Results 61 to 70 of about 6,745,034 (280)

Towards Reading Comprehension for Long Documents [PDF]

open access: yesProceedings of the Twenty-Seventh International Joint Conference on Artificial Intelligence, 2018
Machine reading comprehension has gained attention from both industry and academia. It is a very challenging task that involves various domains such as language comprehension, knowledge inference, summarization, etc. Previous studies mainly focus on reading comprehension on short paragraphs, and these approaches fail to perform well on the documents ...
Yuanxing Zhang   +3 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

LRScaf: improving draft genomes using long noisy reads

open access: yesBMC Genomics, 2019
Background The advent of third-generation sequencing (TGS) technologies opens the door to improve genome assembly. Long reads are promising for enhancing the quality of fragmented draft assemblies constructed from next-generation sequencing (NGS ...
Mao Qin   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

VeChat: correcting errors in long reads using variation graphs

open access: yesNature Communications, 2022
Consensus sequence-based methods for self-correction of long-read sequencing data are affected by biases that can mask true variants characterizing little-covered or low-frequency haplotypes.
Xiao Luo   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

More Informative Principal Components For Long Reads.

open access: yes, 2012
First three PCs for the two long reads datasets: real long reads, simulated long reads. At the bottom of each component we reported the cumulative variation represented.
Francesco Vezzi (107361)   +2 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Haplotype and Repeat Separation in Long Reads [PDF]

open access: yes, 2017
Abstract Resolving the correct structure and succession of highly similar sequence stretches is one of the main open problems in genome assembly. For non haploid genomes this includes determining the sequences of the different haplotypes. For all but the smallest genomes it also involves separating different repeat instances.
openaire   +2 more sources

Polishing long reads

open access: yes, 2022
I've been away from this lab notebook for a little while – for good reasons. Pace of projects I'm involved in moved at breakneck speeds, and some of them being publication facing projects ended up enforcing a bit of self-imposed embargo for the stuff I'd normally write about.
openaire   +1 more source

Home - About - Disclaimer - Privacy