Results 101 to 110 of about 113,253 (324)

A retrospective record-based study to evaluate the profile of TB patients diagnosed and registered at DOTS center at the tertiary care center and to study the gaps in the implementation of the latest guidelines toward TB elimination

The Journal of Association of Chest Physicians
Context: Tuberculosis (TB) has infected mankind since time immemorial. India has been a breeding ground for this disease due to high population density and lack of awareness and education in the population.
Ruchi Arora Sachdeva, Sahil Singh, MK Sen   +2 more
doaj   +1 more source

LPA receptor signaling: pharmacology, physiology, and pathophysiology

Journal of Lipid Research, 2014
Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and nonvertebrate organisms that mediates diverse biological actions and demonstrates medicinal relevance. LPA’s functional roles are driven by extracellular signaling through at
Y. Yung, Nicole C. Stoddard, J. Chun
semanticscholar   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway

Frontiers in Physiology, 2018
Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role ...
Jinjing Yang, Jinjing Yang, Jinjing Yang, Jiyao Xu, Jiyao Xu, Xuebin Han, Xuebin Han, Hao Wang, Yuean Zhang, Yuean Zhang, Jin Dong, Jin Dong, Yongzhi Deng, Yongzhi Deng, Jingping Wang, Jingping Wang   +15 more
doaj   +1 more source

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species [PDF]

FEBS Letters, 2000
We examined the structure–activity relationship of cloned lysophosphatidic acid (LPA) receptors (endothelial cell differentiation gene (EDG) 2, EDG4, and EDG7) by measuring [Ca2+]i in Sf9 insect cells expressing each receptor using LPA with various acyl chains bound at either the sn‐1 or the sn‐2 position of the glycerol backbone.
Bandoh, Koji, Aoki, Junken, Taira, Akitsu, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo   +5 more
openaire   +2 more sources

European Identity in Youth: Longitudinal Dynamics and the Role of School Experiences

Journal of Adolescence, EarlyView.
ABSTRACT Introduction For young people in Europe, European identity can serve as an important source of solidarity and belonging, especially in times of growing societal polarization. This study investigates European identity development during adolescence with two aims: (1) to identify European identity profiles, their associations with civic and ...
Astrid Körner, Katharina Eckstein, Anna‐Maria Mayer, Philipp Jugert, Peter Noack   +4 more
wiley   +1 more source

Profiles of Psychological Capital and Work‐Related Well‐Being Among School Counselors During a Prolonged Emergency

Journal of Counseling &Development, EarlyView.
ABSTRACT School counselors face an elevated risk of burnout due to heavy workloads and sustained stress, particularly during prolonged emergencies. This study examined psychological capital, a positive psychology construct comprising hope, efficacy, resilience, and optimism, as a potential resource for promoting counselors’ work‐related well‐being ...
Yuliya Lipshits‐Braziler, Moshe Tatar, Ina Ben‐Uri, Sima Amram‐Vaknin   +3 more
wiley   +1 more source

Lipoprotein(a) accelerated the progression of atherosclerosis in patients with end-stage renal disease

BMC Nephrology, 2018
Background Increased plasma level of lipoprotein(a) (Lpa) is a risk factor of cardiovascular diseases. This study aimed to explore the role of Lpa in the progression of atherosclerosis in patients with end-stage renal disease (ESRD) and to investigate ...
Kun Ling Ma, Tie Kai Gong, Ze Bo Hu, Yang Zhang, Gui Hua Wang, Liang Liu, Pei Pei Chen, Jian Lu, Chen Chen Lu, Bi Cheng Liu   +9 more
doaj   +1 more source

Functional RG approach to the Potts model

, 2018
The critical behavior of the $(n+1)$-states Potts model in $d$-dimensions is studied with functional renormalization group techniques. We devise a general method to derive $\beta$-functions for continuos values of $d$ and $n$ and we write the flow ...
Codello, Alessandro, Zinati, Riccardo Ben Ali   +1 more
core   +1 more source

LPA receptor 1 mediates LPA-induced ovarian cancer metastasis: an in vitro and in vivo study

BMC Cancer, 2016
BackgroundThe facts that LPA is present at high concentration in ovarian cancer patients’ ascites and it may serve as a stimulator to cell migration, implicate the role of LPA in the ovarian cancer metastasis.
Xuechen B. Yu, Yuan-zhen Zhang, Huijun Chen   +2 more
semanticscholar   +1 more source