Results 31 to 40 of about 1,788 (174)

European guideline and expert statements on the management of narcolepsy in adults and children [PDF]

, 2021
Background and purpose: Narcolepsy is an uncommon hypothalamic disorder of presumed autoimmune origin that usually requires lifelong treatment. This paper aims to provide evidence-based guidelines for the management of narcolepsy in both adults and ...
Baldin, Elisa, Bassetti, Claudio L. A., Dauvilliers, Yves, Dolenc-Groselj, Leja, Jennum, Poul, Kallweit, Ulf, Khatami, Ramin, Lammers, Gert J., Lecendreux, Michel, Manconi, Mauro, Mayer, Geert, Partinen, Markku, Plazzi, Giuseppe, Pollmaecher, Thomas, Reading, Paul, Santamaria, Joan, Sonka, Karel, Vignatelli, Luca   +17 more
core   +11 more sources

Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4 butanediol (1,4-BD; BDO) : a literature review with a focus on UK fatalities related to non-medical use [PDF]

, 2015
Misuse of gamma hydroxybutrate (GHB) and gamma butyrolactone (GBL) has increased greatly since the early 1990s, being implicated in a rising number of deaths.
Abanades, Abanades, Absalom, ACMD, Adinoff, Akins, Al-Samarrie, Altose, Andresen, Andresen, Andresen-Streichert, Andresen-Streichert, Arena, Aromatario, Atha, Atha, Barbara Loi, Barker, Baselt, Beghè, Bennett, Bessman, Black, Blanchflower, Bluelight, Bluet-Pajot, BNF, Borgen, Borgen, Bosch, Bosman, Bourne, Boyd, Brailsford, Brenneisen, Brunt, Burch, Busardò, Cagnin, Caldicott, Caputo, Caputo, Carai, Carter, Catalano, Cheston, Chien, Chin, Christine Goodair, Coleman, Collier, Colombo, Colombo, Cook, Corkery, Corkery, Corkery, Couper, Couper, Couper, Couper, Couper, Crookes, Daily Mail, Dargan, Dargan, Davies, Davis, de Fiebre, DEA, DEA, DEA, Dhani, Dick, Dietze, Divry, DPA, Drugs-Forum, Dudek, Duer, Dunn, Dupont, Durgahee, Dyer, Dyer, Elian, Elliott, Elliott, Elliott, Elliott, Elliott, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMCDDA, EMEA, EMEA, Erowid, Erowid, Erowid, Erowid, Evans, Fabrizio Schifano, Fadda, Feigenbaum, Ferrara, Ferrara, Ferrara, Fieler, FIRE, Franchitto, Frase, Friedman, Gahr, Galicia, Gallimberti, Gallimberti, Gallimberti, Galloway, Galloway, Galloway, Gerot Lannach Pharma GmbH., Gerra, Gheshlaghi, Gianutsos, Goodwin, Guidotti, Hagemann, Hansard, Harty, Hechler, Helrich, Herbert, Heytens, Hibell, Hibell, Hibell, Hodges, Hoes, Home Office, Home Office, Hopkins, Horyniak, Hugh Claridge, Hunter, Itzhak, John M. Corkery, Jones, Jones, Kalasinsky, Kam, Kamal, Kapil, Karch, Kaufman, Keating, Kelly, Kilgore, Kim, Kintz, Kintz, Knudsen, Korb, Korf, Kraner, Krul, Kugelberg, Laboratorio Farmaceutico C.T. Srl., Laborit, Laborit, Laborit, Lamb, Langford, LeBeau, Lenz, LeTourneau, Lettieri, Liechti, Liechti, Louagie, Luby, Lycaeum, Maitre, Maitre, Mamelak, Mamelak, Maremmani, Mari, Marinetti, Marinetti, Marston, Mason, Mazarr-Proo, McCabe, McCambridge, McCusker, McDaniel, McDonough, McDowell, Measham, Measham, Meyer, Meyer, Mikelsson, Mindandmuscle, Miotto, Miró, Mixmag, Mixmag, Mixmag, Morbidity and Mortality Weekly Report, Moriya, Moriya, Morse, Mozayani, Munir, Murali, Mégarbane, Nava, Navarro, Neels, Nelson, Nutt, Németh, ONDCP, ONS, ONS, ONS, Ornella Corazza, Ortega-Albás, Our Insight, O’Connell, Palamar, Palatini, Pan, Pazos, Penberthy, Poldrugo, Poldrugo, Poldrugo, Pounder, Quang, Quang, Rahbeeni, ReDNet., Reisch, Roberts, Romanelli, Rossetti, Roth, Roth, Roth, Roth, Roth, Rønning, Sakurada, Samokhvalov, Sanguineti, Schifano, Schmitt, Schneidereit, Sevak, Sewell, Shannon, Shima, Shröck, Simon Elliott, Simonsen, Sindicich, Sivilotti, Skala, Smith, Snead, Snead, Snead, Snead, Snead, Sporer, Stephens, Stephens, Strickland, Sturman, Sumnall, Takahara, Teter, Thai, Thai, Theron, Thomas, U.S. Xyrem® Multicenter Study Group, Uys, van Amsterdam, van Amsterdam, van Noorden, van Rij, Van Sassenbroeck, Van Sassenbroeck, van Vugt, Vayer, Vayer, Vickers, Vree, Wang, Wang, Wang, Ward, Weißhaar, Wellendorph, WHO, Williams, Winstock, Winstock, Winstock, Winstock, Wojtowicz, Wood, Wood, Wood, Yeatman, Zapata, Zvosec, Zvosec, Zvosec   +324 more
core   +1 more source

Why dried blood spots are an ideal tool for CYP1A2 phenotyping [PDF]

, 2014
Background and Objective: Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies.
De Kesel, Pieter, Lambert, Willy, Stove, Christophe   +2 more
core   +2 more sources

Pain-related diseases and sleep disorders [PDF]

, 2012
Pain and sleep share mutual relations under the influence of cognitive and neuroendocrine changes. Sleep is an important homeostatic feature and, when impaired, contributes to the development or worsening of pain-related diseases.
Roizenblatt, Marina, Roizenblatt, Suely, Rosa Neto, Nilton Salles, Tufik, Sergio   +3 more
core   +4 more sources

Changes in Cataplexy Frequency in a Clinical Trial of Lower-Sodium Oxybate with Taper and Discontinuation of Other Anticataplectic Medications [PDF]

, 2022
Correction:Background Lower-sodium oxybate (LXB) is an oxybate medication with the same active moiety as sodium oxybate (SXB) and a unique composition of cations, resulting in 92% less sodium.
Black, Jed, Bogan, Richard K., Chen, Abby, Dauvilliers, Yves, Del Rio Villegas, Rafael, Foldvary-Schaefer, Nancy, Partinen, Markku, Skobieranda, Franck, Skowronski, Roman, Sonka, Karel, Thorpy, Michael J.   +10 more
core   +2 more sources

Narcolepsy 2025 (with an Australasian perspective). [PDF]

Intern Med J
Abstract Narcolepsy is a disorder of central hypersomnolence, which, while uncommon, can carry profound implications for affected individuals. Despite this, it remains under‐recognised within the medical community and presents frequent diagnostic and treatment challenges in the Australasian setting.
Lin A, Yee BJ, Tai JE, Sivam S.
europepmc   +2 more sources

Central neuropathic pain in paraplegia alters movement related potentials [PDF]

, 2018
Objectives: Spinal Cord Injured (SCI) persons with and without Central Neuropathic Pain (CNP) show different oscillatory brain activities during imagination of movement.
Fraser, Matthew, Hasan, Muhammad Abul, Jarjees, Mohammed, Miyakoshi, Makoto, Vuckovic, Aleksandra   +4 more
core   +1 more source

Nocturnal sodium oxybate increases the anterior cingulate cortex magnetic resonance glutamate signal upon awakening [PDF]

, 2023
Clinical guidelines recommend sodium oxybate (SXB; the sodium salt of γ-hydroxybutyrate) for the treatment of disturbed sleep and excessive daytime sleepiness in narcolepsy, yet the underlying mode of action is elusive.
Baur, Diego Manuel, Bosch, Oliver Gero, Dornbierer, Dario A, Hock, Andreas, Kraemer, Thomas, Landolt, Hans‐Peter, Quednow, Boris B, Seifritz, Erich, Stucky, Benjamin, Zölch, Niklaus   +9 more
core   +1 more source

Misdiagnosis of narcolepsy [PDF]

, 2016
BACKGROUND: Narcolepsy is a chronic primary sleep disorder, characterized by excessive daytime sleepiness and sleep dysfunction with or without cataplexy.
American Academy of Sleep Medicine, American Academy of Sleep Medicine, BB Wilford, D Arand, EJ Mignot, Emily L Maschauer, I Morrison, I Morrison, Ian Morrison, Laura Dunne, LE Krahn, LM Trotti, MH Silber, MR Littner, MW Johns, Pallavi Patel, Renata L Riha, RM Benca, S Dzodzomenyo, WA Broughton   +19 more
core   +3 more sources

Patients' perspective of the effectiveness and acceptability of pharmacological and non-pharmacological treatments of fibromyalgia. [PDF]

, 2018
Background and aims Fibromyalgia is a complex condition characterised by widespread pain, sleep disturbance, fatigue and cognitive impairment, with a global mean prevalence estimated at 2.7%.
Ashe, Simon, Furness, Penny, Haywood-Small, Sarah, Lawson, Kim, Steer, Michael, Taylor, Sophie   +5 more
core   +1 more source