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Strategy for determination of LOD and LOQ values – Some basic aspects
Talanta, 2014The paper is devoted to the evaluation of limit of detection (LOD) and limit of quantification (LOQ) values in concentration domain by using 4 different approaches; namely 3σ and 10σ approaches, ULA2 approach, PBA approach and MDL approach. Brief theoretical analyses of all above mentioned approaches are given together with directions for their ...
exaly +3 more sources
Experimental Comparison of the Different Approaches To Estimate LOD and LOQ of an HPLC Method
Analytical Chemistry, 1999Detection and quantification limits (LOD and LOQ) are two fundamental elements of method validation. Rigorous statistical definitions exist, but in HPLC they could not be implemented. Nevertheless there are several estimation methods for these limits. The most commonly used is the signal-to-noise ratio criterion.
Jérôme Vial, Alain Jardy
exaly +2 more sources
Journal of Breath Research, 2016
Biomarker datasets often include entries 'below the level of quantitation' (LoQ) wherein the instrumentation is no longer able to provide values that meet required analytical quality standards, a phenomenon referred to as 'left-censored' data. Generally, some form of imputation for missing values is required to allow calculating distributions and ...
Joachim D Pleil
exaly +3 more sources
Biomarker datasets often include entries 'below the level of quantitation' (LoQ) wherein the instrumentation is no longer able to provide values that meet required analytical quality standards, a phenomenon referred to as 'left-censored' data. Generally, some form of imputation for missing values is required to allow calculating distributions and ...
Joachim D Pleil
exaly +3 more sources
2021
Optical methods (light or electron microscopy) are, in most cases, the basis for measuring the asbestos concentration either in air or in materials. The individual methods are described in a variety of guidelines or standards. The definition of terms like detection limit and analytical sensitivity have led to numerous discussions, driven by the fact ...
exaly +2 more sources
Optical methods (light or electron microscopy) are, in most cases, the basis for measuring the asbestos concentration either in air or in materials. The individual methods are described in a variety of guidelines or standards. The definition of terms like detection limit and analytical sensitivity have led to numerous discussions, driven by the fact ...
exaly +2 more sources
European Food Research and Technology, 2008
The predominant approach for quantification of genetically modified organisms (GMO) is the application of quantitative real-time PCR. However, for a large number of processed food and feed products, this approach is unsuitable, because they contain low amounts (mass) of amplifiable DNA. Here we present a novel approach, “Single molecule quantification”
Arne Holst-Jensen, Knut G Berdal
exaly +2 more sources
The predominant approach for quantification of genetically modified organisms (GMO) is the application of quantitative real-time PCR. However, for a large number of processed food and feed products, this approach is unsuitable, because they contain low amounts (mass) of amplifiable DNA. Here we present a novel approach, “Single molecule quantification”
Arne Holst-Jensen, Knut G Berdal
exaly +2 more sources
Carbohydrate Polymers, 2021
Hybrid nanocomposite thin film for hydrogen sulfide (H2S) gas sensor based on bacterial cellulose nanocrystals (BCNCs) has resulted in high demand of environmentally friendly nanomaterials. Films were prepared using thermal spray coating that sprayed hybrid nanocomposite suspension based on silver nanoparticles (AgNPs)-loaded BCNCs's surface and ...
Pongpat, Sukhavattanakul +1 more
openaire +2 more sources
Hybrid nanocomposite thin film for hydrogen sulfide (H2S) gas sensor based on bacterial cellulose nanocrystals (BCNCs) has resulted in high demand of environmentally friendly nanomaterials. Films were prepared using thermal spray coating that sprayed hybrid nanocomposite suspension based on silver nanoparticles (AgNPs)-loaded BCNCs's surface and ...
Pongpat, Sukhavattanakul +1 more
openaire +2 more sources
Insect Biochemistry and Molecular Biology, 2015
The phenomenon of RNA interference (RNAi) has been found in various organisms. However, the proteins implicated in RNAi pathway in different species show distinct roles. Knowledge on the underlying mechanism of lepidopteron RNAi is quite lacking such as the roles of Loquacious (Loqs) and R2D2, the dsRNA-binding proteins in silkworm RNAi pathway.
Li, Zhu +6 more
openaire +2 more sources
The phenomenon of RNA interference (RNAi) has been found in various organisms. However, the proteins implicated in RNAi pathway in different species show distinct roles. Knowledge on the underlying mechanism of lepidopteron RNAi is quite lacking such as the roles of Loquacious (Loqs) and R2D2, the dsRNA-binding proteins in silkworm RNAi pathway.
Li, Zhu +6 more
openaire +2 more sources