Changes in and the mediating role of physical activity in relation to active school transport, fitness and adiposity among Spanish youth: the UP&DOWN longitudinal study [PDF]
, 2020 Background Longitudinal changes in child and adolescent active school transport (AST), and the mediating role of different intensities of daily physical activity (PA) levels in relation to AST and physical fitness and adiposity indicators is unclear ...
Abbott, Gavin +9 more
core +3 more sources
Knockout of MULTI-DRUG RESISTANT PROTEIN 5 Genes Lead to Low Phytic Acid Contents in Oilseed Rape
Frontiers in Plant Science, 2020 Understanding phosphate uptake and storage is interesting to optimize the plant performance to phosphorus fluctuations. Phytic acid (PA) is the major source of inorganic phosphorus (Pi) in plants. Genetic analyses of PA pathway transporter genes (BnMRP5)
Niharika Sashidhar +2 more
doaj +1 more source
Brain Sciences, 2022 Preclinical evidence suggests a main role of lysophosphatidic acid (LPA) signaling in drug addiction. Recently, we reported alterations in the plasma concentrations of LPA species in patients with alcohol use disorder (AUD).
María Flores-López +13 more
doaj +1 more source
Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients [PDF]
PeerJ, 2020 Head and neck squamous cell carcinoma (HNSCC) represents a significant world health problem, with approximately 600,000 new cases being diagnosed annually. The prognosis for patients with HNSCC is poor and, therefore, the identification of biomarkers for
Mariati Abdul Rahman +10 more
doaj +2 more sources
A single amino acid determines preference between phospholipids and reveals length restriction for activation ofthe S1P4 receptor [PDF]
, 2004 Background<br/><br/> Sphingosine-1-phosphate and lysophosphatidic acid (LPA) are ligands for two related families of G protein-coupled receptors, the S1P and LPA receptors, respectively.
Fells, J.I. +6 more
core +3 more sources
Cross-sectional associations between sleep duration, sedentary time, physical activity, and adiposity indicators among Canadian preschool-aged children using compositional analyses [PDF]
, 2017 Background Sleep duration, sedentary behaviour, and physical activity are three co-dependent behaviours that fall on the movement/non-movement intensity continuum.
AG LeBlanc +42 more
core +4 more sources
Non-Edg family LPA receptors: the cutting edge of LPA research [PDF]
Journal of Biochemistry, 2011 Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and pathological actions on many types of cells. Originally, LPA was thought to elicit its biological functions through three subtypes of endothelial differentiation gene (Edg) family G protein-coupled receptors (LPA1, LPA2 and LPA3) until our group identified a fourth
Keisuke, Yanagida, Satoshi, Ishii
openaire +2 more sources
Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers. [PDF]
PLoS ONE, 2014 Lysophosphatidic acid (LPA) is a natural bioactive lipid with growth factor-like functions due to activation of a series of six G protein-coupled receptors (LPA₁₋₆).
Marion David +7 more
doaj +1 more source
Cells, 2022 Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is continuously monitored by microglia. In the CNS, these changes include increased synthesis of the bioactive lipid lysophosphatidic acid (LPA), a ligand for the
Lisha Joshi +10 more
doaj +1 more source
European Journal of Psychotraumatology, 2018 Background: The proposed ICD-11 criteria for trauma-related disorders define posttraumatic stress disorder (PTSD) and complex posttraumatic stress disorder (cPTSD) as separate disorders.
Maria Böttche +7 more
doaj +1 more source