Results 51 to 60 of about 1,751 (155)

Central neuropathic pain in paraplegia alters movement related potentials [PDF]

, 2018
Objectives: Spinal Cord Injured (SCI) persons with and without Central Neuropathic Pain (CNP) show different oscillatory brain activities during imagination of movement.
Fraser, Matthew, Hasan, Muhammad Abul, Jarjees, Mohammed, Miyakoshi, Makoto, Vuckovic, Aleksandra   +4 more
core   +1 more source

Implication of the thalamus in sleep alterations observed in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep‐dependent memory ...
Carla Burnet‐Merlin, Y. Audrey Hay, Aurélie Brécier   +2 more
wiley   +1 more source

Pathophysiological Models of Hypersomnolence Associated With Depression

Biological Psychiatry Global Open Science
Up to 25% of patients with depression experience hypersomnolence (e.g., excessive daytime sleepiness, hypersomnia, and/or sleep inertia), which is associated with treatment resistance, overall poorer outcomes, and safety concerns while driving ...
Christophe Moderie, Diane B. Boivin
doaj   +1 more source

Increasing Evidence for the Use of Sodium Oxybate in Multi-Drug- Resistant Lance–Adams Syndrome [PDF]

, 2019
Background: Treatment of posthypoxic myoclonus (PHM) can be a challenge in patients not responsive to first-line medications. PMH is a rare condition that has a dramatic impact on patients’ quality of life. Refractory cases are not uncommon. Case Report:
Frucht, Steven J., Riboldi, Giulietta M.
core   +2 more sources

Emergency department presentations, hospitalisations and police seizure data related to gamma‐hydroxybutyrate (GHB) in New South Wales, Australia, from 2015 to 2024

Addiction, Volume 121, Issue 2, Page 305-315, February 2026.
Abstract Background and aims Gamma‐hydroxybutyrate (GHB) is an endogenous neurochemical and illicit synthetic drug. Its precursors, gamma‐butyrolactone (GBL) and 1,4‐butanediol (1,4‐BD), are often used as substitutes. We aimed to describe GHB‐related harms in New South Wales (NSW), Australia.
Krista J. Siefried, Janette L. Smith, Christine A. Harvey, Anthony Nedanoski, Jared A. Brown, Una Cullinan, Nadine Ezard, Thanjira Jiranantakan, Darren M. Roberts, Jonathan Brett   +9 more
wiley   +1 more source

Expanding the Genetic and Phenotypic Spectrum of DYT‐VPS16: The Importance of Splice‐Site Variants

Movement Disorders, Volume 41, Issue 1, Page 84-94, January 2026.
Abstract Background DYT‐VPS16, an early‐onset isolated dystonia caused by variants in the VPS16 gene, has been reported in fewer than 70 patients. Methods We explored the clinical and genotypic spectrum of DYT‐VPS16 by investigating early‐onset dystonia patients with VPS16 variants discovered in our large Biodatabank and through gene‐matching ...
Ana Westenberger, Edgard Verdura, Mandy Radefeldt, Leslie E. Sanderson, Kornelia Tripolszki, Anna Marcé‐Grau, Ana Cazurro‐Gutiérrez, Anita Nikoncuk, Rebecca Herzog, Ruslan Al‐Ali, Mariana Ferreira, Ligia S. Almeida, Tainá Regina Damaceno Silveira, Suliman Khan, Raphael Doyle Maia, Péter Klivényi, András Salamon, Volkan Baltaci, Asli Subasioglu, Jeanette Prada‐Arismendy, Goran Čuturilo, Sebastian Loens, Vera Tadic, Isabelle Maystadt, Deniz Karadurmus, Barbara Leube, Jonathan De Winter, Alice Monticelli, Liesbeth De Waele, Jonathan Baets, Mateja Vinkšel, Aleš Maver, Lorena Tschopp, Gabriela Ziegler, Ana Sanguinetti, Katja Lohmann, Tahsin Stefan Barakat, Peter Bauer, Belén Perez‐Dueñas, Aida M. Bertoli‐Avella   +39 more
wiley   +1 more source

Source inference of exogenous gamma-hydroxybutyric acid (GHB) administered to humans by means of carbon isotopic ratio analysis: novel perspectives regarding forensic investigation and intelligence issues [PDF]

, 2018
γ-Hydroxybutyric acid (GHB) is an endogenous short-chain fatty acid popular as a recreational drug due to sedative and euphoric effects, but also often implicated in drug-facilitated sexual assaults owing to disinhibition and amnesic properties.
Marclay, François, Saudan, Christophe, Saugy, Martial, Tafti, Mehdi, Vienne, Julie   +4 more
core  

A Review of the Risk Factors, Pathophysiology, Diagnosis and Treatment of Narcolepsy [PDF]

, 2022
Narcolepsy is hypothesized to be an autoimmune disease targeting the hypocretin/orexin producing neurons within the hypothalamus and is categorised into subsets based on the symptoms presented.
Jervis, Steven, Lowe, Marcus, Payton, Antony, Poulton, Kay, Thomasson, Rachel, Verma, Arpana   +5 more
core  

Prolonged Detection of GHB Intake in Urine: Are We Finally There?

Drug Testing and Analysis, Volume 17, Issue 12, Page 2429-2446, December 2025.
In a randomised placebo‐controlled trial with 30 volunteers, urinary LC‐MS/MS analysis demonstrated that a tentative GHB‐pentose conjugate remained elevated in urine up to 72 h post‐administration. This biomarker showed clear distinction from placebo and may offer extended detection compared to GHB itself, representing a significant step forward in ...
Kathrine B. Faldborg, Jørgen B. Hasselstrøm, Thomas Kraemer, Charlotte U. Andersen, Andrea E. Steuer   +4 more
wiley   +1 more source

Treatment of Neurogenic Voice Disorders

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 11, Issue 4, Page 541-547, December 2025.
ABSTRACT This overview serves as a foundational resource for clinicians caring for neurologically complex patients presenting with voice complaints. Neurogenic voice disorders are diverse in their clinical presentations and therapeutic approaches. A thorough medical history, including family history, detailed laryngeal examination, voice assessments ...
Mausumi Syamal
wiley   +1 more source