Results 31 to 40 of about 8,676,773 (167)

Diagnostic Value of Psychomotor Vigilance Task for Severe Sleep Inertia in Idiopathic Hypersomnia Versus Other Sleep Disorders Without Sleep Inertia

Journal of Sleep Research, EarlyView.
Diagnostic Value of PVT for Severe Sleep Inertia in Idiopathic Hypersomnia. ABSTRACT Sleep inertia impairs performance upon awakening and may be assessed using the psychomotor vigilance task (PVT). This study aimed to determine optimal PVT lapse cut‐offs at awakening to objectively measure sleep inertia by comparing patients with idiopathic hypersomnia
Elisa Evangelista, Alexandre Derré, Lucie Barateau, Anna Laura Rassu, Sofiene Chenini, Isabelle Jaussent, Yves Dauvilliers   +6 more
wiley   +1 more source

Dosing and transition characteristics in people with narcolepsy transitioning from sodium oxybate to low-sodium oxybate: Data from the real-world TENOR study

Sleep Medicine
The Transition Experience of persons with Narcolepsy taking Oxybate in the Real-world (TENOR) study assessed the real-world experience of people with narcolepsy switching from sodium oxybate (SXB) to low-sodium oxybate (LXB; 92 % less sodium than SXB).TENOR is a patient-centric, prospective, observational, virtual-format study.
Aatif M, Husain, Phyllis C, Zee, Eileen B, Leary, Douglas S, Fuller, Wayne, Macfadden, Shawn, Candler, Marisa, Whalen, Charles J, Bae   +7 more
openaire   +2 more sources

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source

Sodium oxybate for excessive daytime sleepiness and sleep disturbance in Parkinson disease: A randomized clinical trial [PDF]

, 2018
IMPORTANCE: Sleep-wake disorders are a common and debilitating nonmotor manifestation of Parkinson disease (PD), but treatment options are scarce. OBJECTIVE: To determine whether nocturnal administration of sodium oxybate, a first-line treatment ...
Büchele, F, Maric, A, Omlor, W, Hackius, M, Hägele-Link, S, Baumann, CR, Imbach, LL, Waldvogel, D, Schreglmann, SR, Werth, E   +9 more
core   +2 more sources

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan, Suzan Linssen, Rolf Fronczek, Lucie Barateau, Christelle Peyron, Yves Dauvilliers   +5 more
wiley   +1 more source

Treatment of paediatric narcolepsy with sodium oxybate: a double-blind, placebo-controlled, randomised-withdrawal multicentre study and open-label investigation

, 2018
Background: Narcolepsy is a lifelong neurological disorder with onset commonly in childhood or adolescence. No drugs are indicated for cataplexy and excessive daytime sleepiness in paediatric patients with narcolepsy.
Ruoff, Chad, Dauvilliers, Yves, Wang, Youyu Grace, Michel Lecendreux, Rosen, Carol, Carol L Rosen, Parvataneni, Rupa, Chad Ruoff, Plazzi, Giuseppe, Guinta, Diane, Giuseppe Plazzi, Diane Guinta, Black, Jed, Rosen, Carol L, Youyu Grace Wang, Rupa Parvataneni, Jed Black, Yves Dauvilliers, Lecendreux, Michel, Mignot, Emmanuel, Emmanuel Mignot   +20 more
core   +1 more source

The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy [PDF]

, 2015
Contains fulltext : 154173.pdf (Publisher’s version ) (Closed access)Patients suffering from narcolepsy type 1 show altered skin temperatures, resembling the profile that is related to sleep onset in healthy controls.
Donjacour, CEHM Claire, Pijl, H., Heide, A., Donjacour, C.E., Fronczek, R Rolf, Reijntjes, Robert H A M, Overeem, S Sebastiaan, Lammers, Gert Jan Gert, van der Heide, A., Someren, EJW van, Reijntjes, R.H., Fronczek, R., Someren, van, E.J.W., van Someren, E.J.W., Lammers, G.J., Overeem, S.; id_orcid, Someren, E.J.W. van, Pijl, Hanno, Donjacour, C.E.H.M., van der Heide, A Astrid, Heide, A. van der, Overeem, S., Reijntjes, R.H.A.M.   +22 more
core   +1 more source

Is Sodium Oxybate a Safe and Effective Treatment for Patients with Fibromyalgia [PDF]

, 2012
Objective: The objective of this systematic review is to determine whether or not Sodium Oxybate is a safe and effective treatment of pain and sleep-related symptoms of fibromyalgia.
Grandinette, Britanie A
core   +1 more source

Risk of Hypertension and Mortality Among People With Narcolepsy or Idiopathic Hypersomnia: A Retrospective Cohort Analysis of the Danish National Patient Registry

Journal of Sleep Research, EarlyView.
This retrospective cohort study using data from the Danish National Patient Registry shows that individuals with narcolepsy or idiopathic hypersomnia have greater prevalence and risk of incident hypertension compared with matched controls, highlighting the elevated cardiovascular risk associated with these conditions.
Poul Jørgen Jennum, Michael Ibsen, Sam Mettam, Sarah C. Markt, Douglas S. Fuller, Jessica K. Alexander, Rikke Ibsen, Jakob Kjellberg, Caroleen Drachenberg   +8 more
wiley   +1 more source

Network Analysis in Central Disorders of Hypersomnolence: Insight Into Relationships Between Symptoms, Mental Health, and Quality of Life

Journal of Sleep Research, EarlyView.
Network Analysis in Central Disorders of Hypersomnolence: Insight Into Relationships Between Symptoms, Mental Health, and Quality of Life. ABSTRACT In the central disorders of hypersomnolence (CDH) narcolepsy types 1 and 2 (NT1, NT2) and idiopathic hypersomnia (IH), mental health problems are highly prevalent, and quality of life is decreased.
Denise Bijlenga, Tessa F. Blanken, Josephine J. de Boer, Rolf Fronczek, Gert Jan Lammers   +4 more
wiley   +1 more source