Results 91 to 100 of about 46,383 (210)

Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: A multicentre retrospective matched cohort study [PDF]

, 2003
Objectives. To investigate the possible benefits and adverse effects of the addition of lopinavir/ritonavir to a standard treatment protocol for the treatment of severe acute respiratory syndrome. Design. Retrospective matched cohort study. Setting. Four
Chan, KS, Chu, CM, Lai, ST, Peiris, JSM, Que, TL, Sung, J, Tam, CY, Tse, MW, Tsui, E, Wong, MML, Wong, VCW, Yuen, KY   +11 more
core  

Lipometabolic side-effects of three ritonavir-boosted double protease inhibitor regimens without reverse transcriptase inhibitors [PDF]

, 2008
Poster presentation: Purpose of the study To compare the lipometabolic profiles of three double-boosted protease inhibitor (PI) regimens at standard dose, containing saquinavir and ritonavir in combination with lopinavir (LOPSAQ), atazanavir (ATSAQ) or ...
Bickel, Markus, Hentig, Nils von, Khaykin, Pavel, Knecht, Gaby, Lennemann, Tessa, Lutz, Thomas, Staszewski, Schlomo, Stephan, Christoph, Wendig, Annette   +8 more
core   +1 more source

Pediatric human immunodeficiency virus infection in the modern era: A systematic review of recent advances and their implications

Pediatric Investigation, Volume 9, Issue 4, Page 394-404, December 2025.
This review discusses how early antiretroviral therapy initiation, long‐acting therapies, and prevention of mother‐to‐child transmission contribute to improved pediatric human immunodeficiency virus outcomes. Despite these advances, treatment complications and challenges in transitioning to adult care remain major barriers to lifelong management ...
Klaudia Nowak, Krzysztof Łupina, Dominika Lorek, Aleksandra Jabłońska, Alicja Radomska, Tymon Choromański, Jakub Janczura   +6 more
wiley   +1 more source

Intervenciones farmacológicas para el tratamiento de la Enfermedad por Coronavirus (COVID-19)

Anales de la Facultad de Medicina, 2020
Varios fármacos han sido propuestos como alternativas terapéuticas para COVID-19. Se efectuó una búsqueda sistematica en MEDLINE (vía PubMed) hasta el 20 de marzo de 2020, con el fin de identificar la evidencia disponible sobre intervenciones ...
Fabiola Huaroto, Nora Reyes, Karen Huamán, Catherine Bonilla, Maricela Curisinche-Rojas, Gloria Carmona, Ericson Gutierrez, Patricia Caballero   +7 more
doaj   +1 more source

Electrospun Amorphous Solid Dispersions with Lopinavir and Ritonavir for Improved Solubility and Dissolution Rate

Nanomaterials
Lopinavir (LPV) and ritonavir (RTV) are two of the essential antiretroviral active pharmaceutical ingredients (APIs) characterized by poor solubility. Hence, attempts have been made to improve both their solubility and dissolution rate.
Ewelina Łyszczarz, Oskar Sosna, Justyna Srebro, Aleksandra Rezka, Dorota Majda, Aleksander Mendyk   +5 more
doaj   +1 more source

Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration [PDF]

, 2011
Article approval pendingWith expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic failure and switching in
Boulle, Andrew, Davies, Mary-Ann, Egger, Matthias, Eley, Brian, Giddy, Janet, Keiser, Olivia, Moultrie, Harry, Rabie, Helena, Technau, Karl, Van Cutsem, Gilles, Wood, Robin   +10 more
core   +2 more sources

Concomitant contraceptive implant and efavirenz use in women living with HIV: perspectives on current evidence and policy implications for family planning and HIV treatment guidelines. [PDF]

, 2017
IntroductionPreventing unintended pregnancies is important among all women, including those living with HIV. Increasing numbers of women, including HIV-positive women, choose progestin-containing subdermal implants, which are one of the most effective ...
Cohen, Craig R, Kiarie, James, Morroni, Chelsea, Patel, Rena C, Scarsi, Kimberly K, Sripipatana, Tabitha   +5 more
core   +2 more sources

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection [PDF]

, 2003
Although the pathogenesis of human immunodeficiency virus (HIV) infection and the general virologic and immunologic principles underlying the use of antiretroviral therapy are similar for all HIV-infected persons, there are unique considerations needed ...
Antiretroviral Therapy and Medical Management of HIV-Infected Children, ATMMHC, Health Resources and Services Administration, HRSA, National Institutes of Health, NIH, National Pediatric and Family HIV Resource Center, NPHRC   +3 more
core  

ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]

, 2014
BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang, extended ING116070 study team, Letendre, Scott L, Mills, Anthony M, Min, Sherene S, Piscitelli, Stephen C, Song, Ivy H, Tashima, Karen T, Thomas, Deborah A   +8 more
core   +3 more sources

A novel FRET-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters [PDF]

, 2016
The glucose transporter PfHT is essential to the survival of the malaria parasite Plasmodium falciparum and has been shown to be a druggable target with high potential for pharmacological intervention.
Autry, Joseph M, Edwards, Rachel L, Heitmeier, Monique R, Hruz, Paul W, Ilagan, Ma Xenia G, Kraft, Thomas E, Odom, Audrey R, Payne, Maria A, Putanko, Marina, Thomas, David D   +9 more
core   +2 more sources