peaks detected following the standard ChIP-seq data processing pipeline of ENCODE (The ENCODE Project Consortium, 2012) using both uni-reads and multi-reads aligned by Permseq (Zeng et al., 2015) for ...
Ye Zheng (169955)   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

ELECTOR: evaluator for long reads correction methods [PDF]

open access: yesNAR Genomics and Bioinformatics, 2019
Abstract The error rates of third-generation sequencing data have been capped >5%, mainly containing insertions and deletions. Thereby, an increasing number of diverse long reads correction methods have been proposed. The quality of the correction has huge impacts on downstream processes.
Marchet, Camille   +6 more
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Kansas Reads to Preschoolers Committee member information. [2020?]

open access: yes, 2020
Information on the Kansas Reads to Preschoolers program for members of the Kansas Reads to Preschoolers ...
Kansas Center for the Book.
core  

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